{"id":19,"date":"2023-08-31T11:13:24","date_gmt":"2023-08-31T02:13:24","guid":{"rendered":"https:\/\/jmu-cgtr.jp\/?page_id=19"},"modified":"2026-08-05T18:22:15","modified_gmt":"2026-08-05T09:22:15","slug":"achievement","status":"publish","type":"page","link":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/achievement\/","title":{"rendered":"\u7814\u7a76\u6d3b\u52d5"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">\u7814\u7a76\u7d39\u4ecb<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e<strong>\u8102\u8cea\u30ca\u30ce\u7c92\u5b50\u3092\u7528\u3044\u305f\u5869\u57fa\u7de8\u96c6\u306b\u3088\u308a\u8840\u53cb\u75c5B\u306e\u539f\u56e0\u907a\u4f1d\u5b50\u5909\u7570\u3092\u30de\u30a6\u30b9\u3067\u4fee\u5fa9<\/strong><br><strong>\u2015 \u907a\u4f1d\u5b50\u88dc\u5145\u7642\u6cd5\u306b\u4ee3\u308f\u308b\u65b0\u305f\u306a\u6839\u6cbb\u7684\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642\u306e\u53ef\u80fd\u6027 \u2015<\/strong><\/p>\n\n\n\n<p 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href=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2026\/08\/597bb57210617e3d7d3b6fbe2b124303.pdf\">https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2026\/08\/597bb57210617e3d7d3b6fbe2b124303.pdf<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e<strong>\u30e2\u30f3\u30b4\u30eb\u3067\u306f\u591a\u304f\u306e\u8840\u53cb\u75c5\u60a3\u8005\u304cAAV\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u59a8\u3052\u308bAAV\u4e2d\u548c\u6297\u4f53\u3092\u4fdd\u6709<\/strong><br>\u2015\u5730\u57df\u3054\u3068\u306e\u514d\u75ab\u5b66\u7684\u80cc\u666f\u304b\u3089\u6b21\u4e16\u4ee3\u6cbb\u7642\u958b\u767a\u306e\u5fc5\u8981\u6027\u3082\u793a\u5506\u2015<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u751f\u5316\u5b66\u90e8\u9580\u75c5\u614b\u751f\u5316\u5b66\u90e8\u9580\u3001\u304a\u3088\u3073\u30e2\u30f3\u30b4\u30eb\u56fd\u7acb\u533b\u79d1\u5927\u5b66\u306e\u56fd\u969b\u5171\u540c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u3067\u5e83\u304f\u7528\u3044\u3089\u308c\u308b\u30a2\u30c7\u30ce\u968f\u4f34\u30a6\u30a4\u30eb\u30b9\uff08AAV\uff09\u306b\u5bfe\u3059\u308b\u4e2d\u548c\u6297\u4f53\u306e\u4fdd\u6709\u72b6\u6cc1\u3092\u30e2\u30f3\u30b4\u30eb\u3067\u521d\u3081\u3066\u8a73\u7d30\u306b\u89e3\u6790\u3057\u3001\u6297AAV\u4e2d\u548c\u6297\u4f53\u306e\u4fdd\u6709\u7387\u304c\u9ad8\u3044\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<br>\u8a73\u7d30\u306f\u3053\u3061\u3089\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<a href=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2026\/08\/66999d3d382b3be15462b8e9eb1dd84e.pdf\">https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2026\/08\/66999d3d382b3be15462b8e9eb1dd84e.pdf<\/a><br><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e\u300cNHK World Japan\u300d\u3067\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u5c0f\u5150\u79d1\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u53d6\u308a\u7d44\u307f\u306b\u3064\u3044\u3066\u53d6\u308a\u4e0a\u3052\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002 \u5c11\u3057\u3067\u3059\u304c\u3001\u5148\u65e5\u958b\u50ac\u3044\u305f\u3057\u307e\u3057\u305f\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7\u306e\u69d8\u5b50\u3082\u3054\u3056\u3044\u307e\u3059\u3002 \uff082025.12.4\uff09<br>\u4e0b\u8a18\u30ea\u30f3\u30af\u5148\u304b\u3089\u52d5\u753b\u7b49\u3092\u3054\u8996\u8074\u304f\u3060\u3055\u3044\u3002<br>Podcast  <a href=\"https:\/\/t.co\/ymBAaMwRTR\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/podcasts.apple.com\/jp\/podcast\/english-news-nhk-world-radio-japan\/id141016660?i=1000739573278<\/a> <br>NHK  <a href=\"https:\/\/t.co\/AU3sPQklpw\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www3.nhk.or.jp\/nhkworld\/en\/news\/videos\/20251203213328537\/index.html<\/a> <br>YouTube  <a href=\"https:\/\/t.co\/0MHyMy8Qix\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/youtu.be\/unC8s8AnyjQ<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e<strong>Baatartsogt\u52a9\u6559\u306e\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u3092\u7528\u3044\u305f\u7b2cIX\u56e0\u5b50\u3078\u306e\u6a5f\u80fd\u7372\u5f97\u578b\u5909\u7570\u8a98\u5c0e\u306b\u3088\u308b\u8840\u53cb\u75c5B\u6cbb\u7642\u6280\u8853\u304c\u7c73\u56fd\u8840\u6db2\u5b66\u4f1a\u8a8cBlood\u306b\u53d7\u7406\u3055\u308c\u307e\u3057\u305f\u3002<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e<strong>\u56fd\u7523\u8840\u53cb\u75c5A\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u4e00\u6b69\u524d\u3078 \u2212\u6a5f\u80fd\u3092\u5f37\u5316\u3057\u305f\u6539\u5909\u578b\u7b2cVIII\u56e0\u5b50\u306e\u958b\u767a\u2212<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u751f\u5316\u5b66\u8b1b\u5ea7\u75c5\u614b\u751f\u5316\u5b66\u90e8\u9580\u3001\u5948\u826f\u770c\u7acb\u533b\u79d1\u5927\u5b66\u3001\u6771\u4eac\u5927\u5b66\u3001Nezu Life Sciences\u3001\u5927\u962a\u5927\u5b66\u3001\u4e88\u9632\u885b\u751f\u5354\u4f1a\u306e\u5171\u540c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30d2\u30c8\u8840\u6db2\u51dd\u56fa\u7b2cVIII\u56e0\u5b50\uff08FVIII\uff09\u306e\u51dd\u56fa\u6d3b\u6027\u304a\u3088\u3073\u5206\u6ccc\u52b9\u7387\u3092\u5927\u5e45\u306b\u5411\u4e0a\u3055\u305b\u305f\u65b0\u898f\u6539\u5909\u578bFVIII\u306e\u958b\u767a\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u8840\u53cb\u75c5A\u306b\u5bfe\u3059\u308b\u4f4e\u7528\u91cfAAV\u30d9\u30af\u30bf\u30fc\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u5b9f\u73fe\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u9577\u671f\u7684\u306a\u6cbb\u7642\u52b9\u679c\u3068\u5b89\u5168\u6027\u306e\u4e21\u7acb\u3092\u53ef\u80fd\u306b\u3059\u308b\u65b0\u305f\u306a\u6280\u8853\u57fa\u76e4\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u672c\u6280\u8853\u306b\u3088\u308a\u3001\u56fd\u7523\u306e\u8840\u53cb\u75c5A\u907a\u4f1d\u5b50\u6cbb\u7642\u85ac\u306e\u5b9f\u7528\u5316\u304c\u5927\u304d\u304f\u524d\u9032\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<br>\u672c\u7814\u7a76\u5185\u5bb9\u306f\u3001\u7c73\u56fd\u8840\u6db2\u5b66\u4f1a\u8a8c