{"id":1383,"date":"2021-01-18T13:36:25","date_gmt":"2021-01-18T04:36:25","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/cms\/?p=1383"},"modified":"2021-03-25T17:29:56","modified_gmt":"2021-03-25T08:29:56","slug":"%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-34%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b610-%e8%ac%8e%e3%81%af%e3%82%80%e3%81%97","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-34%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b610-%e8%ac%8e%e3%81%af%e3%82%80%e3%81%97\/","title":{"rendered":"\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (34)\u3000\u7834\u9aa8\u7d30\u80de\u7814\u7a76(10) \u8b0e\u306f\u3080\u3057\u308d\u5897\u3048\u305f"},"content":{"rendered":"<p><span style=\"color: #000080; font-size: 12pt;\"><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/1f698c52768e2b26380c12163010f646.png\" rel=\"lightbox[1383]\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-1340 alignright\" src=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/1f698c52768e2b26380c12163010f646.png\" alt=\"\" width=\"350\" height=\"194\" srcset=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/1f698c52768e2b26380c12163010f646.png 469w, https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/1f698c52768e2b26380c12163010f646-300x166.png 300w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><\/a>\u3000Th17\u7814\u7a76\u306f2006\u5e74\u4ee5\u964d\u3082\u6025\u901f\u306b\u9032\u307f\u307e\u3057\u305f\u3002\u53f3\u306e\u30b0\u30e9\u30d5\u306fPuibMed\u3067<\/span><span style=\"color: #000080; font-size: 12pt;\">Th17\u3092\u691c\u7d22\u3057\u305f\u7d50\u679c\u3067\u3059\u3002\u4eca\u3067\u306f\u6bce\u5e741000\u4ee5\u4e0a\u306e\u8ad6\u6587\u304cpublish\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000080; font-size: 12pt;\">\u3053\u306e2006\u5e74\u306eJ Exp Med\u8a8c\u306b\u5831\u544a\u3057\u305f\u7814\u7a76\u306f\u79c1\u306b\u3068\u3063\u3066\u5927\u5909\u9762\u767d\u3044\u3082\u306e\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u540c\u6642\u306b\u3001\u7b54\u3048\u3092\u51fa\u3057\u305f\u4ee5\u4e0a\u306b\u3001\u5206\u304b\u3089\u306a\u3044\u3053\u3068\u304c\u3044\u3063\u305d\u3046\u5897\u3048\u305f\u6642\u671f\u3067\u3082\u3042\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u3044\u304f\u3064\u304b\u3092\u6319\u3052\u308b\u3068\u3001<\/span><\/p>\n<ol>\n<li><span style=\"color: #000080; font-size: 12pt;\">IFN-\u03b3\u306f\u78ba\u304b\u306b\u7834\u9aa8\u7d30\u80de\u5206\u5316\u3092\u5f37\u529b\u306b\u6291\u5236\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u60a3\u8005\u3055\u3093\u306e\u95a2\u7bc0\u6db2\u3092\u63a1\u53d6\u3059\u308b\u3068IFN-\u03b3\u306f\u7d50\u69cb\u5b58\u5728\u3059\u308b\u306e\u3067\u3059\u3002\u3069\u3046\u3057\u3066\u305d\u3093\u306a\u5834\u6240\u3067\u7834\u9aa8\u7d30\u80de\u304c\u5206\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u304b\u3002\uff11\u3064\u306e\u4eee\u8aac\u3068\u3057\u3066\u306f\u3001<u>\u30d2\u30c8\u3067\u3082IFN-\u03b3\u304c\u7834\u9aa8\u7d30\u80de\u5206\u5316\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u306f\u5206\u304b\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u304c\u3001\u30de\u30a6\u30b9\u306b\u6bd4\u3079\u3066\u305d\u306e\u7a0b\u5ea6\u304c\u5f31\u3044\u306e\u304b\u3082\u3057\u308c\u306a\u3044<\/u>\u3001\u3068\u3044\u3046\u3053\u3068\u3092\u8003\u3048\u307e\u3057\u305f\u3002<\/span><\/li>\n<li><span style=\"color: #000080; font-size: 12pt;\">\u3053\u306e\u7814\u7a76\u306f\u3001\u5143\u3005\u3001\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u304cTh1\u578b\u306e\u75be\u60a3\u3067\u306f\u306a\u3044\u306e\u3067\u306f\u306a\u3044\u304b\u3001\u3068\u3044\u3046\u6240\u304b\u3089\u51fa\u767a\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u304c\u3001\u3067\u306f<u>\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306fTh17\u578b\u306e\u75be\u60a3\u3068\u8a00\u3048\u308b\u306e\u3067\u3057\u3087\u3046\u304b<\/u>\u3002<\/span><\/li>\n<li><span style=\"color: #000080; font-size: 