{"id":1707,"date":"2021-06-17T17:16:09","date_gmt":"2021-06-17T08:16:09","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/cms\/?p=1707"},"modified":"2021-06-25T17:14:43","modified_gmt":"2021-06-25T08:14:43","slug":"1707","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/reading-session\/1707\/","title":{"rendered":"\u6284\u8aad\u4f1a\u30002021\u5e746\u670817\u65e5"},"content":{"rendered":"

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Rheumatology (Oxford). 2021 May 14;60(5):2348-2354.
\n<\/span>Acute exacerbation of rheumatoid arthritis-associated interstitial lung disease: clinical features and prognosis<\/span><\/p>\n

\u76ee\u7684\uff1a<\/strong>\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306b\u4f34\u3046\u9593\u8cea\u6027\u80ba\u75be\u60a3\uff08RA-ILD\uff09\u306f\u6025\u6027\u5897\u60aa\uff08ILD-AE\uff09\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u3002<\/span>
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\n<\/span>
\n\u65b9\u6cd5\uff1a<\/strong>2007\u5e74\uff5e2019\u5e74\u306b\u5165\u9662\u3057\u305fRA-ILD\u60a3\u8005\uff08n=165)\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3002ILD-AE\u3092\u8d77\u3053\u3057\u305f
\n<\/span>\u60a3\u8005\u3068\u8d77\u3053\u3055\u306a\u304b\u3063\u305f\u60a3\u8005\u3092\u6bd4\u8f03\u3057\u3001ILE-AE\u306b\u95a2\u9023\u3059\u308b\u5371\u967a\u56e0\u5b50\u3092\u540c\u5b9a\u3057\u305f\u3002\u751f\u5b58\u3057\u305f\u60a3\u8005\u3068
\n<\/span>\u6b7b\u4ea1\u3057\u305f\u60a3\u8005\u306e\u7279\u5fb4\u3082\u6bd4\u8f03\u3057\u305f\u3002
\n<\/span><\/p>\n

\u7d50\u679c\uff1a<\/strong>\u60a3\u8005\u306e\u5e73\u5747\u5e74\u9f62\u300073.6\u6b73\u300197\u4eba\uff0871.9\uff05\uff09\u306f\u5973\u6027\u3060\u3063\u305f\u300230\u4eba\uff0822.2\uff05\uff09\u306e\u60a3\u8005\u304c
\nILD-AE\u3092<\/span>\u767a\u75c7\u3057\u300113\u4eba\uff0843.3\uff05\uff09\u304c\u6b7b\u4ea1\u3057\u305f\u3002\u591a\u5909\u91cf\u89e3\u6790\u3067\u306f\u3001usual interstitial pneumonia (UIP)\u30d1\u30bf\u30fc\u30f3<\/span>\u304cILD-AE\u3068\u95a2\u9023\u3057\u305f\uff08OR\u30002.55, 95%CI 1.05-6.20, P=0.038)\u3002Cox\u6bd4\u4f8b\u5206\u6790\u3067\u306fUIP\u30d1\u30bf\u30fc\u30f3\u304c\u6b7b\u4ea1\u3068<\/span>\u95a2\u9023\u3057\u305f\u304c\uff08HR 4.67, 95%CI 1.02-21.45, P=0.048\uff09\u3001MTX\u4f7f\u7528\u306f\u751f\u5b58\u3068\u95a2\u9023\u3057\u305f<\/span>\uff08HR 0.16\u300195%CI 0.04-0.72, P=0.016)\u3002<\/span><\/p>\n

\u7d50\u8ad6\uff1a<\/strong>UIP\u30d1\u30bf\u30fc\u30f3\u306fILD-AE\u306e\u767a\u75c7\u3068\u95a2\u9023\u3057\u3066\u3044\u305f\u3002UIP\u30d1\u30bf\u30fc\u30f3\u3001MTX\u975e\u4f7f\u7528\u304cILE-AE\u306e
\n\u6b7b\u4ea1\u3068<\/span>\u95a2\u9023\u3057\u305f\u3002<\/span><\/p>\n

\u611f\u60f3\uff1a<\/strong>ILD-AE\u306f\u3001\u7d04\u534a\u6570\u304c\u52a9\u304b\u3089\u306a\u3044\u3068\u3044\u3046\u306e\u306f\u59a5\u5f53\u306a\u6570\u5b57\u3067\u3059\u3002ILD\u306f\u753b\u50cf\u4e0a\u306e\u5e83\u304c\u308a\u3084
\n<\/span>\u80ba\u6a5f\u80fd\u306b\u3088\u3063\u3066\u91cd\u75c7\u5ea6\u306f\u7570\u306a\u308a\u307e\u3059\u3002MTX\u306e\u4f7f\u7528\u304c\u751f\u5b58\u3068\u95a2\u9023\u3057\u305f\u306e\u306f\u3001MTX\u304c\u4f7f\u7528\u3067\u304d\u308b\u3001<\/span>\u3082\u3068\u3082\u3068ILD\u304c\u8efd\u75c7\u306e\u60a3\u8005\u3060\u3063\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002RA\u60a3\u8005\u3067\u306f\u3001MTX\u4f7f\u7528\u8005\u304c\u611f\u67d3\u75c7\u304c
\n\u5c11\u306a\u3044\u3001<\/span>\u3068\u540c\u3058\u8003\u3048\u65b9\u3067\u3059\u3002<\/span><\/p>\n

\u62c5\u5f53\u3000\uff2e<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u5b66\u3067\u306f\u6bce\u9031\u533b\u5c40\u54e1\u304c\u4ea4\u4ee3\u3067\u6284\u8aad\u4f1a\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002 Rheumatology (Oxford). 2021 May 14;60(5):2348-2354. Acute exacerbation …","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-1707","post","type-post","status-publish","format-standard","hentry","category-reading-session"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1707","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=1707"}],"version-history":[{"count":10,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1707\/revisions"}],"predecessor-version":[{"id":1724,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/1707\/revisions\/1724"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=1707"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=1707"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=1707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}