Blood\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<br>\u8ad6\u6587\u540d\uff1aEngineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy<br>\u63b2\u8f09\u8a8c\uff1aBlood<br>DOI:&nbsp;<a href=\"https:\/\/doi.org\/10.1182\/blood.2025028481\">https:\/\/doi.org\/10.1182\/blood.2025028481<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a73\u7d30\u306f\u3053\u3061\u3089\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<br><a href=\"https:\/\/www.jichi.ac.jp\/wp\/wp-content\/uploads\/2025\/11\/20251107.pdf\">https:\/\/www.jichi.ac.jp\/wp\/wp-content\/uploads\/2025\/11\/20251107.pdf<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e<strong>\u907a\u4f1d\u5b50\u3092\u201c\u4fee\u5fa9\u201d\u304b\u3089\u201c\u5f37\u5316\u201d\u3078 \u3000\uff5e\u5869\u57fa\u7de8\u96c6\u6280\u8853\u3092\u7528\u3044\u305f\u8840\u53cb\u75c5B\u306b\u5bfe\u3059\u308b\u65b0\u3057\u3044\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642\uff5e<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u751f\u5316\u5b66\u8b1b\u5ea7\u75c5\u614b\u751f\u5316\u5b66\u90e8\u9580\u3001\u5317\u6d77\u9053\u5927\u5b66\u3001\u5fb3\u5cf6\u5927\u5b66\u3001\u4eac\u90fd\u5e9c\u7acb\u533b\u79d1\u5927\u5b66\u3001\u6771\u4eac\u5927\u5b66\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30d2\u30c8\u8840\u6db2\u51dd\u56fa\u7b2cIX\u56e0\u5b50\u907a\u4f1d\u5b50\u306b\u6a5f\u80fd\u7372\u5f97\u578b\u5909\u7570\u3092\u5c0e\u5165\u3059\u308b\u5869\u57fa\u7de8\u96c6\u6280\u8853\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u306f\u3001\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u907a\u4f1d\u5b50\u5909\u5316\u3092\u300c\u5143\u306b\u623b\u3059\u300d\u5f93\u6765\u306e\u907a\u4f1d\u5b50\u4fee\u5fa9\u578b\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u8d85\u3048\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3092\u610f\u56f3\u7684\u306b\u5f37\u5316\u3059\u308b\u201c\u6a5f\u80fd\u7372\u5f97\u578b\u201d\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642\u3068\u3044\u3046\u65b0\u3057\u3044\u6cbb\u7642\u30d1\u30e9\u30c0\u30a4\u30e0\u3092\u63d0\u793a\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u3053\u306e\u6226\u7565\u306f\u3001\u8840\u53cb\u75c5B\u306e\u307f\u306a\u3089\u305a\u3001\u4ed6\u306e\u907a\u4f1d\u6027\u75be\u60a3\u306b\u3082\u5fdc\u7528\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<br>\u672c\u7814\u7a76\u5185\u5bb9\u306f\u3001\u7c73\u56fd\u8840\u6db2\u5b66\u4f1a\u8a8c\u3000Blood\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<br>\u8ad6\u6587\u540d\uff1aTherapeutic base editing to generate a gain-of-function F9 variant for hemophilia B<br>\u63b2\u8f09\u8a8c\uff1aBlood<br>DOI:&nbsp;<a href=\"https:\/\/doi.org\/10.1182\/blood.2024027870\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1182\/blood.2024027870<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><img decoding=\"async\" class=\"wp-image-1311\" style=\"width: NaNpx;\" src=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2025\/11\/20251029_R338Q.pdf\" alt=\"\">\u8a73\u7d30\u306f\u3053\u3061\u3089\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002\u3000<br><a href=\"https:\/\/www.jichi.ac.jp\/wp\/wp-content\/uploads\/2025\/10\/20251029_R338Q.pdf\">https:\/\/www.jichi.ac.jp\/wp\/wp-content\/uploads\/2025\/10\/20251029_R338Q.pdf<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#x25fc;\ufe0e\u51a8\u6a2b\u670b\u8cb4\u3055\u3093\u3089\u306e\u7814\u7a76\u8ad6\u6587\u304c\u3001&nbsp;\u7c73\u56fd\u5fc3\u81d3\u5354\u4f1a\u306e\u56fd\u969b\u533b\u5b66\u96d1\u8a8c\u300e<em><strong>Arteriosclerosis, Thrombosis, and Vascular Biology<\/strong><\/em>\u300f\u306b\u304a\u3044\u3066\u3001&nbsp;2024\u5e74\u306b\u63b2\u8f09\u3055\u308c\u305f400\u7bc7\u306e\u8ad6\u6587\u306e\u4e2d\u304b\u3089\u8840\u6813\u75c7\u5206\u91ce\u3067\u6700\u3082\u512a\u308c\u305f\u8ad6\u6587\u306b\u9078\u51fa\u3055\u308c\u3001&nbsp;Karl Link Early Career Investigator Award\u3092\u53d7\u8cde\u3057\u3001\u30dc\u30eb\u30c1\u30e2\u30a2\u3067\u884c\u308f\u308c\u305fVascular Discovery 2025\u3067\u53d7\u8cde\u8b1b\u6f14\u3068\u6388\u8cde\u5f0f\u304c\u57f7\u308a\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/ATVBAHA.125.322551\">https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/ATVBAHA.125.322551<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<div class=\"wp-block-group tile__list\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full tile__img\"><a href=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/page-490\/\"><img decoding=\"async\" width=\"1372\" height=\"772\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2023\/11\/achievement_1-jpg.webp\" alt=\"\" class=\"wp-image-393\" style=\"object-fit:cover\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2023\/11\/achievement_1-jpg.webp 1372w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2023\/11\/achievement_1-300x169.webp 300w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2023\/11\/achievement_1-1024x576.webp 1024w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2023\/11\/achievement_1-768x432.webp 768w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2023\/11\/achievement_1-670x377.webp 670w\" sizes=\"(max-width: 1372px) 100vw, 1372px\" \/><\/a><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\">\u4e2d\u6838\u62e0\u70b9\u4e8b\u696d<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full tile__img is-style-default\"><a href=\"https:\/\/jichi-biochem.jp\/\"><img