{"id":2529,"date":"2025-05-27T16:38:24","date_gmt":"2025-05-27T07:38:24","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/?p=2529"},"modified":"2026-06-16T09:29:14","modified_gmt":"2026-06-16T00:29:14","slug":"%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-95%e3%80%80%e9%96%a2%e7%af%80%e3%83%aa%e3%82%a6%e3%83%9e%e3%83%81%e3%81%a8sle5%e3%80%80%ce%b1%e3%81%8b","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-95%e3%80%80%e9%96%a2%e7%af%80%e3%83%aa%e3%82%a6%e3%83%9e%e3%83%81%e3%81%a8sle5%e3%80%80%ce%b1%e3%81%8b\/","title":{"rendered":"\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (95)\u3000\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3068SLE(5)\u3000\u03b1\u304b\u03b2\u304b\u3001\u305d\u308c\u304c\u554f\u984c\u3060"},"content":{"rendered":"<p>I<span style=\"font-size: 16px; color: #333399;\">FN-\u03b1\u3060\u308d\u3046\u304c\u3001\u03b2\u3060\u308d\u3046\u304c\u3001\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u305f\u5f8c\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u5171\u901a\u306a\u306e\u3060\u304b\u3089\u3069\u3061\u3089\u3067\u3082\u3044\u3044\u3058\u3083\u306a\u3044\u304b\u3001\u3068\u3044\u3046\u8003\u3048\u65b9\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u3046\u3068\u3082\u9650\u308a\u307e\u305b\u3093\u3002\u7523\u751f\u7d30\u80de\u304c\u7570\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002I\u578bIFN\u304c\u03b1\u3001\u03b2\u3068\u540d\u4ed8\u3051\u3089\u308c\u308b\u524d\u306f\u305d\u308c\u305e\u308c\u767d\u8840\u7403IFN, \u7dda\u7dad\u82bd\u7d30\u80deIFN\u3068\u547c\u3070\u308c\u3066\u3044\u305f\u306e\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px; color: #333399;\">\u3000\u305f\u3060\u3057\u79c1\u304c\u535a\u58eb\u8ab2\u7a0b\u3092\u904e\u3054\u3057\u305f\u30e9\u30dc\u3067\u306f\u3001\u300c\u7d30\u80de\u304c\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u306e\u523a\u6fc0\u3092\u53d7\u3051\u308b\u3068\u3001\u307e\u305aIFN-\u03b2\u304c\u7523\u751f\u3055\u308c\u308b\u3002\u305d\u306eIFN-\u03b2\u304c\u305d\u306e\u7d30\u80de\u81ea\u8eab\u3042\u308b\u3044\u306f\u305d\u306e\u5468\u56f2\u306e\u7d30\u80de\u3092\u523a\u6fc0\u3057\uff08\u3064\u307e\u308a\u30aa\u30fc\u30c8\u30af\u30e9\u30a4\u30f3\u3042\u308b\u3044\u306f\u30d1\u30e9\u30af\u30e9\u30a4\u30f3\u7684\u306b\u4f5c\u7528\u3057\u3066\uff09IFN-\u03b1\u306e\u7523\u751f\u3092\u4fc3\u3059\u300d\u3068\u3044\u3046\u4eee\u8aac\u304c\u63d0\u5531\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\uff08\u79c1\u306f\u76f4\u63a5\u305d\u306e\u30c6\u30fc\u30de\u306b\u306f\u95a2\u308f\u3063\u3066\u304a\u3089\u305a\u3001\u7aef\u3067\u898b\u3066\u3044\u305f\u3060\u3051\u306a\u306e\u3067\u8aa4\u89e3\u3057\u3066\u3044\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u30fb\u30fb\u30fb\u3002\uff09\u3053\u306e\u4eee\u8aac\u304c\u6b63\u3057\u3051\u308c\u3070\u3001\u3069\u306e\u307f\u3061\u6700\u7d42\u7684\u306b\u7523\u751f\u3055\u308c\u308b\u306e\u306fIFN-\u03b1\u3067\u3042\u308b\u3001\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057Sakashita et al.