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	2013 1. Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, NakayamaJ, Sagara J, Taniguchi S, Kimata K, Ikeda U. Critical role of hyaluronanin neointimal formation after vascular injury. PLoS One 8: e58760, 2013 2. Takahashi M. NLRP3 in myocardial ischemia-reperfusion injury: Inflammasome-dependent or -independent role in different cell types. Cardiovasc Res 99: 4-5, 2013 3. Inoue Y, Yasuda Y, Takahashi M. Role of the inflammasome in inflammatoryresponses and subsequent injury after hepatic ischemia-reperfusion injury. Hepatology 58: 2212, 2013 4. Koyama J, Minamisawa A, Aizawa K, Kasai H, Koshikawa M, Izawa A, TomitaT, Miyashita Y, Kumazaki S, Takahashi M, Ikeda U. Peak systolic velocityof pulmonary venous flow and peak systolic mitral annular velocity areindependent predictors of left ventricular global longitudinal strain inpatients with cardiomyopathy. Int J Cardiol 168: 5462-5464, 2013 5. Takahashi M. Role of innate immune system in inflammation and cardiacremodeling after myocardial infarction. Curr Vascular Pharm 2013 Apr 29. [Epub ahead of print] 2012 1. Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S, Takahashi M. Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in western diet-fed apolipoprotein E-deficient Mice. Biochem Biophys Res Commun 425:162-168, 2012 2. Usui F, Kimura H, Ohshiro T, Tatsumi K, Kawashima A, Nishiyama A, Iwakura Y, Ishibashi S, Takahashi M. Interleukin-17 deficiency reduced vascular inflammation and development of atherosclerosis in western diet-induced ApoE-deficient mice. Biochem Biophys Res Commun 420:72-77, 2012 3. Takahashi M. Adipose tissue : an alternative source for therapeutic angiogenesis. Circ J 76:1597-1598, 2012 4. Takahashi M. Role of the inflammasome in vascular injury and atherosclerosis. Inflammation and Regeneration 32:112-118, 2012 5. Matsui A, Yokoo H, Negishi Y, Endo-Takahashi Y, Chun N, Kadouchi I, Suzuki R, Maruyama K, Aramaki Y, Semba K, Kobayashi E, Takahashi M, Murakami T. CXCL17 expression by tumor cells recruits CD11b+Gr-1highF4/80– cells and promotes tumor progression. PLoS One 7: 44080, 2012 6. Iwama S, De Remigis A, Bishop JA, Kimura HJ, Caturegli P. hurthle cells predict hypothyroidism in interferon-γ transgenic mice of different genetic backgrounds. Endocrinology 153: 4059-66, 2012 7. Kobayashi M, Morita T, Chunn NAL, Matsui A, Takahashi M, Murakami T. Effect of host immunity on metastatic potential in renal cell carcinoma: the assessment of optimal in vivo models to study metastatic behabior of renal cells. Tumor Biol 33: 551-559, 2012 8. Takeda S, Chinda J, Murakami T, Numata A, Iwazu Y, Akimoto T, Hamano Y, Muto S, Takahashi M, Kusano E. Development of features of glomerulopathy in tumor-bearing rats: a potential model for paraneoplastic glomerulopathy. Nephrol Dial Transplant 27:1786-1792, 2012 9. Hosoya A, Hiraga T, Ninomiya T, Yukita S, Yoshiba K, Yoshiba N, Takahashi M, Ito S, Nakamura H. Thy-1 positive cells in the subodontoblastic layer posess high potential to differentiate into hard tissue-forming cells. Histochem Cell Biol 137:733-742, 2012 10. Hosoya A, Yukita A, Yoshiba K, Yoshiba N, Takahashi M, Nakamura H. Two distinct processes of bone-like tissue formation by dental pulp cells after tooth transplantation. J Histochem Cytochem 60:861-873,2012 11. Motoki H, Koyama J, Nakazawa H, Aizawa K, Kasai H, Izawa A, Tomita T, Miyashita Y, Kumazaki S, Takahashi M, Ikeda U. Torsion analysis in the early detection of anthracycline-mediated cardiomyopathy. Eur Heart J Cardiovasc Imaging 13: 95-103, 2012 12. Akita S, Kubota K, Kobayashi A, Misawa R, Shimizu A, Nakata T, Yokoyama T, Takahashi M, Miyagawa S. Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by choline-deficient/ethionone-supplemented diet. Biochem Biophys Res Commun 420:743-749, 2012 13. Kasai H, Kashima Y, Izawa A, Tomita T, Miyashita Y, Koyama J, Takahashi M, Yoshio T, Yazaki Y, Higuchi M, Ikeda U. Immunoadsorption therapy reduces oxidative stress in patients with dilated cardiomyopathy. World J Cardiovasc Dis 2: 305-312, 2012 14. Tezuka Y, Endo S, Matsui A, Sato A, Sito K, Semba K, Takahashi M, Murakami T. Potential anti-tumor effect of IFN-ramda2 (IL-28A) against human lung cancer cells. Lung Cancer 78: 185-192, 2012 2011 1. Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U. Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia reperfusion injury. Circulation 123: 594-604, 2011 (Circulation's Best Paper Award of Basic Science 2011) 2. Takahashi M. Role of the inflammasome in myocardial infarction. Trends Cardiovasc Med 21:37-41, 2011 3. Hata T, Takahashi M, Hida S, Kawaguchi M, Kashima Y, Usui F, Morimoto, Nishiyama A, Izawa A, Koyama J, Iwakura Y, Taki S, Ikeda U. Critical role of Th17 cells in inflammation and neovascularization after ischemia. Cardiovasc Res 90: 364-372, 2011 4. Motoki H, Koyama J, Tomita T, Aizawa K, Kasai H, Koshikawa M, Izawa A, Kumazaki S, Takahashi M, Ikeda U. Transient peudorestrictive pattern of transmitral flow velocity curve in patients with paroxysmal atrial fibrillation. Echocardiology 28: 289-297, 2011 5. Yamaguchi A, Murakami T，Takahashi M, Kobayashi E，Sugawara Y. Luminescence imaging of regenerating free bone graft in rats. Plast Reconstr Surg 127: 78-87, 2011 6. Takahashi S, Ito T, Zenimaru Y, Suzuki J, Miyamori I, Takahashi M, Takahashi M, Ishida T, Ishida T, Hirata K, Yamamoto T, Iwasaki T, Hattori H, Shiomi M. Species differences of macrophage very low-density lipoprotein (VLDL) receptor protein expression. Biochem Biophys Res Commun 407: 656-662, 2011 7. Kinugasa S, Tojo A, Sakai T, Tsumura H, Takahashi M, Hirata Y, Fujita T. Selective albuminuria via podocyte albumin transport in puromycin nephritic rats is attenuated by an inhibitor of NADPH oxidase. Kidney Int 80:1328-1338, 2011 8. Sekine H, Shimizu T, Dobashi I, Matsuura K, Hagiwara N, Takahashi M, Kobayashi E, Yamato M, Okano T. Cardiac cell sheet transplantation improves damaged heart function via superior cell survival in comparison with dissociated cell injection. Tissue Eng 17: 2973-2980, 2011 9. Ise M, Ise H, Shiba Y, Kobayashi S, Goto M, Takahashi M, Akaike T, Ikeda U. Targeting N-acetylglucosamine-bearing polymer-coated liposomes to vascular smooth muscle cells. J Artif Organ 14: 301-309, 2011 2010 1. Takahashi M. Role of the SDF-1/CXCR4 system in myocardial infarction. Circ J 74: 418-423, 2010 2. Abe H, Takahashi M, Yaegashi H, Eda S, Tsunemoto H, Kamikozawa M, Koyama J, Yamazaki K, Ikeda U. The efficacy of continuous positive airway pressure on arrhythmias in obstructive sleep apnea patients. Heart and Vessels 25: 63-69, 2010 3. Takahashi M. Immature erythroid cells: a new source for therapeutic angiogenesis? J Mol Cell Cardiol 49: 341-342, 2010 4. Ise H, Kobayashi S, Goto M, Sato T, Kawakubo M, Takahashi M, Ikeda U. Vimentin and desmin possess GlcNAc-binding lectin-like properties on cell surfaces. Glycobiology 20: 