{"id":2233,"date":"2023-06-30T10:20:14","date_gmt":"2023-06-30T01:20:14","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/cms\/?p=2233"},"modified":"2023-06-30T11:35:06","modified_gmt":"2023-06-30T02:35:06","slug":"%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-67%e3%80%80%e7%9a%ae%e8%86%9a%e7%ad%8b%e7%82%8e1","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-67%e3%80%80%e7%9a%ae%e8%86%9a%e7%ad%8b%e7%82%8e1\/","title":{"rendered":"\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (67)\u3000\u76ae\u819a\u7b4b\u708e(1)\u00a0"},"content":{"rendered":"<p class=\"paragraph\" style=\"margin: 0mm; margin-bottom: .0001pt; text-align: justify; text-justify: inter-ideograph; text-indent: 11.25pt; vertical-align: baseline;\"><span style=\"font-family: verdana, geneva, sans-serif; color: #000080; font-size: 12pt;\"><span class=\"normaltextrun\">\u3055\u3066\u3001\u81e8\u5e8a\u306e\u8a71\u984c\u306b\u623b\u308a\u307e\u3059\u3002\u76ae\u819a\u7b4b\u708e\u306e\u8a71\u3067\u3059\u3002\u76ae\u819a\u7b4b\u708e\u306f\u591a\u767a\u6027\u7b4b\u708e\u3068\u30bb\u30c3\u30c8\u3067\u8b1b\u7fa9\u3067\u3082\u6271\u308f\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u75be\u60a3\u3067\u3059\u304c\u3001\u79c1\u304c\u5b66\u751f\u3084\u7814\u4fee\u533b\u3060\u3063\u305f\u9803\u3068\u306f\u75be\u60a3\u6982\u5ff5\u304c\u5927\u304d\u304f\u5909\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u4ee5\u524d\u306f\u300c\u76ae\u819a\u75c7\u72b6\u306e\u3042\u308b\u591a\u767a\u6027\u7b4b\u708e\u3092\u76ae\u819a\u7b4b\u708e\u3068\u547c\u3076\u300d\u3068\u3044\u3063\u305f\u6271\u3044\u3067\u3057\u305f\u3002\u305d\u308c\u306b\u52a0\u3048\u3066\u3001\u5c11\u3057\u6bdb\u8272\u306e\u7570\u306a\u308b\u300c\u5c01\u5165\u4f53\u7b4b\u708e\u300d\u3068\u3044\u3046\u75be\u60a3\u304c\u3042\u308a\u3001\u3053\u306e\u75be\u60a3\u3082\u6cbb\u7642\u62b5\u6297\u6027\u3067\u306a\u304b\u306a\u304b\u3084\u3063\u304b\u3044\u3067\u3059\u3002<\/span><span class=\"eop\"><span lang=\"EN-US\">\u00a0<\/span><\/span><\/span><\/p>\n<p class=\"paragraph\" style=\"margin: 0mm; margin-bottom: .0001pt; text-align: justify; text-justify: inter-ideograph; text-indent: 11.25pt; vertical-align: baseline;\"><span style=\"font-family: verdana, geneva, sans-serif; color: #000080; font-size: 12pt;\"><span class=\"normaltextrun\">\u3057\u304b\u3057<span lang=\"EN-US\">2003<\/span>\u5e74\u306b\u3001\u65b0\u305f\u306a\u75be\u60a3\u6982\u5ff5\u304c\u63d0\u5531\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u308c\u304c\u514d\u75ab\u4ecb\u5728\u6027\u58ca\u6b7b\u6027\u30df\u30aa\u30d1\u30c1\u30fc<span lang=\"EN-US\">(immune-mediated necrotizing myopathy, IMNM)<\/span>\u3068\u547c\u3070\u308c\u308b\u75be\u60a3\u3067\u3059\u3002\u7b4b\u708e\u3060\u3068\u666e\u901a<span lang=\"EN-US\">myositis<\/span>\u306a\u306e\u3067\u3059\u304c\u3053\u308c\u306f<span lang=\"EN-US\">myopathy<\/span>\uff08\u76f4\u8a33\u3059\u308b\u3068\u7b4b\u75c7\uff09\u3067\u3059\u3002\u3053\u306e\u547c\u3073\u65b9\u306e\u9055\u3044\u306f\u3042\u307e\u308a\u708e\u75c7\u304c\u76ee\u7acb\u305f\u306a\u3044\uff08\u75c5\u7406\u5b66\u7684\u306b\u3001\u514d\u75ab\u62c5\u5f53\u7d30\u80de\u306e\u6d78\u6f64\u304c\u76ee\u7acb\u305f\u306a\u3044\uff09\u3053\u3068\u3092\u610f\u5473\u3059\u308b\u306e\u3060\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u305d\u3046\u306f\u8a00\u3063\u3066\u3082\u6cbb\u7642\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u3068\u514d\u75ab\u6291\u5236\u85ac\u306a\u306e\u3067\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u7bc4\u7587\u306b\u306f\u5165\u308a\u307e\u3059\u3002\u81ea\u5df1\u6297\u4f53\u3082\u6297<span lang=\"EN-US\">HMGCR<\/span>\u6297\u4f53\u3084\u3089\u6297<span