decoding=\"async\" width=\"329\" height=\"263\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2024\/08\/15769811f422196c9a882f404d1fba95-2.png\" alt=\"\" class=\"wp-image-886\" style=\"aspect-ratio:4\/3;object-fit:contain\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/15769811f422196c9a882f404d1fba95-2.png 329w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/15769811f422196c9a882f404d1fba95-2-300x240.png 300w\" sizes=\"(max-width: 329px) 100vw, 329px\" \/><\/a><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\">\u75c5\u614b\u751f\u5316\u5b66\u90e8\u9580<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-medium tile__img\"><a href=\"https:\/\/www.jichi.ac.jp\/hospital\/top\/jcmct\/department\/\"><img decoding=\"async\" width=\"300\" height=\"84\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2024\/08\/9c7606383a88e90678da4f86989d4dea-300x84.png\" alt=\"\" class=\"wp-image-894\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/9c7606383a88e90678da4f86989d4dea-300x84.png 300w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/9c7606383a88e90678da4f86989d4dea.png 587w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\">\u5c0f\u5150\u79d1\u5b66<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full tile__img\"><img decoding=\"async\" width=\"475\" height=\"463\" src=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/51cd154088b7ed96773c45487e9c889b.png\" alt=\"\" class=\"wp-image-931\" style=\"object-fit:cover\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/51cd154088b7ed96773c45487e9c889b.png 475w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/51cd154088b7ed96773c45487e9c889b-300x292.png 300w\" sizes=\"(max-width: 475px) 100vw, 475px\" \/><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\"><a href=\"https:\/\/www.jichi.ac.jp\/kinou\/\">\u6a5f\u80fd\u751f\u5316\u5b66\u90e8\u9580<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full tile__img\"><a href=\"https:\/\/www.jichi.ac.jp\/medicine\/department\/aav\/\"><img decoding=\"async\" width=\"475\" height=\"463\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2024\/08\/51cd154088b7ed96773c45487e9c889b.png\" alt=\"\" class=\"wp-image-931\" style=\"object-fit:cover\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/51cd154088b7ed96773c45487e9c889b.png 475w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/51cd154088b7ed96773c45487e9c889b-300x292.png 300w\" sizes=\"(max-width: 475px) 100vw, 475px\" \/><\/a><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\"><a href=\"https:\/\/www.jichi.ac.jp\/medicine\/department\/aav\/\">\u795e\u7d4c\u907a\u4f1d\u5b50\u6cbb\u7642\u90e8\u9580<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full is-resized tile__img\"><a href=\"https:\/\/www.jichi.ac.jp\/saisei\/\"><img decoding=\"async\" width=\"1000\" height=\"284\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2024\/08\/header.png\" alt=\"\" class=\"wp-image-922\" style=\"object-fit:cover;width:246px;height:auto\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/header.png 1000w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/header-300x85.png 300w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/header-768x218.png 768w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/header-670x190.png 670w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/a><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\"><a href=\"https:\/\/www.jichi.ac.jp\/saisei\/\">\u518d\u751f\u533b\u5b66\u7814\u7a76\u90e8<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\"><div class=\"wp-block-image tile__img\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/www.jichi.ac.jp\/genetherapy\/\"><img decoding=\"async\" width=\"960\" height=\"510\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2024\/08\/img20231222143457809818.webp\" alt=\"\" class=\"wp-image-920\" style=\"object-fit:cover\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/img20231222143457809818.webp 960w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/img20231222143457809818-300x159.webp 300w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/img20231222143457809818-768x408.webp 768w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/img20231222143457809818-670x356.webp 670w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p class=\"tile__ttl wp-block-paragraph\"><a href=\"https:\/\/www.jichi.ac.jp\/genetherapy\/\">\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u90e8<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full tile__img\"><a href=\"https:\/\/www.jichi.ac.jp\/usr\/hema\/index.html\"><img decoding=\"async\" width=\"360\" height=\"240\" data-id=\"928\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2024\/08\/medical_services_12_img01.jpg\" alt=\"\" class=\"wp-image-928\" srcset=\"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/medical_services_12_img01.jpg 360w, https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-content\/uploads\/2024\/08\/medical_services_12_img01-300x200.jpg 300w\" sizes=\"(max-width: 360px) 100vw, 360px\" \/><\/a><\/figure>\n<\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\"><a href=\"https:\/\/www.jichi.ac.jp\/usr\/hema\/index.html\">\u8840\u6db2\u5b66\u90e8\u9580<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group tile__item\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image size-full tile__img\"><img decoding=\"async\" width=\"300\" height=\"225\" src=\"https:\/\/jmu-cgtr.jp\/wp-content\/uploads\/2023\/12\/no-img-jpg-e1702963661851.webp\" alt=\"\" class=\"wp-image-506\" style=\"object-fit:cover\"\/><\/figure>\n\n\n\n<p class=\"tile__ttl wp-block-paragraph\"><\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u696d\u7e3e<\/h3>\n\n\n\n<div class=\"wp-block-group accordion\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group accordion_ttl\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading\">2024\u5e74<\/h4>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion_wrap\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h5 class=\"wp-block-heading\">A. \u539f\u8457\u8ad6\u6587<\/h5>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<ol class=\"wp-block-list\">\n<li>Abdou, K., Nomoto, M., Aly, MH., Ibrahim, AZ., Choko, K., Okubo-Suzuki, R., Muramatsu, S., Inokuchi, K.: Prefrontal coding of learned and inferred knowledge during REM and NREM sleep. Nat Commun 15(1):4566, 2024.