843-864, 2010 5. Kumazaki S, Koyama J, Aizawa K, Kasai H, Koshikawa M, Izawa A, Tomita T, Takahashi M, Ikeda U. Effect of graft adaptation of the internal mammary artery on longitudinal phasic blood flow velocity characteristics after surgery. Heart and Vessels 25: 515-521, 2010 6. Sun X, Wu Y, Gao W, Enjyoji K, Csizmadia E, Muller CE, Murakami T, Robson SC. Adenosine generation by CD39/ENTPD1 on CD4+Foxp3+ regulatory T cells dampens anti-tumor immunity. Gastroenterology 139: 1030-1040, 2010 7. Ohsawa I, Murakami T, Guo L, Enosawa S, Ishibashi N, Isaji S, Uemoto S, Kobayashi E. Chemopreventive anti-cancer agent acyclic retinoid suppresses allogeneic immune responses in rats. Int Immunophamacol 10: 985-989, 2010 8. Iwasaki J, Hata T, Hishikawa S, Fujimoto Y, Uemoto S, Murakami T, Kobayashi E. Use of rat segmental intestine for fetal pancreatic transplantation. Microsurgery 30: 296-301, 2010 9. Kobayashi M, Murakami T, Uchibori R, Chun NAL, Kobayashi E, Ozawa K, Morita T. Establishment and characterization of transplantable luminescence-labeled rat renal cell carcinoma cell lines. J Urol 183: 2029-2035, 2010 10. Murai K, Sakai D, Nakamura Y, Nakai T, Igarashi T, Seo N, Murakami T, Kobayashi E, Mochida J. Primary immune system responders to nucleus pulposus cells: evidence for immune response in disc herniation. Eur Cells Mater 19: 13-21, 2010 11. Kimura M, Murakami T, Kizaka-Kondoh S, Itoh M, Yamamoto K, Hojo Y, Takano M, Kario K, Shimada K, Kobayashi E. Functional molecular imaging of integrin-linked kinase-Akt/PKB-mediated signaling and associated role of beta-parvin. J Cell Sci 123: 747-755, 2010 12.Murakami T. Transcriptional modulation using histone deacetylase inhibitors for cancer immunotherapy (Chapter 14). In “Experimental and Applied Immunotherapy”. Edited by Medin J.A. & Fower D.H. 2010 Nov30, pp 307-322. Humana Press, Springer (New York). 2009 1. Takahashi M. Genetic susceptibility to restenosis: Role of bone marrow cells and inflammatory response (Editorial) Arterioscler Thromb Vasc Biol 10: 1407-1408, 2009 2. Takahashi M. Therapeutic angiogenesis and regeneration in cardiovascular diseases. (Guest Editor) Curr Pharm Design 15: 2759, 2009 3. Shiba Y, Takahashi M, Hata T, Murayama H, Morimoto H, Ise H, Nagasawa T, Ikeda U. Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis. Cardiovasc Res 81: 169-177, 2009 4. Suzuki J, Ueno M, Uno M, Hirose T, Zenimaru Y, Takahashi S, Osuga J, Ishibashi S, Takahashi M, Hirose M, Yamada M, Kraemer FB, Miyamori I. Effects of hormone-sensitive lipase-disruption on cardiac energy metabolism in response to fasting and refeeding. Am J Physiol Endocrinol Metb 297:E1115-1124,2009 5. Kobayashi S, Ise H, Takahashi M, Goto M, Akaike T, Ikeda U. Surface coating of bone marrow cells with N-acetylglucosamine for bone marrow implantation therapy. Biomaterials 30: 574-582, 2009 6. Abe H, Takahashi M, Yaegashi H, Eda S, Kitahara H, Tsunemoto H, Kamikozawa M, Koyama J, Yamazaki K, Ikeda U. Valve repair improves central sleep apnea in heart failure patients with valvular heart disease. Circ J 73: 2148-2153, 2009 7. Aso S, Yazaki Y, Kasai H, Takahashi M, Yoshio T, Yamamoto K, Ikeda U. Anti-beta1-adrenoreceptor autoantibodies and myocardial sympathetic nerve activity in chronic heart failure. Int J Cardiol 131: 240-245, 2009 8. Koshikawa M, Aizawa K, Kasai H, Izwa A, Tomita T, Kumazaki S, Tsutsui H, Koyama J, Shimodaira S, Takahashi M, Ikeda U. Elevated osteopontin levels in patients with