自治医科大学 炎症・免疫研究部
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自治医大HPに戻る

2024
1. Usui-Kawanishi F, Kani K, Karasawa T, Honda H, Takayama N, Takahashi M, Takatsu K, Nagai Y. Isoliquiritigenin inhibits NLRP3 inflammasome activation with CAPS mutations by suppressing caspase-1 activation and mutated NLRP3 aggregation. Genes Cells (in press)

2. Tanaka H, Ozawa R, Henmi Y, Hosoda M, Karasawa T, Takahashi M, Takahashi H, Iwata H, Kuwayama T, Shirasuna K. Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages. Reprod Biol (in press)

2023
1. Karasawa T, Komada T, Baatarjav C, Aizawa E, Mizushina Y, Fujimura K, Gunji Y, Komori S, Aizawa H, Jing Tao BK Matsumura T, Takahashi M. Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice. Biochem Biophys Res Commun 686: 149158, 2023

2. Kadoya H, Hirano A, Umeno R, Kajimoto E, Iwakura T, Kondo M, Wada Y, Kidokoro K, Kishi S, Nagasu H, Sasaki T, Taniguchi S, Takahashi M, Kashihara N. Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis. FASEB J 37: e23129, 2023

3. Fujimura K, Karasawa T, Komada T, Yamada N, Mizushina Y, Baatarjav C, Matsumura T, Otsu K, Takeda N, Mizukami H, Kario K, Takahashi M. NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy. J Mol Cell Cardiol 180: 58-68, 2023

2022
1. Matsumura T, Totani H, Gunji Y, Fukuda M, Yokomori R, Deng J, Rethnam M, Yang C, Tan TK, Karasawa T, Kario K, Takahashi M, Osato M, Sanda T, Suda T. A Myb enhancer-guided analysis of basophil and mast cell differentiation. Nat Commun 13: 7064, 2022


2. Baatarjav C, Komada T, Karasawa T, Yamada N, Sampilvanjil A, Matsumura T, Takahashi M. dsDNA-induced AIM2 pyroptosis halts aberrant inflammation during rhabdomyolysis-induced acute kidney injury. Cell Death Differ 29: 2487-2502, 2022

3. Karasawa T, Komada T, Yamada N, Aizawa E, Mizushina Y, Watanabe S, Baatarjav C, Matsumura T, Takahashi M. Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome. eLife 11:e75166, 2022

4. Takahashi M. NLRP3 inflammasome as a key driver of vascular disease. Cardiovasc Res 118: 372-385, 2022

5. Abishai Dominic, Nhat-Tu Le, Takahashi M. Loop between NLRP3 inflammasome and reactive oxygen species. Antioxid Redox Signal 36: 784-796, 2022

6. Ozeki A, Oogaki Y, Henmi Y, Karasawa T, Takahashi M, Takahashi H, Ohkuchi A, Shirasuna K. Elevated S100A9 in preeclampsia induces soluble endoglin and IL-1β secretion and hypertension via the NLRP3 inflammasome. J Hypertens 40: 84-93, 2022

7. Sano M, Komiyama H, Shinoda R, Ozawa R, Watanabe H, Karasawa T, Takahashi M, Torii Y, Iwata H, Kuwayama T, Shirasuna K. NLRP3 inflammasome is involved in testicular inflammation induced by lipopolysaccharide in mice. Am J Reprod Immunol e13527, 2022