<\/li>\n\n\n\n<li>Abe, T., Endo, K., Hanazono, Y., Kobayashi, E.: In Vivo Luciferin-Luciferase Reaction in Micro-Mini Pigs Using Xenogeneic Rat Bone Marrow Transplantation Int J Mol Sci. 2024 Aug 7;25(16):8609. doi: 10.3390\/ijms25168609.<\/li>\n\n\n\n<li>Baatartsogt, N., Kashiwakura, Y., Hiramoto,T., Ito, R., Sato, R., Nagao, Y., Hina Naruoka, H., Takata, H., Hayakawa, M., Batjargal, K., Togashi,&nbsp; T., Hoshino, A., Shimizu, T., Sato, Y., Ishida, T., Nureki, O., Ohmori, T.: Universal base editing for hemophilia B. bioRxiv 2024.11.13.623331; doi:https:\/\/doi.org\/10.1101\/2024.11.13.623331.<\/li>\n\n\n\n<li>Hayashi, Y., Sehara, Y., Watano, R., Ohba, K., Takayanagi, Y., Sakiyama, Y., Muramatsu, K., Mizukami, H.: Therapeutic Strategy for Fabry Disease by Intravenous Administration of Adeno-Associated Virus 9 in a Symptomatic Mouse Model. Hum Gene Ther 35(5-6): 192-201, 2024.<\/li>\n\n\n\n<li>Hidema, S., Sato, K., Mizukami, H., Takahashi, Y., Maejima, Y., Shimomura, K., Nishimori, K.: Oxytocin receptor-expressing neurons in the medial preoptic area are essential for lactation, whereas those in the lateral septum are not critical for maternal behavior. Neuroendocrinol 114: 517-37, 2024.<\/li>\n\n\n\n<li>Hino, T., Nakahara, F., Miyauchi, M., Ito, Y., Masamoto, Y., Morita, K., Kagoya, Y., Kojima, H., Kurokawa, M.: AKT2 inhibition accelerates the acquisition of phagocytic ability in induced pluripotent stem cell-derived neutrophils. Exp Hematol. 2024 Feb;130:104137. doi: 10.1016\/j.exphem.2023.104137.<\/li>\n\n\n\n<li>Izuo, N., Ikejima, D., Uno, K., Asano, T., Muramatsu, S., Nitta, A.:Hippocampus-specific knockdown of Shati\/Nat8l impairs cognitive function and electrophysiological response in mice. Biochem Biophys Res Commun 736:150435, 2024.<\/li>\n\n\n\n<li>Kaneko, Y., Ohzawa, H., Kimura, Y., Takahashi, R., Matsumiya, M., Tamura, K., Futoh, Y., Miyato, H., Saito, S., Yamaguchi, H., Hosoya, Y., Watano, R., Mizukami, H., Sata, N., Kitayama, J. Intraperitoneal administration of adeno-associated virus encoding microRNA-29b for the treatment of peritoneal metastasis. Cancer Gene Ther 31(12):1818-1830, 2024.<\/li>\n\n\n\n<li>Kashiwakura, Y., Nakajima, Y., Horinaka, K., Lopes, T., Furuta, Y., Yamaguchi, Y., Baatartsogt, N., Hayakawa, M., Katakai, Y., Uchiyama, S., Nureki, O., Nogami, K., Ohmori, T.:&nbsp; Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy. bioRxiv 2024.12.05.626963; doi: https:\/\/doi.org\/10.1101\/2024.12.05.626963.<\/li>\n\n\n\n<li>Koyanagi, T., Saga, Y. Takahashi, Y., Tamura, K., Takahashi, S., Taneichi, A., Takei, Y., Mizukami, H., Fujiwara, H.: Forced Vasohibin-1 Expression Increases Paclitaxel Sensitivity of Ovarian Cancer by Inhibiting Microtubule Activity. Cancer Rep (Hoboken) 7: e70100, 2024.<\/li>\n\n\n\n<li>Koyanagi, T., Saga, Y., Takahashi, Y., Tamura, K., Yoshiba, T., Takahashi, S., Taneichi, A., Takei, Y., Mizukami, H., Fujiwara, H.: The role of non-genomic actions of progesterone and its membrane receptor agonist in ovarian cancer cell death. Cancer Rep (Hoboken). 2024, 7: e1934.<\/li>\n\n\n\n<li>Kumagai, S., Nakajima, T., Muramatsu, S.: Intraparenchymal delivery of adeno-associated virus vectors for the gene therapy of neurological diseases. Expert Opin Biol Ther 24(8):773-785, 2024.<\/li>\n\n\n\n<li>Muramatsu, S.: AAV vectors advance cardiac gene therapy while overcoming challenges. Int J Cardiol 1;400:131704, 2024.<\/li>\n\n\n\n<li>Nakano, K., Sadahiro, T., Fujita, R., Isomi, M., Abe, Y., Yamada, Y., Akiyama, T., Honda, S., French, BA., Mizukami, H., Ieda, M.: Development of adeno-associated viral vectors targeting cardiac fibroblasts for efficient in vivo cardiac reprogramming. Stem Cell Reports, 19: 1389-98, 2024.<\/li>\n\n\n\n<li>Noguchi, J., Watanabe, S., Oga, T., Isoda, R., Nakagaki, K., Sakai, K., Sumida, K., Hoshino, K., Saito, K., Miyawaki, I., Sugano, E., Tomita, H., Mizukami, H., Watakabe, A., Yamamori, T., Ichinohe, N.: Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model. Commun Biol 7: 642, 2024.<\/li>\n\n\n\n<li>Sedohara A, Takahashi K, Arai K, Arizono K, Tuvshinjargal K, Saito M, Nakahara F, Tsutsumi T, Ikeuchi K, Adachi E, Yotsuyanagi H:&nbsp; Characterization of mutations in hepatitis B virus DNA isolated from Japanese HBsAg-positive blood donors in 2021 and 2022. Arch Virol. 2024 Apr 18;169(5):103. doi: 10.1007\/s00705-024-06016-4.<\/li>\n\n\n\n<li>Sehara, Y., Hashimotodani, Y., Watano, R., Ohba, K., Uchibori, R., Shimazaki, K., Kawai, K., Mizukami, H.: Adeno-associated Virus-mediated Ezh2 Knockdown Reduced the Increment of Newborn Neurons Induced by Forebrain Ischemia in Gerbil Dentate Gyrus. Mol Neurobiol 61(11): 9623-9632, 2024.<\/li>\n\n\n\n<li>Suzuki, T., Hattori, S., Mizukami, H., Nakajima, R., Hibi, Y., Kato, S., Matsuzaki, M., Miyakawa, T., Ikebe, R., Yamakawa, K.: Inversed effects of Nav1.2 deficiency at medial prefrontal cortex and ventral tegmental area for prepulse inhibition in acoustic startle response. Mol Neurobiol 61: 622-634, 2024.<\/li>\n\n\n\n<li>Togashi, T., Baatartsogt, N., Nagao, Y., Kashiwakura, Y., Hayakawa, M., Hiramoto, T., Fujiwara, T., Morishita, E., Nureki, O., Ohmori, T.: Cure of congenital purpura fulminans via expression of engineered protein C through neonatal genome editing in mice. Arteriosclerosis, Thrombosis, and Vascular Biology: 44(12): 2616-2627, 2024. doi: 10.1161\/ATVBAHA.123.319460.