peripheral arterial diseases. Angiology 60: 42-45, 2009 9. Misawa R, Soeda J, Ise H, Takahashi M, Kubota K, Mita A, Nakata T, Miyagawa S. Potential feasibility of early bone marrow cell injection into the spleen for creating functional hepatocytes. Transplantation 87: 1145-1154, 2009 10. Hiraga T, Ninomiya T, Hosoya A, Takahashi M, Nakamura H. Formation of bone-like mineralized matrix by periodontal ligament cells in vivo: a morphological study in rats. J Bone Miner Metab 27: 149-157, 2009 11. Doi H, Iso T, Shiba Y, Sato H, Yamazaki M, Oyama Y, Akiyama H, Tanaka T, Tomita T, Arai M, Takahashi M, Ikeda U, Kurabayashi M. Notch signaling regulates the differentiation of bone marrow-derived cells into smooth muscle-like cells during arterial lesion formation. Biochem Biophys Res Commun 381: 654-659, 2009 12. Arao Y, Hakamata Y, Igarashi Y, Sato Y, Kayama F, Takahashi M, Kobayashi E, Murakami T. Characterization of hepatic sexual dimorphism in Alb-DsRed2 transgenic rats. Biochem Biophys Res Commun 382: 46-50, 2009 13. Takahashi M, Izawa A, Ishigatsubo Y, Fujimoto K, Miyamoto M, Horie T, Aizawa Y, Amano J, Minota S, Murohara T, Matsubara H, Ikeda U. Therapeutic neovascularization by the implantation of autologous mononuclear cells in patients with connective tissue diseases. Curr Pharm Design 15: 2778-2783, 2009 14. Kadouchi I, Sakamoto K, Tangjiao L, Murakami T, Kobayashi E, Hoshino Y, Yamaguchi Y. Latexin is involed in bone morphogentic protein-2-induced chondrocyte differentiation. Biochem Biophys Res Commun. 378: 600-4, 2009 15. Horie M, Sekiya I, Muneta T, Ichinose S, Matsumoto K, Saito H, Murakami T, Kobayashi E. Intra-articular injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. Stem Cells 27: 878-887, 2009 16. Endo T, Ajiki T, Inoue H, Kikuchi M, Yashiro T, Nakama T, Hoshino Y, Murakami T, Kobayashi E. Implication of a neuropathic pain by enforced stepping exercise with aberrant axonal sprouting through brain-derived neurotrophic factor. Biochem Biophys Res Commun 381: 339-44, 2009 17. Yanagisawa S, Kadouchi I, Yokomori K, Hirose M, Hakozaki M, Hojo H, Maeda K, Kobayashi E, Murakami T. Identification and metastatic potential of tumor-initiating cells in malignant rhabdoid tumor of the kidney. Clin Cancer Res 5: 3014-22, 2009 18. Kawarasaki T, Uchiyama K, Hirao A, Azuma S, Otake M, Shibata M, Tsuchiya S, Enosawa S, Takeuchi K, Konno K, Yoshino H, Hakamata Y, Wakai T, Ookawara S, Tanaka H, Kobayashi E, Murakami T. Profile of new green fluorescent protein (GFP)-transgenic Jinhua pigs as an imaging source. J Biomed Opt 5(4): 054017, 2009 2008 1. Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, J Sagara, Nakayama J, Taniguchi S, Ikeda U. Critical role of bone marrow-derived ASC, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice. Circulation 117: 3079-3087, 2008 2. Morimoto H, Hirose M, Takahashi M, Kawaguchi M, Ise H, Kolattukudy PE, Yamada M, Ikeda U. MCP-1 induces cardioprotection against ischemia/reperfusion injury: Role of reactive oxygen species. Cardiovasc Res 78: 554-562, 2008 3. Takahashi M. High-mobility group box 1 protein (HMBG1) in ischemic heart disease: beneficial or deleterious. (Editorial) Cardiovasc Res 80: 5-6, 2008 4. Murayama H, Takahashi M, Takamoto M, Shiba Y, Ise H, Koyama J, Tagawa Y, Iwakura Y, Ikeda U. Deficiency of tumor necrosis factor-alpha and interferon-gamma in bone marrow cells synergistically inhibits neointimal formation following vascular injury. Cardiovasc Res 