Shigeru Sato, PhD
Senior Assistant Professor
Division of Biology
Center for Molecular Medicine
Jichi Medical University
Yakuishiji, Minamikawachi, Tochigi 329-0498
JAPAN
Research
1) Development of cranial placodes and sensory organs
2) Evolution of cranial placodes and sensory organs
Education/Postdoctral training
BSc, Tohoku University Faculty of Science, 1989
MSc, Tohoku University, Graduate School of Science, 1991
PhD, Tohoku University, Graduate School of Science, 1995
Postdoc, Marie Curie Research Institute, UK, 1995
Postdoc, JSPS, Tohoku University, Graduate School of Science, 1996-1998
Publications
Original articles (times cited according to ISI Web of Knowledge)
1. Yamamoto, H., Kudo, T., Masuko, N., Miura, H., Sato, S., Tanaka, M., Tanaka, S., Takeuchi, S., Shibahara, S. and Takeuchi, T. (1992). Phylogeny of regulatory regions of vertebrate tyrosinase genes. Pigment Cell Res 5, 284−294. (25)
2. Sato, S., Miura, H., Yamamoto, H. and Takeuchi, T. (1994). Identification of nuclear factors that bind to the mouse tyrosinase gene regulatory region. Pigment Cell Res 7, 279−284. (2)
3. Sato, S., Masuya, H., Numakunai, T., Satoh, N., Ikeo, K., Gojobori, T., Tamura, K., Ide, H., Takeuchi, T. and Yamamoto, H. (1997). Ascidian tyrosinase gene: its unique structure and expression in the developing brain. Dev Dyn 208, 363−374. (35)
4. Sato, S.*, Roberts, K.*, Gambino, G., Cook, A., Kouzarides, T. and Goding, C.R. (1997). CBP/p300 as a co-factor for the Microphthalmia transcription factor. Oncogene 14, 3083−3092. (*equal contribution) (84)
5. Wada, H., Holland, P.W., Sato, S., Yamamoto, H. and Satoh, N. (1997). Neural tube is partially dorsalized by overexpression of HrPax-37: the ascidian homologue of Pax-3 and Pax-7. Dev Biol 187, 240−252. (83)
6. Yuasa, H.J., Sato, S., Yamamoto, H. and Takagi, T. (1997). Structure of the ascidian, Halocynthia roretzi, troponin C gene. J Biochem (Tokyo) 121, 671−676. (11)
7. Yuasa, H.J., Sato, S., Yamamoto, H. and Takagi, T. (1997). Primary structure of troponin I isoforms from the ascidian Halocynthia roretzi. J Biochem (Tokyo) 122, 374−380. (9)
8. Amae, S., Fuse, N., Yasumoto, K., Sato, S., Yajima, I., Yamamoto, H., Udono, T., Durlu, Y.K., Tamai, M., Takahashi, K. and Shibahara, S. (1998). Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium. Biochem Biophys Res Commun 247, 710−715. (70)
9. Ohto, H., Kamada, S., Tago, K., Tominaga, S.I., Ozaki, H., Sato, S. and Kawakami, K. (1999). Cooperation of Six and Eya in Activation of Their Target Genes through Nuclear Translocation of Eya. Mol Cell Biol 19, 6815−6824. (135)
10. Sato, S., Toyoda, R., Katsuyama, Y., Saiga, H., Numakunai, T., Ikeo, K., Gojobori, T., Yajima, I. and Yamamoto, H. (1999). Structure and developmental expression of the ascidian TRP gene: insights into the evolution of pigment cell-specific gene expression. Dev Dyn 215, 225−237. (24)
11. Yajima, I.*, Sato, S.*, Kimura, T., Yasumoto, K., Shibahara, S., Goding, C.R. and Yamamoto, H. (1999). An L1 element intronic insertion in the black-eyed white (Mitfmi-bw) gene: the loss of a single Mitf isoform responsible for the pigmentary defect and inner ear deafness. Hum Mol Genet 8, 1431−1441. (*equal contribution) (59)
12. Toyoda, R., Sato, S., Ikeo, K., Gojobori, T., Numakunai, T., Goding, C.R. and Yamamoto, H. (2000). Pigment cell-specific expression of the tyrosinase gene in ascidians has a different regulatory mechanism from vertebrates. Gene 259, 159−170. (6)