<\/li>\n\n\n\n<li>Yamamoto, Y., Fabbri, C., Okuhara, D., Takagi, R., Kawabata, Y., Katayama, T., Iyori, M., Hasyim, A., Sakamoto, A., Mizukami, H., Shida, H., Lopes, S., Yoshida, S.: A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study. Front Immunol 15:1372584, 2024.<\/li>\n\n\n\n<li>Zainal, KH., Hasyim, AA., Yamamoto, Y., Mizuno, T., Sato, Y., Rasyid, SH., Niikura, M., Abe, YI., Iyori, M., Mizukami, H., Shida, H., Yoshida, S.: A Head-to-Head Comparative Study of the Replication-Competent Vaccinia Virus and AAV1-Based Malaria Vaccine versus RTS,S\/AS01 in Murine Models. Vaccines (Basel) 12: 1155, 2024.<\/li>\n<\/ol>\n<\/div><\/div>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">B. \u5b66\u4f1a\u767a\u8868<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u65e9\u5ddd\u76db\u798e,\u67cf\u5009\u88d5\u5fd7,\u677e\u672c \u5f6c,\u65e9\u5ddd\u88d5\u5b50,\u3000Baatartsogt Nemekhbayar,\u9577\u5c3e\u606d\u5149,\u5927\u68ee \u53f8\uff1a\u809d\u985e\u6d1e\u5185\u76ae\u7d30\u80de\u3092\u6a19\u7684\u3068\u3057\u305f\u8840\u53cb\u75c5A\u907a\u4f1d\u5b50\u6cbb\u7642.\u7b2c86\u56de\u65e5\u672c\u8840\u6db2\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u4eac\u90fd,2024\/10\/11.<\/li>\n\n\n\n<li>\u6797\u3000\u5922\u590f,\u702c\u539f\u5409\u82f1,\u5d0e\u5c71\u5feb\u592b:AAV9\u30d9\u30af\u30bf\u30fc\u5168\u8eab\u6295\u4e0e\u306b\u3088\u308bFabry\u75c5\u30de\u30a6\u30b9\u3078\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u52b9\u679c\uff0e\u7b2c49\u56de\u65e5\u672c\u8133\u5352\u4e2d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u6a2a\u6d5c,2024\/03\/08.<\/li>\n\n\n\n<li>\u67cf\u5009\u88d5\u5fd7,\u4e2d\u5cf6\u7531\u7fd4,Tiago Lopes, Nemekhbayar Baatartsogt,\u9d28\u4e0b\u4fe1\u5f66,\u65e9\u5ddd\u76db\u798e,\u7247\u8c9d\u7950\u5b50,\u91ce\u4e0a\u6075\u55e3,\u5927\u68ee \u53f8\uff1a\u52b9\u679c\u7684\u306a\u8840\u53cb\u75c5A\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u5b9f\u73fe\u3057\u3046\u308b\u6539\u5909\u578b\u7b2cVIII\u56e0\u5b50\u306e\u958b\u767a.\u7b2c46\u56de\u65e5\u672c\u8840\u6813\u6b62\u8840\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u77f3\u5ddd,2024\/06\/13-15.<\/li>\n\n\n\n<li>\u67cf\u5009\u88d5\u5fd7,\u4e2d\u5cf6\u7531\u7fd4,\u53e4\u7530\u52c7\u99ac,\u5c71\u53e3\u7950\u5e0c, Tiago Lopes\uff0cNemekhbayar Baatartsogt,\u65e9\u5ddd\u76db\u798e,\u7247\u8c9d\u7950\u5b50,\u5185\u5c71 \u9032,\u6fe1\u6728 \u7406,\u91ce\u4e0a\u6075\u55e3, \u5927\u68ee \u53f8\uff1a\u6539\u5909\u7b2cVIII\u56e0\u5b50\u3092\u7528\u3044\u305f\u52b9\u679c\u7684\u306a\u8840\u53cb\u75c5A\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u958b\u767a.\u7b2c30\u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u6a2a\u6d5c,2024\/07\/16\u221218.<\/li>\n\n\n\n<li>\u67cf\u5009\u88d5\u5fd7,\u5927\u68ee \u53f8\uff1a\u5148\u5929\u6027\u75be\u60a3\u306b\u5bfe\u3059\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642\u306e\u958b\u767a.\u7b2c30\u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a,\u6a2a\u6d5c,2024\/07\/18.<\/li>\n\n\n\n<li>\u67cf\u5009\u88d5\u5fd7,\u5927\u68ee \u53f8\uff1a\u6539\u5909\u578bFVIII\u3092\u7528\u3044\u305f\u8840\u53cb\u75c5A\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u958b\u767a.\u7b2c97\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5927\u4f1a,\u795e\u5948\u5ddd,2024\/11\/07,\u53e3\u982d.<\/li>\n\n\n\n<li>\u6c34\u4e0a\u6d69\u660e\uff1aAAV\u30d9\u30af\u30bf\u30fc\u958b\u767a\u306e\u73fe\u72b6.\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff13 \u7b2c71\u56de\u65e5\u672c\u30a6\u30a4\u30eb\u30b9\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u540d\u53e4\u5c4b\uff0c2024\/11\/05.<\/li>\n\n\n\n<li>\u91ce\u53e3\u5149\u592e\uff0c\u8c37\u539f\u53f2\u502b\uff0c\u539f\u3000\u5f18\u771f\uff0c\u7a32\u6bdb\u7531\u4f73\uff0c\u4e95\u4e0a\u3000\u8aa0\uff0c\u82b1\u5712\u3000\u8c4a\uff0c\u6a2a\u5c3e\u3000\u9686\uff0c\u672c\u591a\u3000\u65b0\uff1a\u30d6\u30bf\u53d7\u7cbe\u5375\u3078\u306eAAV\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305f\u30ce\u30c3\u30af\u30a4\u30f3\u30d6\u30bf\u306e\u4f5c\u51fa\uff0e\u7b2c117\u56de \u65e5\u672c\u7e41\u6b96\u751f\u7269\u5b66\u4f1a\u5927\u4f1a,\u540d\u53e4\u5c4b\uff0c2024\/09\/23\uff0e<\/li>\n\n\n\n<li>\u91ce\u53e3\u5149\u592e\uff0c\u8c37\u539f\u53f2\u502b\uff0c\u7a32\u6bdb\u7531\u4f73\uff0c\u539f\u3000\u5f18\u771f\uff0c\u4e95\u4e0a\u3000\u8aa0\uff0c\u82b1\u5712\u3000\u8c4a\uff0c\u6a2a\u5c3e\u3000\u9686\uff0c\u672c\u591a\u3000\u65b0\uff1aConditional ablation\u3092\u76ee\u6307\u3057\u305fAAV\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u30ce\u30c3\u30af\u30a4\u30f3\u30d6\u30bf\u306e\u4f5c\u51fa\uff0e\u7b2c47\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a,\u798f\u5ca1\uff0c2024\/12\/05\uff0e<\/li>\n\n\n\n<li>\u5927\u5ead\u8ce2\u4e8c,\u897f\u5c3e\u4f50\u5948\u6075\uff1a\u907a\u4f1d\u5b50\u6cbb\u7642\u306b\u7528\u3044\u308b\u6b21\u4e16\u4ee3\u5206\u5b50\u7279\u7570\u7684AAV\u30d9\u30af\u30bf\u30fc\u306e\u958b\u767a.\u7b2c30\u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u6a2a\u6d5c, 2024\/07\/17.<\/li>\n\n\n\n<li>\u5927\u68ee \u53f8\uff1a\u5148\u5929\u6027\u8840\u6813\u6b62\u8840\u6027\u75be\u60a3\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u30fb\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642.\u65e5\u672c\u5c0f\u5150\u8840\u6db2\u30fb\u304c\u3093\u5b66\u4f1a, \u4eac\u90fd,2024\/12\/14.<\/li>\n\n\n\n<li>\u5927\u68ee \u53f8\uff1a\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u3067\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76, \u7b2c24\u56de\u518d\u751f\u533b\u7642\u5b66\u4f1a\u7dcf\u4f1a,\u65b0\u6f5f,2024\/03\/21.