{"id":1297,"date":"2020-12-08T10:01:18","date_gmt":"2020-12-08T01:01:18","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/cms\/?p=1297"},"modified":"2021-03-25T17:29:57","modified_gmt":"2021-03-25T08:29:57","slug":"%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-31%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b67%e3%80%80-thoc%e7%99%ba%e8%a6%8b%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-31%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b67%e3%80%80-thoc%e7%99%ba%e8%a6%8b%ef%bc%81\/","title":{"rendered":"\u79c1\u7684\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (31)\u3000\u7834\u9aa8\u7d30\u80de\u7814\u7a76(7)\u3000\u201c ThOc\u201d\u767a\u898b\uff01\uff1f"},"content":{"rendered":"<p><span style=\"font-size: 12pt; color: #000080;\">Th1\u7d30\u80de\u306f\u3001CD4\u967d\u6027T\u7d30\u80de\u3092\u523a\u6fc0\u3059\u308b\u3068\u304d\u306bIL-12\u3092\u52a0\u3048\u3001\u307e\u305fIL-4\u3092\u4e2d\u548c\u3059\u308b\u305f\u3081\u306b\u6297IL-4\u6297\u4f53\u3092\u52a0\u3048\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8a66\u9a13\u7ba1\u5185\u3067\u5206\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002IL-12\u306e\u4ee3\u308f\u308a\u306bIL-23\u3092\u52a0\u3048\u308c\u3070\u3001IFN-\u03b3\u306e\u4ee3\u308f\u308a\u306bIL-17\u3092\u7523\u751f\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3002\u307e\u305f\u3053\u3053\u3067\u3001\u6297IL-4\u6297\u4f53\u3060\u3051\u3067\u306f\u306a\u304f\u6297IFN-\u03b3\u6297\u4f53\u3082\u52a0\u3048\u308b\u3068\u3044\u3046\u5de5\u592b\u3092\u4ed8\u3051\u52a0\u3048\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u5fc5\u9808\u3067\u306f\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001IFN-\u03b3\u81ea\u4f53\u306bTh1\u5206\u5316\u3092\u4fc3\u9032\u3059\u308b\u50cd\u304d\u304c\u3042\u308b\u305f\u3081\uff08\u2192<a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-8%e3%80%80%e3%83%ab%e3%82%b7%e3%83%95%e3%82%a7%e3%83%a9%e3%83%bc%e3%82%bc%e3%82%a2%e3%83%83%e3%82%bb\">\u3053\u3068\u306f\u3058\u30818<\/a>\uff09\u3001\u4e2d\u548c\u3057\u3066\u304a\u304f\u306b\u3053\u3057\u305f\u3053\u3068\u306f\u306a\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3057\u305f\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt; 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color: #000080;\">\u6211\u3005\u306f\u30e9\u30dc\u5185\u3067\u3053\u306eTh\u7d30\u80de\u30b5\u30d6\u30bb\u30c3\u30c8\u306e\u3053\u3068\u3092ThOc\u3064\u307e\u308a\u7834\u9aa8\u7d30\u80de(OsteoClast)\u3092\u8a98\u5c0e\u3059\u308bTh\u7d30\u80de\u3068\u547c\u3093\u3067\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u5927\u304d\u306a\u61f8\u5ff5\u3068\u3057\u3066\u3001Th1\/Th2\u30d1\u30e9\u30c0\u30a4\u30e0\u306b\u53cd\u65d7\u3092\u7ffb\u3059\u3088\u3046\u306a\u3053\u3093\u306a\u30b3\u30f3\u30bb\u30d7\u30c8\u3092\u3001\u679c\u305f\u3057\u3066\u4fe1\u3058\u3066\u8cb0\u3048\u308b\u306e\u304b\uff1f\u3068\u3044\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u305d\u3082\u305d\u3082\u81ea\u5206\u81ea\u8eab\u3082\u534a\u4fe1\u534a\u7591\u3060\u3063\u305f\u8a33\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\">\u30b3\u30f3\u30bb\u30d7\u30c8\u306e\u59a5\u5f53\u6027\u3092\u88dc\u5f37\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3068\u8003\u3048\u3001\u3044\u304f\u3064\u304b\u306e\u907a\u4f1d\u5b50\u6539\u5909\u30de\u30a6\u30b9\u3092\u6d77\u5916\u306a\u3069\u304b\u3089\u624b\u306b\u5165\u308c\u3066\u5b9f\u9a13\u3057\u3066\u3044\u308b\u6700\u4e2d\u306b\u5927\u5909\u306a\u3053\u3068\u304c\u7d9a\u3051\u3056\u307e\u306b\u8d77\u304d\u307e\u3057\u305f\u3002<\/span><\/p>\n<p style=\"text-align: right;\"><span style=\"font-size: 12pt; color: #808080;\"><strong>\u4f50\u85e4\u3000\u6d69\u4e8c\u90ce<\/strong><\/span><\/p>\n<p style=\"text-align: right;\"><span style=\"font-size: 11pt;\"><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-30%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b66%e3%80%80%e3%83%91%e3%83%a9%e3%83%89\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (30)<\/a>\u00a0\u00a0<strong><em><span style=\"color: #0000ff;\">\u2190 Prev\u3000\u3000\u3000\u3000\u3000<\/span><span style=\"color: #0000ff;\">Next \u2192<\/span><\/em><\/strong><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-32%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b68%e3%80%80th17%e7%b4%b0%e8%83%9e\"><span style=\"color: #000080;\"><span style=\"font-size: 11pt;\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (32)<\/span><\/span><\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"Th1\u7d30\u80de\u306f\u3001CD4\u967d\u6027T\u7d30\u80de\u3092\u523a\u6fc0\u3059\u308b\u3068\u304d\u306bIL-12\u3092\u52a0\u3048\u3001\u307e\u305fIL-4\u3092\u4e2d\u548c\u3059\u308b\u305f\u3081\u306b\u6297IL-4\u6297\u4f53\u3092\u52a0\u3048\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8a66\u9a13\u7ba1\u5185\u3067\u5206\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002IL-12\u306e\u4ee3\u308f\u308a\u306bIL-23\u3092\u52a0\u3048\u308c\u3070\u3001IFN-\u03b3\u306e\u4ee3\u308f &#8230;","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-1297","post","type-post","status-publish","format-standard","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1297","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=1297"}],"version-history":[{"count":1,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1297\/revisions"}],"predecessor-version":[{"id":1538,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1297\/revisions\/1538"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=1297"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=1297"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=1297"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}