80: 175-180, 2008 5. Kubota K, Soeda J, Misawa R, Mihara M, Miwa S, Ise H, Takahashi M, Miyagawa S. Bone marrow-derived cell fuses with hepatic oval cells but are not involved in hepatic tumorgenesis in the choline-deficient ethionine-supplemented diet rat model. Carcinogenesis 29: 448-454, 2008 6. Hongo M, Tsutsui H, Mawatari E, Hidaka H, Kumazaki S, Yazaki Y, Takahashi M, Kinoshita O, Ikeda U. Fluvastatin improves arterial stiffness in patients with coronary artery diseases and hyperlipidemia: A 5-year follow-up study. Circ J 72: 722-728, 2008 7. Zenimaru Y, Takahashi S, Takahashi M, Yamada K, Iwasaki T, Hattori H, Imagawa M, Ueno M, Suzuki J, Miyamori I. Glucose deprivation accelerates VLDL receptor-mediated TG-rich lipoprotein uptake by AMPK activation in skeletal muscle cells. Biochem Biophys Res Commun 368: 716-722, 2008 8. Hosoya A, Ninomiya T, Hiraga T, Zhao C, Yoshiba K, Yoshiba N, Takahashi M, Okabe T, Wakitani S, Yamada H, Kasahara E, Ozawa H, Nakamura H. Alveolar bone regeneration of subcutaneously transplanted rat molar. Bone 42: 350-357, 2008 9. Murakami T, Sato A, Chun NAL, Hara M, Naito Y, Kobayashi Y, Kano Y, Furukawa Y, Kobayashi E. Transcriptional modulation using HDACi depsipeptide promotes immune cell-mediated tumor destruction of murine B16 melanoma. J Invest Dermatol 28: 1506-1516, 2008 10. Shiba Y, Takahashi M, Ikeda U. Models for the study of angiogenesis. Curr Pharm Design 14, 2008 2007 1. Shiba, Takahashi M, Yoshioka T, Yajima N, Morimoto H, Izawa A, Ise H, Hatake K, Motoyoshi K, Ikeda U. M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: The critical role of the SDF-1?CXCR4 system. Arterioscler Thromb Vasc Biol 27: 283-289, 2007 2. Morimoto H, Takahashi M, Shiba Y, Izawa A, Ise H, Hongo M, Hatake K, Motoyoshi K, Ikeda U. Bone marrow-derived CXCR4+ cells mobilized by M-CSF participate in the prevention of cardiac dysfunction and remodeling after myocardial infarction in mice. Am J Pathol 171: 755-766, 2007 3. Ogawa R, Takahashi M, Hirose S, Morimoto H, Ise H, Murakami T, Yasue T, Kuriyama K, Hongo M, Kobayashi E, Ikeda U. A novel sphingosine-1-phosphate receptor agonist KRP-203 attenuates rat autoimmune myocarditis. Biochem Biophys Res Commun 361: 621-628, 2007 4. Ito T, Okada T, Mimuro J, Miyashita H, Uchibori R, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Sakata Y, Shimada K, Ozawa K. Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats. Hypertension 50: 531-536, 2007 5. Hirose S, Takahashi M, Ogawa R, Morimoto H, Izawa A, Sato H, Ise H, Hongo M, Ikeda U. Erythropoietin attenuates the development of experimental autoimmune myocarditis. Cardiovasc Drug Ther 21: 17-27, 2007 6. Ito T, Okada T, Miyashita H, Nemoto T, Nonaka-Sarukawa M, Uchibori R, Maeda Y, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Shimada K, Ozawa K. Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats. Circ Res 101: 734-741, 2007 7. Izawa A, Ueno T, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R. Importance of donor- and recipient-derived selectins in cardiac allograft rejection. J Am Soc Nephrol 18: 2929-2936, 2007 8. Mawatari E, Hongo M, Sakai A, Terasawa F, Takahashi M, Yazaki Y, Kinoshita O, Ikeda U. Amlodipine prevents monocrotaline-induced pulmonary arterial hypertension and prolongs survival in rats independent of blood pressure lowering. Clin Exp Pharmacol Physiol 34: 594-600, 2007 9. Aso S, Ise H, Takahashi M, Kobayashi S, Morimoto H, Izawa A, Goto M, Ikeda U. Effective uptake