13. Sato, S., Tanaka, M., Miura, H., Ikeo, K., Gojobori, T., Takeuchi, T. and Yamamoto, H. (2001). Functional conservation of the promoter regions of vertebrate tyrosinase genes. J Investig Dermatol Symp Proc 6, 10−18. (7)
14. Sato, S., Nakamura, M., Cho, D.H., Tapscott, S.J., Ozaki, H. and Kawakami, K. (2002). Identification of transcriptional targets for Six5: Implication for the pathogenesis of myotonic dystrophy type 1. Hum Mol Genet 11, 1045−1058. (16)
15. Kumasaka, M., Sato, S., Yajima, I. and Yamamoto, H. (2003). Isolation and developmental expression of tyrosinase family genes in Xenopus laevis. Pigment Cell Res 16, 455−462. (11)
16. Yajima, I., Endo, K., Sato, S., Toyoda, R., Wada, H., Shibahara, S., Numakunai, T., Ikeo, K., Gojobori, T., Goding, C.R. and Yamamoto, H. (2003). Cloning and functional analysis of ascidian Mitf in vivo: insights into the origin of vertebrate pigment cells. Mech Dev 120, 1489−1504. (1)
17. Kumasaka, M., Sato, H., Sato, S., Yajima, I. and Yamamoto, H. (2004). Isolation and developmental expression of Mitf in Xenopus laevis. Dev Dyn 230, 107−113, 2004. (5)
18. Toyoda, R., Kasai, A., Sato, S., Wada, S., Saiga, H., Ikeo, K., Gojobori, T., Numakunai, T. and Yamamoto, H. (2004). Pigment cell lineage-specific expression activity of the ascidian tyrosinase-related gene. Gene 332, 61−69. (2)
19. Ando, Z-I., Sato, S., Ikeda, K. and Kawakami, K. (2005). Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4. FEBS J 27, 3026−3041. (8)
20. Kumasaka, M., Sato, S., Yajima, I., Goding, C.R. and Yamamoto, H. (2005). Regulation of melanoblast and retinal pigment epithelium development by Xenopus laevis Mitf. Dev Dyn 234, 523−534. (7)
21. Ikeda, K., Ookawara, S., Sato, S., Ando, Z., Kageyama, R. and Kawakami, K. (2007). Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol 311, 53-68. (10)
22. Ishihara, T., Ikeda, K., Sato, S., Yajima, H. and Kawakami, K. (2008). Differential expression of Eya1 and Eya2 during chick early embryonic development. Gene Expr Patterns 8, 357-67. (5)
23. Ishihara, T., Sato, S., Ikeda, K., Yajima, H. and Kawakami, K. (2008). Multiple evolutionarily conserved enhancers control expression of Eya1. Dev Dyn 237, 3142-56. (0)
24. Sato, S.**, Ikeda, K., Shioi, G., Ochi, H, Ogino, H. Yajima, H. and Kawakami, K. Conserved expression of mouse Six1 in the pre-placodal region (PPR) and identification of an enhancer for the rostral PPR. Dev Biol 344, 158-171 (2010). (**corresponding author)
25. Yajima, H., Motohashi, N., Sato, S., Ikeda, K., Masuda, S., Yada, E., Suzuki, Y., Takeda, S. and Kawakami, K. Six family genes control the proliferation and differentiation of muscle satellite cells. submitted for publication.
Review articles (times cited according to ISI Web of Knowledge)
26. Kawakami, K., Sato, S., Ozaki, H. and Ikeda, K. (2000). Six family genes-structure and function as transcription factors and their roles in development. Bioessays 22, 616−626. (134)
27. Sato, S. and Yamamoto, H. (2001). Development of pigment cells in the brain of ascidian tadpole larvae: insights into the origins of vertebrate pigment cells. Pigment Cell Res 14, 428−436. (9)
Other articles (times cited according to ISI Web of Knowledge)
28. The International Myotonic Dystrophy Consortium (IDMC). (2000). New nomenclature and DNA testing guidelines for myotonic dystrophy type 1 (DM1). Neurology 54, 1218-1221. (73)
Books
29. Kawakami, K. and Sato, S. (2004) Roles of homeobox protein Six1 in the formation of sensory organs. Exp Med, 22, 1702-1708 (in Japanese).