{"id":1094,"date":"2020-09-10T15:54:10","date_gmt":"2020-09-10T06:54:10","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/cms\/?p=1094"},"modified":"2020-09-10T15:54:10","modified_gmt":"2020-09-10T06:54:10","slug":"%e6%8a%84%e8%aa%ad%e4%bc%9a%e3%80%802020%e5%b9%b49%e6%9c%8810%e6%97%a5","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/reading-session\/%e6%8a%84%e8%aa%ad%e4%bc%9a%e3%80%802020%e5%b9%b49%e6%9c%8810%e6%97%a5\/","title":{"rendered":"\u6284\u8aad\u4f1a\u30002020\u5e749\u670810\u65e5"},"content":{"rendered":"<p><span style=\"font-size: 11pt;\">\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u5b66\u3067\u306f\u6bce\u9031\u533b\u5c40\u54e1\u304c\u4ea4\u4ee3\u3067\u6284\u8aad\u4f1a\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 11pt; color: #000080;\">Six\u2010month flare risk after discontinuing long\u2010term methotrexate treatment in patients having rheumatoid arthritis with low disease activity.<\/span><br \/>\n<span style=\"font-size: 11pt; color: #000080;\">Int J Rheum Dis (online)<\/span><\/p>\n<p><span style=\"font-size: 11pt; color: #000080;\"><strong>\u76ee\u7684<\/strong>\uff1a\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\uff08MTX\uff09\u306b\u3088\u308a\u4f4e\u75be\u60a3\u6d3b\u52d5\u6027\uff08LDA\uff09\u3092\u9054\u6210\u3057\u305f\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff08RA\uff09\u60a3\u8005\u306e\u518d\u71c3\u7387\u3068\u305d\u306e\u518d\u71c3\u306b\u95a2\u4e0e\u3059\u308b\u8981\u56e0\u3092\u691c\u8a0e\u3059\u308b\u3002<\/span><br \/>\n<span style=\"font-size: 11pt; color: #000080;\"><strong>\u65b9\u6cd5<\/strong>\uff1a\u5f8c\u65b9\u8996\u7684\u306b\u3001MTX\u309210\u5e74\u4ee5\u4e0a\u670d\u7528\u3057\u3001LDA\u307e\u305f\u306f\u5bdb\u89e3\u72b6\u614b\u306eRA\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3002\u518d\u71c3\u3068\u306f\u3001MTX\u4e2d\u6b62\u5f8c\u534a\u5e74\u4ee5\u5185\u306b\u3001DAS28-ESR\uff1e1.2\u4ee5\u4e0a\u3068\u3057\u305f\u3002<\/span><br \/>\n<span style=\"font-size: 11pt; color: #000080;\"><strong>\u7d50\u679c<\/strong>\uff1a\u5408\u8a0897\u4eba\u306eRA\u60a3\u8005\u3002\u5e73\u5747DAS28-ESR 1.96\u00b10.56\u3001MTX\u7dcf\u6295\u4e0e\u91cf11.7g\uff08\u4e2d\u592e\u5024\uff09\u3001MTX\u670d\u7528\u671f\u959319\u5e74\uff08\u4e2d\u592e\u5024\uff09\u3002\u518d\u71c3\u306f43\u4eba\uff0844.3\uff05\uff09\u306b\u307f\u3089\u308c\u3001\u518d\u71c3\u307e\u3067\u306e\u4e2d\u592e\u5024\u306f99\u65e5\uff0828-168)\u65e5\u3002\u5358\u5909\u91cf\u89e3\u6790\u3067\u306f\u3001\u4e2d\u6b62\u6642\u306eCRP\u3001\u4e2d\u6b62\u6642\u306eESR\u3001\u4e2d\u6b62\u524d\u534a\u5e74\u9593\u306e\u5e73\u5747ESR\u3001\u4e2d\u6b62\u524d\u306eMTX\u6295\u4e0e\u91cf\u3001\u4ed6\u306e\u5408\u6210DMARD\u4f75\u7528\u304c\u518d\u71c3\u3068\u95a2\u9023\u3057\u305f\u3002\u591a\u5909\u91cf\u89e3\u6790\u3067\u306f\u3001\u4e2d\u6b62\u524d\u306eMTX\u6295\u4e0e\u91cf\u304c\u518d\u71c3\u3068\u95a2\u9023\u3057\u305f\uff08OR 1.014, CI 1.014-1.342;<br \/>\nP= 0.031)\u3002<\/span><br \/>\n<span style=\"font-size: 11pt; color: #000080;\"><strong>\u7d50\u8ad6<\/strong>\uff1a\u9577\u671fMTX\u6cbb\u7642\u306b\u3088\u308aLDA\u3092\u9054\u6210\u3057\u3066\u3044\u308b\u60a3\u8005\u3067\u306f\u3001\u534a\u6570\u4ee5\u4e0a\u306e\u60a3\u8005\u304c\u518d\u767a\u3057\u306a\u304b\u3063\u305f\u3002MTX\u4e2d\u6b62\u524d\u306e\u3001\u3088\u308a\u591a\u3044MTX\u6295\u4e0e\u91cf\u304c\u9ad8\u3044\u518d\u767a\u7387\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u3002<\/span><\/p>\n<p><span style=\"font-size: 11pt; color: #000080;\">\u30d0\u30a4\u30aa\u88fd\u5264\u3084JAKi\u3092\u4f75\u7528\u3057\u3066\u3044\u308b\u60a3\u8005\u304c2\u5272\u5f31\u542b\u307e\u308c\u3001\u89b3\u5bdf\u671f\u9593\u304c6\u30ab\u6708\u3068\u77ed\u3044\u3067\u3059\u304c\u3001\u9577\u671f\u5bdb\u89e3\u60a3\u8005\u306a\u30891\/3\u7a0b\u5ea6\u306fMTX\u30d5\u30ea\u30fc\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u8a66\u3057\u3066\u3082\u3088\u3055\u305d\u3046\u3067\u3059\u3002<\/span><\/p>\n<p style=\"text-align: right;\"><span style=\"font-size: 11pt; color: #000080;\">\u62c5\u5f53\u3000\uff2e<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u5b66\u3067\u306f\u6bce\u9031\u533b\u5c40\u54e1\u304c\u4ea4\u4ee3\u3067\u6284\u8aad\u4f1a\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002 Six\u2010month flare risk after discontinuing long\u2010term methotrexate treatme &#8230;","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-1094","post","type-post","status-publish","format-standard","hentry","category-reading-session"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1094","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=1094"}],"version-history":[{"count":0,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1094\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=1094"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=1094"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=1094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}