12pt;\">\u4e0b\u306e\u56f3\u306f\u3001\u8ad6\u6587\u306e\u6700\u5f8c\u306b\u793a\u3057\u305f\u6982\u5ff5\u56f3\u3067\u3059\u3002\u3053\u3053\u3067\u3001<u>\u6ed1\u819c\u306e\u7dda\u7dad\u82bd\u7d30\u80de\u304cIL-17\u306e\u4f5c\u7528\u3067\u7834\u9aa8\u7d30\u80de\u5206\u5316\u56e0\u5b50RANKL\u3092\u767a\u73fe\u3059\u308b\u3088\u3046\u306a\u7d75\u3092\u63cf\u3044\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u8a3c\u62e0\u306f\u5168\u304f\u7121\u304f\u3001\u3053\u306e\u6642\u70b9\u3067\u306f\u4eee\u8aac\u306b\u904e\u304e\u307e\u305b\u3093\u3067\u3057\u305f<\/u>\u3002\u3053\u308c\u306f\u30d2\u30c8\u306e\u7d30\u80de\u3092\u4f7f\u3063\u3066\u691c\u8a3c\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u5bbf\u984c\u3068\u3057\u3066\u6b8b\u3063\u3066\u3044\u307e\u3057\u305f\u3002<a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/0a48911295350ff2449b7f76a4a94d2c.png\" rel=\"lightbox[1383]\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1375 alignleft\" src=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/0a48911295350ff2449b7f76a4a94d2c.png\" alt=\"\" width=\"346\" height=\"132\" srcset=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/0a48911295350ff2449b7f76a4a94d2c.png 346w, https:\/\/www.jichi.ac.jp\/alle\/cms\/wp-content\/uploads\/0a48911295350ff2449b7f76a4a94d2c-300x114.png 300w\" sizes=\"auto, (max-width: 346px) 100vw, 346px\" \/><\/a>\u5b9f\u306f\u30de\u30a6\u30b9\u306e\u9aa8\u82bd\u7d30\u80de\u306bIL-17\u3092\u3075\u308a\u304b\u3051\u3066\u3082\u3001\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u3068\u3044\u3046\u65b9\u6cd5\u3067RANKL\u306e\u767a\u73fe\u3092\u898b\u308b\u3053\u3068\u306f\u3067\u304d\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u3001<u>\u672c\u5f53\u306b\u77e5\u308a\u305f\u3044\u306e\u306f\u30d2\u30c8\u306e\u6ed1\u819c\u7dda\u7dad\u82bd\u7d30\u80de\u3067\u3069\u3046\u306a\u308b\u304b<\/u>\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/span><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #000080; font-size: 12pt;\">\u3053\u306e\u3088\u3046\u306b\u8272\u3005\u306a\u8b0e\u304c\u6b8b\u3063\u3066\u3044\u305f\u306e\u3067\u3059\u304c\u3001\u305d\u308c\u3092\u89e3\u6c7a\u3059\u308b\u306e\u306b\u306f\u3001\u57fa\u790e\u306e\u7814\u7a76\u5ba4\u3088\u308a\u3082\u3080\u3057\u308d\u81e8\u5e8a\u306e\u73fe\u5834\u306b\u623b\u3063\u305f\u65b9\u304c\u826f\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3053\u306e\u6642\u70b9\u3067\u79c1\u306f\u3001\u81ea\u5206\u306e\u9032\u8def\u306b\u3064\u3044\u3066\u60a9\u3080\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/span><\/p>\n<p style=\"text-align: right;\"><strong>\u4f50\u85e4\u3000\u6d69\u4e8c\u90ce<\/strong><\/p>\n<p style=\"text-align: right;\"><span style=\"font-size: 11pt;\"><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-33%e3%80%80%e7%a0%b4%e9%aa%a8%e7%b4%b0%e8%83%9e%e7%a0%94%e7%a9%b69%e3%80%80%e5%b9%bb%e3%81%aetho\"><span style=\"color: #000080;\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (33)<\/span><\/a>\u00a0\u00a0<strong><em><span style=\"color: #0000ff;\">\u2190 Prev\u3000\u3000\u3000\u3000\u3000<\/span><span style=\"font-size: 11pt; color: #0000ff;\">Next \u2192<\/span><\/em><\/strong><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-35%e3%80%80%e3%81%9d%e3%81%97%e3%81%a6%e5%a4%a7%e5%ad%a6%e7%97%85%e9%99%a2%e3%81%b81\"><span style=\"color: #000080;\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (35)<\/span><\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"\u3000Th17\u7814\u7a76\u306f2006\u5e74\u4ee5\u964d\u3082\u6025\u901f\u306b\u9032\u307f\u307e\u3057\u305f\u3002\u53f3\u306e\u30b0\u30e9\u30d5\u306fPuibMed\u3067Th17\u3092\u691c\u7d22\u3057\u305f\u7d50\u679c\u3067\u3059\u3002\u4eca\u3067\u306f\u6bce\u5e741000\u4ee5\u4e0a\u306e\u8ad6\u6587\u304cpublish\u3055\u308c\u3066\u3044\u307e\u3059\u3002 &nbsp; \u3053\u306e2006\u5e74\u306eJ Exp Med\u8a8c\u306b\u5831 &#8230;","protected":false},"author":2,"featured_media":1340,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-1383","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=1383"}],"version-history":[{"count":1,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1383\/revisions"}],"predecessor-version":[{"id":1530,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1383\/revisions\/1530"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media\/1340"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=1383"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=1383"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=1383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}