of N-acetylglucosamine-conjugated liposome by cardiomyocytes in vitro. J Control Release 122: 189-198, 2007 10. Hosoya A, Nakamura H, Ninomiya T, Hoshi K, Yoshiba K, Yoshiba N, Takahashi M, Okabe T, Sahara N, Yamada H, Kasahara E, Ozawa . Hard tissue formation in subcutaneously transplanted rat dental pulp. J Dent Res 86: 469-474, 2007 11. Zhao C, Hosoya A, Kurita H, Hu T, Hiraga T, Ninomiya T, Yoshiba K, Yoshiba N, Takahashi M, Kurashina K, Ozawa H, Nakamura H. Immunohistochemical study of hard tissue formation in the rat pulp cavity after tooth replantation. Arch Oral Biol 52: 945-953, 2007 12. Kimura A, Ohmori T, Ohkawa R, Madoiwa S, Mimuro J, Murakami T, Kobayashi E, Hoshino Y, Yatomi Y, Sakata Y. Essential Roles of Sphingosine 1-phosphate/1P1 Receptor Axis in the Migration of Neural Stem Cells toward a Site of Spinal Cord Injury. Stem Cells 25: 115-124, 2007 13. Kakinuma T, Nadiminti H, Lonsdorf AS, Murakami T, Perez BA, Kobayashi H, Finkelstein SE, Pothiawala G, Belkaid Y, Hwang ST. Small numbers of residual tumor cells at the site of primary inoculation are critical for anti-tumor immunity following challenge at a secondary location. Cancer Immunol Immunother 56: 1119-1131, 2007 14. Ohsawa I, Uemoto S, Kobayashi E, Murakami T. Control of cyclosporine A-induced tumor progression using 15-Deoxyspergualin for rat cardiac transplantation. Transplantation 84: 424-428, 2007 15. Kobayashi M, Okada T, Murakami T, Ozawa O, Kobayashi E, Morita T. Tissue-targeted in vivo gene transfer coupled with histone deacetylase inhibitor depsipeptide (FK228) enhances adenoviral infection in rat renal cancer allograft model systems. Urology 70: 1230-1236, 2007 2006 1. Morimoto H, Takahashi M, Izawa A, Ise H, Hongo M, Kolattukudy PE, Ikeda U. Cardiac overexpression of MCP-1 in transgenic mice prevents cardiac dysfunction and remodeling after myocardial infarction. Circ Res 99:891-899, 2006 2. Yoshioka T, Takahashi M, Shiba Y, Suzuki C, Morimoto H, Izawa A, Ise H, Ikeda U. Granulocyte colony-stimulating factor accelerates reendothelialization and reduces neointimal formation after vascular injury in mice. Cardiovasc Res 70: 61-69, 2006 3. Takahashi M. The role of endothelin-1 in vascular remodeling in vivo. (Editorial) Cardiovasc Res 71: 4-5, 2006 4. Jia L, Takahashi M, Morimoto H, Takahashi S, Izawa A, Ise H, Iwasaki T, Hattori H, K-J. Wu, Ikeda U. Changes in cardiac lipid metabolism during sepsis: the essential role of very low-density lipoprotein receptors. Cardiovasc Res 69: 545-555, 2006 5. Suzuki C, Takahashi M, Morimoto H, Izawa A, Ise H, Hongo M, Hoshikawa Y, Ito T, Miyashita H, Kobayashi E, Shimada K, Ikeda U. Mycophenolate mofetil attenuates pulmonary arterial hypertension in rats. Biochem Biophys Res Commun 349: 781-788, 2006 6. Suzuki C, Takahashi M, Morimoto H, Izawa A, Ise H, Fujishiro J, Murakami T, Ishiyama J, Nakada A, Nakayama J, Ikeda U, Kobayashi E. Efficacy of mycophenolic acid combined with a novel immunomodulator KRP-203 in rat heart transplantation models. J Heart Lung Transpl 25: 302-309, 2006 7. Okada T, Uchibori R, Iwata-Okada M, Takahashi M, Nomoto T, Nonaka-Sarukawa M, Ito T, Liu Y, Mizukami H, Kume A, Kobayashi E, Ozawa K. A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells. Mol Ther 13: 738-746, 2006 8. Sato H, Takahashi M, Ise H, Yamada A, Hirose S, Tagawa Y, Morimoto H, Izawa A, Ikeda U. Collagen synthesis is required for ascorbic acid-enhanced differentiation of mouse embryonic stem cells