<\/li>\n\n\n\n<li>\u5c0f\u91ce\u5bfa\u96c5\u53f2, \u6751\u677e\u614e\u4e00, \u5c0f\u7267\u5b8f\u6587, \u5c0f\u5742\u3000\u4ec1, \u4e45\u7c73\u6643\u5553:\u5c0f\u5150\u795e\u7d4c\u75be\u60a3\u3078\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u81e8\u5e8a\u5fdc\u7528\u3068\u6cbb\u7642\u4f53\u5236\u6574\u5099\u306b\u5411\u3051\u3066.\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5171\u50ac\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0. \u7b2c66\u56de\u65e5\u672c\u5c0f\u5150\u795e\u7d4c\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u540d\u53e4\u5c4b, 2024\/05\/30.<\/li>\n\n\n\n<li>\u702c\u539f\u5409\u82f1, \u7dbf\u91ce\u4eae\u592a, \u5927\u5ead\u8ce2\u4e8c, \u5cf6\u5d0e\u4e45\u4ec1\u5b50, \u5ddd\u5408\u8b19\u4ecb:\u30b9\u30ca\u30cd\u30ba\u30df\u524d\u8133\u865a\u8840\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u30dd\u30ea\u30b3\u30fc\u30e0\u7fa4\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6025\u6027\u671f\u7d4c\u6642\u7684\u5909\u5316\uff0e\u7b2c49\u56de\u65e5\u672c\u8133\u5352\u4e2d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u6a2a\u6d5c, 2024\/03\/08.<\/li>\n\n\n\n<li>\u702c\u539f\u5409\u82f1, \u7dbf\u91ce\u4eae\u592a, \u5927\u5ead\u8ce2\u4e8c, \u5cf6\u5d0e\u4e45\u4ec1\u5b50, \u5ddd\u5408\u8b19\u4ecb, \u6c34\u4e0a\u6d69\u660e:Ezh2 knockdown reduced post-ischemic increment of neurogenesis in gerbil hippocampus\uff0e\u7b2c65\u56de\u65e5\u672c\u795e\u7d4c\u5b66\u4f1a\u5b66\u8853\u5927\u4f1a,\u6771\u4eac,2024\/06\/01.<\/li>\n\n\n\n<li>\u702c\u539f\u5409\u82f1, \u5927\u5ead\u8ce2\u4e8c, \u7dbf\u91ce\u4eae\u592a, \u535c\u90e8\u5321\u53f8, \u6c34\u4e0a\u6d69\u660e:\u30a2\u30c7\u30ce\u968f\u4f34\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u306e\u30af\u30ed\u30ed\u30db\u30eb\u30e0\u7cbe\u88fd\uff0e\u7b2c30\u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u6a2a\u6d5c,2024\/07\/18.<\/li>\n\n\n\n<li>\u51a8\u6a2b\u670b\u8cb4, \u65e5\u91ce\u667a\u535a, \u5927\u6751\u7d17\u767b\u58eb, \u4e2d\u5ddd\u7dbe\u54c9, \u661f\u91ce \u6e29, \u6fe1\u6728 \u7406, \u5927\u68ee \u53f8\uff1a\u6539\u5909\u3057\u305f\u8d85\u5c0f\u578bAsCas12f\u306b\u3088\u308b\u8840\u53cb\u75c5B\u30de\u30a6\u30b9\u306ein vivo\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642. \u7b2c46\u56de\u65e5\u672c\u8840\u6813\u6b62\u8840\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u77f3\u5ddd,2024\/06\/13.<\/li>\n\n\n\n<li>\u51a8\u6a2b\u670b\u8cb4, \u65e5\u91ce\u667a\u535a, \u5927\u6751\u7d17\u767b\u58eb, \u4e2d\u5ddd\u7dbe\u54c9, Nemekhbayar Baatartsogt, \u67cf\u5009\u88d5\u5fd7, Khishigjargal Batjargal, \u65e9\u5ddd\u76db\u798e, \u661f\u91ce \u6e29, \u6fe1\u6728 \u7406, \u5927\u68ee \u53f8\uff1a\u5358\u4e00AAV\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u809d\u81d3\u3092\u6a19\u7684\u3068\u3057\u305f\u907a\u4f1d\u5b50\u30ce\u30c3\u30af\u30a4\u30f3\u6280\u8853\u306e\u6700\u9069\u5316. \u7b2c30\u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u6a2a\u6d5c,2024\/07\/16.\u3000<\/li>\n\n\n\n<li>\u6708\u7530\u3000\u8cb4\u548c\u5b50.:\u795e\u7d4c\u96e3\u75c5\u306b\u5bfe\u3059\u308bAAV\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305f\u907a\u4f1d\u5b50\u6cbb\u7642\u958b\u767a.\u7b2c66\u56de\u65e5\u672c\u5c0f\u5150\u795e\u7d4c\u5b66\u4f1a,\u540d\u53e4\u5c4b,2024\/05\/30-06\/01.<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb, \u5927\u5dba\u3000\u8b19, \u5cf0\u91ce\u7d14\u4e00, \u5c0f\u6fa4\u656c\u4e5f\uff1aCAR-T\u7d30\u80de\u9078\u629e\u7684\u306a\u5897\u6b96\u5236\u5fa1\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a. \u7b2c16\u56de\u8840\u6db2\u75be\u60a3\u514d\u75ab\u7642\u6cd5\u5b66\u4f1a, \u4eac\u90fd, 2024\/7\/26-27.\uff08\u6284\u9332\u96c6p.81, JST\u8cc7\u6599\u756a\u53f7\uff1aF2997A\uff09<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb, \u5927\u5dba\u3000\u8b19, \u5cf0\u91ce\u7d14\u4e00, \u5c0f\u6fa4\u656c\u4e5f\uff1aCAR-T\u7d30\u80de\u9078\u629e\u7684\u306a\u5897\u6b96\u5236\u5fa1\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a. \u7b2c863\u56de\u8840\u6db2\u75be\u60a3\u514d\u75ab\u7642\u6cd5\u5b66\u4f1a, \u4eac\u90fd, 2024\/7\/26-27.\uff08ROMBUNNO.P-3375 (WEB ONLY), JST\u8cc7\u6599\u756a\u53f7\uff1aU0661A\uff09<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5, \u5b89\u6e08\u9054\u4e5f, \u5ddd\u4e0a\u4eae, \u5fb3\u5c71\u525b\u58eb, AHMED Razan, TORIZAL F Gandhi, \u77f3\u4e95\u79c0\u6a39, \u5c0f\u677f\u6a4b\u7d00\u901a\uff1aGene Therapy for Mybpc3 Mutant Cardiomyopathy Models, \u7b2c88\u56de\u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u795e\u6238, 2024\/03\/10.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u591a\u80fd\u6027\u5e79\u7d30\u80de\u7531\u6765\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u5316\u3068\u75be\u60a3\u30e2\u30c7\u30eb\u3078\u306e\u6311\u6226, \u7b2c101\u56de\u65e5\u672c\u751f\u7406\u5b66\u4f1a\u5927\u4f1a,\u798f\u5ca1, 2024\/03\/29.<\/li>\n\n\n\n<li>Ahmed, E.R., Chanthra, N., Iwabuchi, A.K., Tokuyama, T., Uosaki, H.: Mitochondrial Cardiomyopathy Patient-Derived Induced Pluripotent Stem Cells Recaptured Key Cardiac Features of the Disease. CVMW2024, Tokyo, Japan, &nbsp;2024\/12\/07.<\/li>\n\n\n\n<li>Chanthra, N., Ahmed, E.R., Torizal, F.G., Tokuyama, T., Uosaki, H.: Identification of Transcriptional Factors and Nuclear Receptors Regulating Cardiomyocyte Maturation in vitro. Weinstein Conference, Montreal, Canada, 2024\/05\/15.<\/li>\n\n\n\n<li>Kashiwakura, Y., Nakajima, Y., Lopes,T., Baatartsogt, N., Kamoshita, N., Hayakawa, M., Katakai, Y., Nogami, K., Ohmori, T.: Development of engineered factor VIII for effective hemophilia A gene therapy. the International Society on Thrombosis and Haemostasis 2024 Congress, Thailand, 2024\/06\/22-26.