\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u3066\u3044\u305f\u306e\u306fIFN-\u03b2\u306e\u65b9\u3067\u3059\u3002\u3064\u307e\u308aIFN-\u03b2\u304c\u4e3b\u306b\u7523\u751f\u3055\u308cIFN-\u03b1\u306f\u8a98\u5c0e\u3055\u308c\u306a\u3044\u3001\u3068\u3044\u3046\u72b6\u6cc1\u304c\u3042\u308a\u5f97\u308b\u3068\u3044\u3046\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px; color: #333399;\">\u3000\u5b9f\u306f\u79c1\u3082\u60a3\u8005\u7531\u6765\u8840\u6e05\u3067I\u578bIFN\u3092\u6e2c\u5b9a\u3057\u3066\u3044\u308b\u6642\u306b\u76ae\u819a\u7b4b\u708e\u3084SLE\u60a3\u8005\u3067\u306fIFN-\u03b1\u304c\u4e3b\u306b\u691c\u51fa\u3055\u308c\u308b\u304c\u3001\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3067\u306fIFN-\u03b2\u304c\u4e3b\u306b\u691c\u51fa\u3055\u308c\u308b\u3001\u3068\u3044\u3046\u3053\u3068\u306b\u6c17\u3065\u3044\u3066\u3044\u307e\u3057\u305f\u3002\u3064\u307e\u308aSakashita et al. \u3068\u540c\u3058\u3067\u3059\u3002\u307e\u3042\u4e00\u81f4\u3059\u308b\u3053\u3068\u81ea\u4f53\u306f\u305d\u308c\u307b\u3069\u9a5a\u304f\u3079\u304d\u7d50\u679c\u3067\u306f\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3068\u3044\u3046\u306e\u3082\u540c\u3058\u4f1a\u793e\u306e\u540c\u3058\u6a5f\u5668\u30fb\u8a66\u85ac\u3092\u4f7f\u3063\u3066\u6e2c\u5b9a\u3057\u3066\u3044\u305f\u304b\u3089\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px; color: #333399;\">\u3000\u96e3\u3057\u3044\u70b9\u306f\u3001IFN-\u03b1\u306b\u3057\u308d\u03b2\u306b\u3057\u308d\u3001\u691c\u51fa\u9650\u754c\u306e\u30ae\u30ea\u30ae\u30ea\u306e\u6fc3\u5ea6\u3060\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u6e2c\u5b9a\u3067\u304d\u306a\u3044\u60a3\u8005\u3082\u591a\u3044\u306e\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u4f4e\u3044\u6fc3\u5ea6\u3068\u3044\u3046\u3053\u3068\u306f\u8aa4\u5dee\u306e\u5272\u5408\u3082\u5927\u304d\u3044\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u7d50\u679c\u306e\u89e3\u91c8\u306b\u306f\u614e\u91cd\u3055\u304c\u5fc5\u8981\u3067\u3059\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px; color: #333399;\">\u3000\u3057\u304b\u3057\u6614\u306e\u7814\u7a76\u8005\u304c\u8003\u3048\u305f\u3088\u3046\u306bIFN-\u03b1\u304c\u767d\u8840\u7403\uff08\u3053\u306e\u4e2d\u306b\u306f\u5f53\u7136\u5f62\u8cea\u7d30\u80de\u69d8\u6a39\u72b6\u7d30\u80de\uff50DC\u3082\u542b\u307e\u308c\u308b\u3067\u3057\u3087\u3046\uff09\u3001IFN-\u03b2\u304c\u7dda\u7dad\u82bd\u7d30\u80de\u304b\u3089\u4e3b\u306b\u7523\u751f\u3055\u308c\u308b\u306e\u306a\u3089\u3001\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u5834\u5408\u306f\u6ed1\u819c\u7dda\u7dad\u82bd\u7d30\u80de\u304b\u3089\u51fa\u3066\u3044\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u5b9f\u969b\u3001\u6614\u304b\u3089\u30a6\u30a4\u30eb\u30b9\u306e\u523a\u6fc0\u3092\u6a21\u5023\u3059\u308b\u523a\u6fc0\u3068\u3057\u3066\u4f7f\u308f\u308c\u3066\u304d\u305fpoly