{"id":685,"date":"2020-01-30T09:18:20","date_gmt":"2020-01-30T00:18:20","guid":{"rendered":"https:\/\/www.jichi.ac.jp\/alle\/cms\/?p=685"},"modified":"2020-01-30T09:18:20","modified_gmt":"2020-01-30T00:18:20","slug":"685","status":"publish","type":"post","link":"https:\/\/www.jichi.ac.jp\/alle\/reading-session\/685\/","title":{"rendered":"\u6284\u8aad\u4f1a\u30002020\u5e741\u670830\u65e5"},"content":{"rendered":"<p>\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u5b66\u3067\u306f\u6bce\u9031\u533b\u5c40\u54e1\u304c\u4ea4\u4ee3\u3067\u6284\u8aad\u4f1a\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n<p><span style=\"color: #000080;\">N Engl J Med. 2020 Jan 16;382(3):211-221.<\/span><br \/>\n<span style=\"color: #000080;\">Trial of Anifrolumab in Active Systemic Lupus Erythematosus.<\/span><\/p>\n<p><span style=\"color: #000080;\">SLE\u306e\u60a3\u8005\u3055\u3093\u306banifrolumab 300 mg (\u6297type I IFN\u53d7\u5bb9\u4f53\u30b5\u30d6\u30e6\u30cb\u30c3\u30c81\u306b\u5bfe\u3059\u308b<br \/>\n<\/span><span style=\"color: #000080;\">\u6297\u4f53\uff09\u3068<\/span><span style=\"color: #000080;\">\u30d7\u30e9\u30bb\u30dc\u30924\u9031\u3054\u3068\u306b1\u5e74\u9593\u6295\u4e0e\u3057\u305f\u8a66\u9a13\u3002\u30d7\u30e9\u30a4\u30de\u30ea\u30fc\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f<br \/>\nBICLA response\u3092<\/span><span style=\"color: #000080;\">\u9054\u6210\u3067\u304d\u305f\u5272\u5408\u3068\u3057\u305f\u3002<br \/>\nBICLA response \u306fanifrolumab\u7fa4 47.8%\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u300031.5%\u3068\u3001<\/span><span style=\"color: #000080;\">\u30d7\u30e9\u30bb\u30dc\u7fa4\u3068<br \/>\n\u6bd4\u8f03\u3057\u6709\u610f\u306b\u6539\u5584\u304c\u307f\u3089\u308c\u305f\uff08\u5dee\u300016.3%\u3001P=0.001)\u3002<br \/>\n<\/span><span style=\"color: #000080;\">\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u3001\u76ae\u819a\u75c7\u72b6\u306e\u6539\u5584\u3082anifrolumab\u7fa4\u3067\u6709\u610f\u3060\u3063\u305f\u304c\u3001\u95a2\u7bc0\u75c7\u72b6\u306e\u6539\u5584\u3068<br \/>\n\u5e74\u63db<\/span><span style=\"color: #000080;\">\u7b97\u518d\u767a\u7387\u306b\u306f\u6709\u610f\u5dee\u304c\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u3002<br \/>\n<\/span><span style=\"color: #000080;\">anifrolumab\u7fa4\u3067\u306f\u5e2f\u72b6\u75b1\u75b9\u304c7.2%\u3001\u6c17\u7ba1\u652f\u708e\u304c12.2%\u306b\u898b\u3089\u308c\u305f\u3002<\/span><br \/>\n<span style=\"color: #000080;\">anifrolumab\u306f\u3001\u305d\u308c\u307b\u3069\u5287\u7684\u306b\u52b9\u304f\u85ac\u3067\u306f\u306a\u3055\u305d\u3046\u3067\u3059\u2026\u3002<\/span><\/p>\n<p style=\"text-align: right;\"><span style=\"color: #000080;\">\u62c5\u5f53\u3000N<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u5b66\u3067\u306f\u6bce\u9031\u533b\u5c40\u54e1\u304c\u4ea4\u4ee3\u3067\u6284\u8aad\u4f1a\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002 N Engl J Med. 2020 Jan 16;382(3):211-221. Trial of Anifrolumab in Activ &#8230;","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-685","post","type-post","status-publish","format-standard","hentry","category-reading-session"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/685","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/comments?post=685"}],"version-history":[{"count":0,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/posts\/685\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/media?parent=685"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/categories?post=685"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/alle\/wp-json\/wp\/v2\/tags?post=685"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}