into cardiomyocytes. Biochem Biophys Res Commun 342: 107-112, 2006 9. Misawa R, Ise H, Takahashi M, Morimoto H, Kobayashi E, Miyagawa S, Ikeda U. Development of liver regenerative therapy using glycoside-modified bone marrow cells. Biochem Biophys Res Commun 342: 434-440, 2006 10. Fujishiro J, Suzuki C, Kudoh S, Yasue T, Hakamata Y, Takahashi M, Murakami T, Hashizume K, Kobayashi E. Conversion from cyclosporine A to mycophenolic acid with a sphingosine-1-phosphate receptor agonist, KRP-203, reverses host nephrotoxicity and prevents transplant arteriosclerosis. J Heart Lung Transpl 25: 825-833. 2006 11. Kaneko T, Murakami T, Kawana H, Takahashi M, Yasue T, Kobayashi E. Shingosine-1-phosphate receptor agonists suppress concanavalin A-induced hepatic injury in mice. Biochem Biophys Res Commun 345: 85-92, 2006 12. Fujishiro J, Kudou S, Iwai S, Takahashi M, Hakamata Y, Kinoshita M, Iwanami S, Izawa S, Yasue T, Murakami T, Hashizume K, Kobayashi E. Use of sphingosine-1-phosphate (S1P) receptor agonist, KRP-203, in combination with a subtherapeutic dose of cyclosporine A for rat renal transplantation. Transplantation 82: 804-812, 2006 13. Izawa A, Sano K, Takehara M, Inobe M, Suzuki J, Inamura H, Takahashi M, Ikeda U, Isobe M, Uede T. Cre/loxP-mediated CTLA4IgG gene transfer induces clinically relevant immunosuppression via of-off gene recombination in vivo. Cardiovasc Res 69: 289-297, 2006 14. Arao Y, Hakamata Y, Igarashi Y, Sato Y, Murakami T, Kobayashi E. Bioimaging of DsRed fluorescence in transgenic rat liver. Progr Biomed Opt Imaging 7: 60980E (1-7), 2006 15. Hakamata Y, Igarashi Y, Murakami T, Kobayashi E. Progression of GFP-expressed skin graft after intrathymic injection of GFP positive splenocytes in adult rat. Progr Biomed Opt Imaging 7: 60980F (1-8), 2006 16. Kobayashi Y, Ohtsuki M, Murakami T, Kobayashi T, Sutheesophon K, Kitayama H, Kano Y, Kusano E, Nakagawa H, Furukawa Y. Histone deacetylase inhibitor depsipeptide (FK228) suppresses the Ras-MAP kinase signaling pathway by up-regulation Rap1 and induces apoptosis in malignant melanoma. Oncogene 25: 512-24, 2006 17. Cardones AR, Leitner WW, Murakami T, Kapoor V, Udey MC, Hwang ST. Genetic immunization with LYVE-1 cDNA yields function-blocking antibodies against native protein. Microvasc Res 71: 32-39, 2006 18. Hakamata Y, Murakami T, Kobayashi E. “Firefly rats” as an organ/cellular source for long-term in vivo bioluminescent imaging. Transplantation 81: 1179-1184 19. Ohsawa I, Murakami T, Uemoto S, Kobayashi E. In vivo luminescent imaging of cyclosporine A-mediated cancer progression in rats. Transplantation 81: 1558-1567, 2006 20. Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T. Antitumor activity of interferon (IFN)-lambda in murine tumor models. J Immunol 2006; 176 (12): 7686-7694, 2006 2005 1. Shimizu H, Takahashi M, Kaneko T, Murakami T, Hakamata Y, Kudou S, Kishi T, Fukuchi K, Iwanami S, Kuriyama K, Yasue T, Enosawa S, Matsumoto K, Takeyoshi I, Morishita Y, Kobayashi E. KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts. Circulation 111: 222-229, 2005 2. Takahashi M, Takahashi S, Suzuki C, Jia L, Morimoto H, Ise H, Iwasaki T, Hattori H, Zenimaru Y, Suzuki J, Miyamori I, Kobayashi E, Ikeda U. Interleukin-1beta attenuates uptake of beta-very low-density lipoprotein through downregulation of its receptor in vascular smooth muscle cells. J Mol Cell Cardiol 38: 637-646, 2005 3. Kamiyoshi Y, Takahashi M, Yokoseki O, Yazaki Y, Hirose S, Morimoto