lang=\"EN-US\">SRP<\/span>\u6297\u4f53\u306a\u3069\u898b\u3064\u304b\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u81ea\u5df1\u6297\u4f53\u9670\u6027\u4f8b\u3082\u3042\u308a\u307e\u3059\u304c\u300c\u307e\u3060\u898b\u3064\u304b\u3063\u3066\u3044\u306a\u3044\u3060\u3051\u300d\u306e\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/span><span class=\"eop\"><span lang=\"EN-US\">\u00a0<\/span><\/span><\/span><\/p>\n<p class=\"paragraph\" style=\"margin: 0mm; margin-bottom: .0001pt; text-align: justify; text-justify: inter-ideograph; text-indent: 11.25pt; vertical-align: baseline;\"><span style=\"font-family: verdana, geneva, sans-serif; color: #000080; font-size: 12pt;\"><span class=\"normaltextrun\">\u75c5\u7406\u306e\u5148\u751f\u306e\u76ee\u304b\u3089\u306f\u3053\u308c\u307e\u3067\u591a\u767a\u6027\u7b4b\u708e\u3068\u547c\u3070\u308c\u3066\u3044\u305f\u3082\u306e\u306e\u591a\u304f\u306f<span lang=\"EN-US\">IMNM<\/span>\u306b\u5206\u985e\u3055\u308c\u308b\u3088\u3046\u306a\u306e\u3067\u3059\u3002\u3064\u307e\u308a\u591a\u767a\u6027\u7b4b\u708e\u306f\u75c5\u7406\u5b66\u7684\u306b\u306f\u7d76\u6ec5\u5371\u60e7\u7a2e\u3060\u3068\u8a00\u3048\u307e\u3059\u3002<\/span><span class=\"eop\"><span lang=\"EN-US\">\u00a0<\/span><\/span><\/span><\/p>\n<p class=\"paragraph\" style=\"margin: 0mm; margin-bottom: .0001pt; text-align: justify; text-justify: inter-ideograph; text-indent: 11.25pt; vertical-align: baseline;\"><span style=\"font-family: verdana, geneva, sans-serif; color: #000080;\"><span class=\"normaltextrun\" style=\"font-size: 12pt;\">\u305d\u3057\u3066\u3082\u3046\u4e00\u3064\u3001\u79c1\u305f\u3061\u3092\u60a9\u307e\u305b\u3066\u3044\u305f\u75be\u60a3\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u304c\u7121\u7b4b\u75c7\u6027\u76ae\u819a\u7b4b\u708e\u3068\u547c\u3070\u308c\u308b\u4e00\u7fa4\u306e\u75be\u60a3\u3067\u3059\u3002\u4ee5\u524d\u306e\u8003\u3048\u304b\u3089\u8a00\u3046\u3068\u76ae\u819a\u708e\uff0b\u7b4b\u708e\u304c\u76ae\u819a\u7b4b\u708e\u3060\u3063\u305f\u308f\u3051\u3067\u3001\u305d\u3053\u304b\u3089\u7b4b\u75c7\u3092\u5f15\u3051\u3070\u305f\u3060\u306e\u300c\u76ae\u819a\u708e\u300d\u306b\u306a\u308a\u305d\u3046\u306a\u3082\u306e\u3067\u3059\u3002\u91cd\u8981\u306a\u708e\u75c7\u306e\u90e8\u4f4d\u304c\u4e00\u3064\u6b20\u3051\u3066\u3044\u308b\u306e\u3060\u304b\u3089\u8efd\u75c7\u306b\u306a\u308a\u305d\u3046\u306a\u3082\u306e\u3067\u3059\u304c\u3001\u8a71\u306f\u9006\u3067\u3001\u4e0d\u601d\u8b70\u306a\u3053\u3068\u306b\u9593\u8cea\u6027\u80ba\u708e\u5408\u4f75\u4f8b\u304c\u591a\u304f\u3001\u91cd\u75c7\u306b\u306a\u308a\u3084\u3059\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u76ae\u819a\u7b4b\u708e\u306f\u9593\u8cea\u6027\u80ba\u708e\u3092\u5408\u4f75\u3057\u3084\u3059\u3044\u75be\u60a3\u3067\u3059\u304c\u3001\u901a\u5e38\u591a\u3081\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u4f7f\u3046\u3068\u9593\u8cea\u6027\u80ba\u708e\u306e\u9032\u884c\u306f\u6b62\u307e\u308a\u3001\u3086\u3063\u304f\u308a\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u6e1b\u3089\u3057\u3064\u3064\u3001\u4ee3\u308f\u308a\u306b\u514d\u75ab\u6291\u5236\u85ac\u3092\u52a0\u3048\u3066\u3044\u304f\u3053\u3068\u3067\u60a3\u8005\u3055\u3093\u306f\u307b\u307c\u5065\u5e38\u4eba\u3068\u540c\u3058\u751f\u6d3b\u3092\u9001\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u5834\u5408\u3082\u6c7a\u3057\u3066\u73cd\u3057\u304f\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3053\u306e\u7121\u7b4b\u75c7\u6027\u76ae\u819a\u7b4b\u708e\u306e\u5834\u5408\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u5927\u91cf\u306b\u52a0\u3048\u3066\u3082\u9593\u8cea\u6027\u80