<\/li>\n\n\n\n<li>Kashiwakura, Y., Nakajima, Y., Furuta, Y., Yamaguchi, Y., Horinaka, K., Lopes, T., Baatartsogt, N., Hayakawa, M., Katakai, Y., Nureki, O., Uchiyama, S., Nogami, K., Ohmori, T.: The engineered coagulation factor VIII for effective hemophilia A gene therapy. \u7b2c86\u56de\u65e5\u672c\u8840\u6db2\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, Kyoto, Japan, 2024\/10\/11\u221213.<\/li>\n\n\n\n<li>Ohba, K., Zappala, A., Nishio, S., Ofusa, Y., Mizukami, H.: The possibility of novel adeno-associated virus (AAV) vector production system for gene therapy. The 31st ESGCT Annual Congress, Rome, Italy, 2024\/10\/22-25.<\/li>\n\n\n\n<li>Ohmori, T.: Novel approaches of genome editing for treatment and diagnosis of genetic diseases. The 27th Annual meeting of American Society of Gene and Cell Therapy (Symposium), Chicago, USA, 2024\/05\/08.<\/li>\n\n\n\n<li>Sehara, Y., Hashimotodani, Y., Shimazaki, K., Kawai, K.: Temporal profile of Ezh2 in gerbil dentate gyrus in acute phase of forebrain ischemia. Annual Meeting of Society for Neuroscience 2024, Chicago, USA, 2024\/10\/05-09.<\/li>\n\n\n\n<li>Togashi, T., Hino, T., Omura, S.N., Nakagawa, R., Hoshino, A., Nureki, O., Ohmori, T.: Knock-in genome editing therapy with a single AAV vector harboring an engineered AsCas12f for hemophilia B in mice. The 32nd Congress of the International Society on Thrombosis and Haemostasis (ISTH)., Thailand, 2024\/06\/22-26.<\/li>\n\n\n\n<li>Togashi, T., Hino, T., Omura, S.N., Nakagawa, R., Baatartsogt, N., Kashiwakura, Y., Batjargal, K., Hayakawa, M., Hoshino, A., Nureki, O., Ohmori, T.: Knock-in genome editing therapy with a single AAV vector for hemophilia B in mice. \u7b2c86\u56de\u65e5\u672c\u8840\u6db2\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, Kyoto, Japan, &nbsp;2024\/10\/12.<\/li>\n\n\n\n<li>Tokuyama, T., Tani, H., Wakigawa, T., Iwabuchi, A.K., Torizal, F.G., Ahmed, E.R., Wei, FY., Iwasaki, S., Uosaki, H.: Restoring Mitochondrial Function in KARS1-Mutant iPSCs through Taurine-Induced tRNA Stabilization. 29th tRNA conference, Kanazawa, Japan, 2024\/11\/20.<\/li>\n\n\n\n<li>Tokuyama, T., Tani, H., Wakigawa, T., Iwabuchi, A.K., Torizal, F.G., Ahmed, E.R., Wei, FY., Iwasaki, S., Uosaki, H.: Taurine-Mediated tRNA Stabilization Enhances Mitochondrial Function in KARS1-Mutant iPSCs. CVMW2024, Tokyo, Japan, 2024\/12\/07.<\/li>\n\n\n\n<li>Tsukida, K., Muramatsu, S., Osaka, H., Muramatsu, K.: Gene transfer of WDR45 restored ferritinophagy in SENDA\/BPAN patient-derived cells\uff0e The 31st ESGCT Annual Congress, Rome, Italy,2024\/10\/22-25.<\/li>\n\n\n\n<li>Uosaki, H.: Where are we with the gene therapy for cardiomyopathy, MIS-Korea, \u97d3\u56fd, 2024\/03\/08.<\/li>\n\n\n\n<li>Uosaki, H., Anzai, T., Kawakami, R., Tokuyama, T., Ahmed, E.R., Torizal, F.G., Nagao, Y., Nishizono, H., Koitabashi, N.: Development of Cardiomyopathy Variant Knock-in Mouse Strains for Gene Therapy Proof-of-Concept. ASGCT, Baltimore, MD, USA, 2024\/05\/08.<\/li>\n\n\n\n<li>Watano, R., Ohba, K., Sehara, Y., Saga, Y., Urabe, M., Mizukami, H.: The dissociation constant is one of the limitations for cell-based neutralizing antibody assays against AAV capsids. European society of gene and cell therapy 31th Congress, Rome, Italy, 2024\/10\/22-25.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">C. \u8457\u66f8\u30fb\u7dcf\u8aac<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u82b1\u5712\u3000\u8c4a:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; \u30d6\u30bf\u30b2\u30ce\u30e0\u7de8\u96c6\u2015\u7570\u7a2e\u79fb\u690d\u3078\u306e\u5fdc\u7528, \u5b9f\u9a13\u533b\u5b66 2024 Mar 19; 42(6): 897-901<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00: \u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7(ALS)\u306eUp to Date AAV\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308bALS\u306e\u907a\u4f1d\u5b50\u6cbb\u7642.\u3000\u30d5\u30a1\u30eb\u30de\u30b7\u30a260(5): 419-423, 2024.<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb\uff1aCAR-T\u7d30\u80de\u7642\u6cd5\u306e\u6709\u52b9\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306e\u8ab2\u984c\u3068\u6226\u7565. \u81e8\u5e8a\u8840\u6db2\uff1b65 (6\uff09:597-602, 2024.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">D. \u7279\u8a31<\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u540d\u79f0\uff1a\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u65b9\u6cd5\u3001\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u5ea6\u8a55\u4fa1\u65b9\u6cd5\u3001\u6210\u719f\u5fc3\u7b4b\u7d30\u80de\u306e\u9806\u5316\u65b9\u6cd5\u3001\u5fc3\u7b4b\u7d30\u80de\u6210\u719f\u5ea6\u8a55\u4fa1\u88c5\u7f6e\u3001\u5fc3\u7b4b\u7d30\u80de\u6210\u719f\u5ea6\u8a55\u4fa1\u30d7\u30ed\u30b0\u30e9\u30e0\u3001\u53ca\u3073\u5fc3\u7b4b\u7d30\u80de\u6210\u719f\u30ad\u30c3\u30c8<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u767a\u660e\u8005\uff1a\u9b5a\u5d0e\u82f1\u6bc5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u51fa\u9858\u4eba\uff1a\u5b66\u6821\u6cd5\u4eba\u81ea\u6cbb\u533b\u79d1\u5927\u5b66<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u8a31\u756a\u53f7\uff1a\u7b2c7514546\u53f7<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u767b\u9332\u65e5\uff1a2024\/7\/3<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u540d\u79f0\uff1aAdeno-associated virus virion for treatment of Tay-Sachs disease and Sandhoff disease<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u767a\u660e\u8005\uff1a\u4f0a\u85e4\u5b5d\u53f8\u3001\u8fbb\u3000\u5927\u8f14\u3001\u6751\u677e\u614e\u4e00\u3001\u6d45\u4e95\u514b\u4ec1<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u51fa\u9858\u4eba\uff1a\u5fb3\u5cf6\u5927\u5b66\u3001\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u3001\uff08\u682a\uff09\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u6240<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u8a31\u756a\u53f7\uff1a\u7c73\u56fd\u7279\u8a31 No. 12,064,460 