I-C\uff08\u4e8c\u672c\u9396RNA\uff09\u3092\u6ed1\u819c\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u3075\u308a\u304b\u3051\u308b\u3068\u3001\u57f9\u990a\u4e0a\u6e05\u4e2d\u306bIFN-\u03b2\u304c\u4e3b\u306b\u7523\u751f\u3055\u308c\u3001IFN-\u03b1\u306f\u307b\u3068\u3093\u3069\u691c\u51fa\u3067\u304d\u307e\u305b\u3093\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u672b\u68a2\u8840\u7531\u6765\u5358\u6838\u7403\u306bpoly I-C\u3092\u52a0\u3048\u305f\u5834\u5408\u3001\u3069\u3061\u3089\u306eIFN\u3082\u7523\u751f\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/span><\/p>\n<p style=\"text-align: right;\"><span style=\"font-size: 16px;\"><strong>\u4f50\u85e4\u3000\u6d69\u4e8c\u90ce<\/strong><\/span><\/p>\n<p style=\"text-align: right;\"><span style=\"color: #000080; font-size: 14px;\"><a style=\"color: #000080;\" href=\"https:\/\/www.jichi.ac.jp\/alle\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-94%e3%80%80%e9%96%a2%e7%af%80%e3%83%aa%e3%82%a6%e3%83%9e%e3%83%81%e3%81%a8sle4%e3%80%80%e9%96%a2%e7%af%80\/\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081 (94)<\/a><em><strong>\u2190<span style=\"color: #0000ff;\"> Prev\u3000\u3000\u3000\u3000\u3000Next<\/span>\u2192<\/strong><\/em><a style=\"color: #000080;\" href=\"https:\/\/www.jichi.ac.jp\/alle\/%e6%95%99%e6%8e%88%e3%81%b6%e3%82%8d%e3%81%90%ef%bc%88%e8%b6%85%e4%b8%8d%e5%ae%9a%e6%9c%9f%e6%8e%b2%e8%bc%89%ef%bc%89\/%e7%a7%81%e7%9a%84%e5%85%8d%e7%96%ab%e5%ad%a6%e3%81%93%e3%81%a8%e3%81%af%e3%81%98%e3%82%81-96%e3%80%80%e9%96%a2%e7%af%80%e3%83%aa%e3%82%a6%e3%83%9e%e3%83%81%e3%81%a8sle6%e3%80%80i%e5%9e%8bifn\/\">\u79c1\u7684\u514d\u75ab\u5b66\u3053\u3068\u306f\u3058\u3081(96)<\/a>\u3000<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"IFN-\u03b1\u3060\u308d\u3046\u304c\u3001\u03b2\u3060\u308d\u3046\u304c\u3001\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u305f\u5f8c\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u5171\u901a\u306a\u306e\u3060\u304b\u3089\u3069\u3061\u3089\u3067\u3082\u3044\u3044\u3058\u3083\u306a\u3044\u304b\u3001\u3068\u3044\u3046\u8003\u3048\u65b9\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u3046\u3068\u3082\u9650\u308a\u307e\u305b\u3093\u3002\u7523\u751f\u7d30\u80de\u304c\u7570\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002I\u578bIFN\u304c\u03b1\u3001\u03b2\u3068\u540d\u4ed8\u3051\u3089\u308c\u308b\u524d\u306f\u305d &#8230;","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-2529","post","type-post","status-publish","format-standard","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/2529","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=2529"}],"version-history":[{"count":4,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/2529\/revisions"}],"predecessor-version":[{"id":2608,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/2529\/revisions\/2608"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=2529"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=2529"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=2529"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}