ba\u708e\u304c\u9032\u884c\u3059\u308b\u3053\u3068\u304c\u591a\u3044\u3068\u3044\u3046\u3084\u3063\u304b\u3044\u306a\u6027\u8cea\u304c\u3042\u308a\u307e\u3059\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u6e1b\u3089\u305b\u306a\u3044\u72b6\u6cc1\u3067\u514d\u75ab\u6291\u5236\u85ac\u3092\u8ffd\u52a0\u305b\u3056\u308b\u3092\u3048\u306a\u304f\u306a\u308a\u3001\u62b5\u6297\u529b\u304c\u843d\u3061\u308b\u305f\u3081\u306b\u901a\u5e38\u306a\u3089\u554f\u984c\u306b\u306a\u3089\u306a\u3044\u3088\u3046\u306a\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u307e\u3067\u611f\u67d3\u75c7\u3092\u8d77\u3053\u3059\uff08\uff1d\u65e5\u548c\u898b\u611f\u67d3\uff09\u3068\u3044\u3046\u3053\u3068\u3067\u6cbb\u7642\u306b\u96e3\u6e0b\u3057\u307e\u3059\u3002\u3053\u306e\u30bf\u30a4\u30d7\u306e\u76ae\u819a\u7b4b\u708e\u306f\u65e5\u672c\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u30a2\u30b8\u30a2\u7cfb\u306e\u4eba\u7a2e\u306b\u591a\u3044\u3088\u3046\u3067\u3001\u8ad6\u6587\u5831\u544a\u3082\u30a2\u30b8\u30a2\u304c\u591a\u3044\u5370\u8c61\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u65e5\u672c\u304b\u3089\u91cd\u8981\u306a\u767a\u898b\u304c\u76f8\u6b21\u304e\u307e\u3057\u305f\u3002\u305d\u308c\u304c\u3053\u306e\u75be\u60a3\u306e\u6cbb\u7642\u306e\u30b9\u30bf\u30a4\u30eb\u3092\u5927\u304d\u304f\u5909\u3048\u3066\u3044\u304f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/span><span class=\"eop\"><span lang=\"EN-US\">\u00a0<\/span><\/span><\/span><\/p>\n<p style=\"text-align: right;\"><strong><span style=\"font-size: 12pt;\">\u4f50\u85e4\u3000\u6d69\u4e8c\u90ce<\/span><\/strong><\/p>\n<p style=\"text-align: right;\"><span style=\"font-size: 11pt;\"><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-66%e3%80%80ai%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6%e6%80%9d%e3%81%86%e3%81%93%e3%81%a82\/\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (66)<\/a><span style=\"color: #0000ff;\"><strong><em>\u2190\u00a0Prev\u3000\u3000\u3000\u3000\u3000Next \u2192<\/em><\/strong><a href=\"https:\/\/www.jichi.ac.jp\/alle\/cms\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-68%e3%80%80%e7%9a%ae%e8%86%9a%e7%ad%8b%e7%82%8e2\/\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (68)<\/a><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"\u3055\u3066\u3001\u81e8\u5e8a\u306e\u8a71\u984c\u306b\u623b\u308a\u307e\u3059\u3002\u76ae\u819a\u7b4b\u708e\u306e\u8a71\u3067\u3059\u3002\u76ae\u819a\u7b4b\u708e\u306f\u591a\u767a\u6027\u7b4b\u708e\u3068\u30bb\u30c3\u30c8\u3067\u8b1b\u7fa9\u3067\u3082\u6271\u308f\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u75be\u60a3\u3067\u3059\u304c\u3001\u79c1\u304c\u5b66\u751f\u3084\u7814\u4fee\u533b\u3060\u3063\u305f\u9803\u3068\u306f\u75be\u60a3\u6982\u5ff5\u304c\u5927\u304d\u304f\u5909\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u4ee5\u524d\u306f\u300c\u76ae\u819a\u75c7\u72b6\u306e\u3042\u308b\u591a\u767a\u6027\u7b4b\u708e\u3092\u76ae\u819a\u7b4b\u708e\u3068\u547c &#8230;","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-2233","post","type-post","status-publish","format-standard","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/2233","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=2233"}],"version-history":[{"count":4,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/2233\/revisions"}],"predecessor-version":[{"id":2243,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/2233\/revisions\/2243"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=2233"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=2233"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=2233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}