H, Watanabe N, Kinoshita O, Hongo M, Ikeda U. Mycophenolate mofetil prevents the development of experimental autoimmune myocarditis. J Mol Cell Cardiol 39:467-477, 2005 4. Takahashi M, Shimizu H, Murakami T, Enosawa S, Suzuki C, Takeno Y, Hakamata Y, Kudou S, Izawa S, Yasue T. Kobayashi E. A novel immunomodulator KRP-203 combined with cyclosporine A prolonged graft survival and abrogates transplant vasculopathy in rat heart allografts. Transplant Proc 37: 143-145, 2005 5. Yamaguchi Y, Kubo T, Murakami T, Takahashi M, Hakamata Y, Kobayashi E, Yoshida S, Hosokawa K, Yoshikawa K, Itami S. Bone marrow cells differentiate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing. Brit J Dermatol 152: 616-622, 2005 6. Tahara K, Murakami T, Fujishiro J, Takahahshi M, Inoue S, Hashizume K, Matsuno K, Kobayashi E. Regeneration of the rat neonatal intestine in transplantation. Ann Surg 242: 124-132, 2005 7. Suzuki F, Hashikura Y, Ise H, Ishida A, Nakayama J, Takahashi M, Miyagawa S, Ikeda U. MCI-186 (Edaravone), a free radical scavenger, attenuates liver ishemica-reperfusion injury rats. Transpl Int 18: 844-853, 2005 8. Sato Y, Matsui K, Ajiki T, Igarashi Y, Takahashi M, Murakami T, Hakamata Y, Tabata Y, Kobayashi E. Can a bone marrow cell contribute to organ regeneration? In vivo analysis using transgenic rats with reporter genes. Transplant Proc 37: 273-275, 2005 9. Fujishiro J, Takeda S, Takeno Y, Takeuchi K, Ogata Y, Takahashi M, Hakamata Y, Murakami T, Okada T, Ozawa K, Hashizume K, Kobayashi E. Gene transfer to the rat kidney in vivo and ex vivo using an adenovirus vector: factor influencing transgene expression. Nephrol Dial Transplant 20: 1385-1391, 2005 10. Inoue H, Ohsawa I, Murakami T, Kimura A, Hakamata Y, Sato Y, Kaneko T, Takahashi M, Okada T, Ozawa K, Francis J, Leone P, Kobayashi E. Development of new inbred transgenic strains of rats with LacZ or GFP. Biochem Biophys Res Commun 329: 288-295, 2005 11. Sato Y, Ajiki T, Inoue S, Fujishiro J, Yoshino H, Igarashi Y, Hakamata Y, Kaneko T, Murakami T, Kobayashi E. Gene silencing in rat-liver and limb grafts by rapid injection of small interference RNA. Transplantation 79: 240-243, 2005 12. Fujishiro J, Kawana H, Inoue S, Shimizu H, Yoshino H, Hakamata Y, Kaneko T, Murakami T, Hashizume K, Kobayashi E. Efficiency of adenovirus-mediated gene transduction in heart grafts in rats. Transplant Proc 37: 67-9, 2005 13. Ajiki T, Kimura A, Sato Y, Murakami T, Hakamata Y, Kariya Y, Hoshino Y, Kobayashi E. Composite tissue transplantation in rats: Fusion of donor muscle to the recipient site. Transplant Proc 37: 208-9, 2005 14. Kimura A, Ajiki T, Takeuchi Y, Hakamata Y, Murakami T, Hoshino Y, Kobayashi E. Transmigration of donor cells involved in the sciatic nerve graft. Transplant Proc 37: 205-207, 2005 15. Murakami T, Inoue S, Sato Y, Ajiki T, Ohsawa I, Kobayashi E. Genetic modification in organ transplantation and in vivo luciferase imaging. Progr Biomed Opt Imaging 6: 169-176, 2005 16. Ameen M, Allen MH, Fisher SA, Lewis CM, Cuthbert A, Kondeatis E, Vaughan RW, Murakami T, Nakagawa H, Barker JN. Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations. Clin Exp Dermatol 30: 414-418, 2005 17. Sereemaspun A, Takeuchi K, Sato Y, Iwamoto S, Inagaki T, Ookawara S, Hakamata Y, Murakami T, Kobayashi E. Testosterone-dependent transgene expression in the liver of the CAG-lacZ transgenic rat. Gene Expr 12: 305-313, 2005 　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　ページトップへ戻る