B2<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u767b\u9332\u65e5\uff1a2024\/7\/8<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u540d\u79f0\uff1a\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u3001\u6210\u719f\u5fc3\u7b4b\u7d30\u80de\u88fd\u9020\u65b9\u6cd5\u3001\u53ca\u3073\u5fc3\u7b4b\u7d30\u80de\u6210\u719f\u30ad\u30c3\u30c8<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u767a\u660e\u8005\uff1a\u9b5a\u5d0e\u82f1\u6bc5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u51fa\u9858\u4eba\uff1a\u5b66\u6821\u6cd5\u4eba\u81ea\u6cbb\u533b\u79d1\u5927\u5b66<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u8a31\u756a\u53f7\uff1a\u7b2c7537726\u53f7 \u767b\u9332\u65e5\uff1a2024\/8\/13<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">E. \u305d\u306e\u4ed6<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u67cf\u5009\u88d5\u5fd7, \u5927\u68ee\u3000\u53f8\uff1a\u6539\u5909\u7b2cVIII\u56e0\u5b50\u3092\u7528\u3044\u305f\u8840\u53cb\u75c5A\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u958b\u767a, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>&nbsp;\u718a\u8c37\u771f\u4e00, \u6751\u677e\u614e\u4e00\uff1a\u3066\u3093\u304b\u3093\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u958b\u767a, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>&nbsp;\u4e45\u7c73\u6643\u5553\uff1a\u533b\u85ac\u54c1\uff0f\u518d\u751f\u533b\u7642\u7b49\u88fd\u54c1\u3068\u3057\u3066\u306emRNA\uff1a\u6700\u65b0\u52d5\u5411, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>&nbsp;\u6c34\u4e0a\u6d69\u660e, \u7dbf\u91ce\u4eae\u592a\uff1aAAV\u30d9\u30af\u30bf\u30fc\u306b\u5bfe\u3059\u308b\u514d\u75ab\u53cd\u5fdc\u306b\u3064\u3044\u3066, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>\u3000\u6751\u677e\u4e00\u6d0b\uff1a\u5148\u5929\u4ee3\u8b1d\u7570\u5e38\u75c7\u306b\u5bfe\u3059\u308b\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u3000\u907a\u4f1d\u5b50\u6cbb\u7642\u3068\u306f.2023\u5e74\u5ea6\u5148\u5929\u4ee3\u8b1d\u7570\u5e38\u75c7\u60a3\u8005\u4f1a\u30d5\u30a9\u30fc\u30e9\u30e0,\u6771\u4eac,2024\/01\/27<\/li>\n\n\n\n<li>&nbsp;\u6751\u677e\u4e00\u6d0b, \u5c71\u5f62\u5d07\u502b\uff1a\u5148\u5929\u4ee3\u8b1d\u7570\u5e38\u306ein vivo \u907a\u4f1d\u5b50\u6cbb\u7642\u958b\u767a, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>&nbsp;\u6751\u677e\u614e\u4e00\uff1aAAV\u30d9\u30af\u30bf\u30fc\u304c\u62d3\u304f\u96e3\u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\uff5e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3092\u4e2d\u5fc3\u3068\u3057\u3066. \u4e5d\u5dde\u795e\u7d4c\u5185\u79d1\u75be\u60a3Web\u30bb\u30df\u30ca\u30fc, Web, 2024\/02\/01.<\/li>\n\n\n\n<li>&nbsp;\u6751\u677e\u614e\u4e00\uff1aEducation Session\u8133\u75be\u60a3\u306e\u907a\u4f1d\u5b50\u6cbb\u7642. \u7b2c14\u56de\u7fa4\u99ac\u5927\u5b66\u672a\u6765\u5148\u7aef\u7814\u7a76\u6a5f\u69cb\u56fd\u969b\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0, \u7fa4\u99ac\u5927\u5b66, 2024\/02\/14.<\/li>\n\n\n\n<li>&nbsp;\u6751\u677e\u614e\u4e00\uff1aAAV\u30d9\u30af\u30bf\u30fc\u304c\u62d3\u304f\u96e3\u75c5\u6cbb\u7642. \u90fd\u533b\u5b66\u7814\u30bb\u30df\u30ca\u30fc, \u6771\u4eac, 2024\/02\/27.<\/li>\n\n\n\n<li>&nbsp;\u6751\u677e\u614e\u4e00\uff1a\u30a2\u30c7\u30ce\u968f\u4f34\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305f\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u3081\u3050\u308b\u8a71\u984c, \u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u30fb\u5148\u5929\u6027\u4ee3\u8b1d\u7570\u5e38\u75c7\u306a\u3069. \u75c5\u56e0\u30fb\u75c5\u614b\u89e3\u660e\u3092\u76ee\u6307\u3057\u305f\u9175\u7d20\u7814\u7a76, \u304a\u8336\u306e\u6c34\u5973\u5b50\u5927\u5b66, 2024\/02\/29.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6cbb\u7642. \u4eac\u90fd\u5927\u5b66iPS\u7d30\u80de\u7814\u7a76\u6240\u7b2c20\u56de\u5e79\u7d30\u80de\u533b\u5b66\u30bb\u30df\u30ca\u30fc, \u4eac\u90fd\u5927\u5b66iPS\u7d30\u80de\u7814\u7a76\u6240, 2024\/04\/23.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV\u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6cbb\u7642 up to date \uff5e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3092\u4e2d\u5fc3\u3068\u3057\u3066. \u795e\u7d4c\u5909\u6027\u75be\u60a3\u306e\u6700\u524d\u7dda in\u6a2a\u6d5c, Web, 2024\/04\/25.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV\u30d9\u30af\u30bf\u30fc\u304c\u62d3\u304f\u907a\u4f1d\u5b50\u6cbb\u7642 -\u8ab2\u984c\u3068\u6311\u6226-. LINK-J\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 \u5275\u85ac\u306e\u30d5\u30ed\u30f3\u30c6\u30a3\u30a22024, \u6771\u4eac, 2024\/06\/24.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u6700\u65b0\u6cbb\u7642. \u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3068\u8133\u30fb\u795e\u7d4c\u306e\u75c5\u6c17\u306b\u3064\u3044\u3066\u77e5\u308b\u30bb\u30df\u30ca\u30fcin\u5b87\u90fd\u5bae, \u6803\u6728, 2024\/07\/14.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u30fbALS\u306e\u6700\u65b0\u6cbb\u7642. JMU-CGTR\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7 &#8211; \u907a\u4f1d\u5b50\u6cbb\u7642\u3063\u3066\u4f55\uff1f, \u6803\u6728, 2024\/10\/05.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u767a\u5c55\u3059\u308b\u96e3\u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642. IRUD\u73ed\u4f1a\u8b70, \u6771\u4eac, 2024\/12\/13.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV\u30d9\u30af\u30bf\u30fc\u304c\u62d3\u304f\u795e\u7d4c\u5909\u6027\u75be\u60a3\u306e\u907a\u4f1d\u5b50\u6cbb\u7642. ACTjapan\u30d5\u30a9\u30fc\u30e9\u30e0 \u30a2\u30ab\u30c7\u30df\u30a2\u81e8\u5e8a\u958b\u767aUpdate \uff5e\u795e\u7d4c\u5909\u6027\u75be\u60a3\u6cbb\u7642\u306e\u30d6\u30ec\u30a4\u30af\u30b9\u30eb\u30fc\uff5e \u7279\u5225\u8b1b\u6f14, \u5927\u962a\u5e02, 2024\/12\/18.<\/li>\n\n\n\n<li>\u4e2d\u539f\u53f2\u96c4, \u82b1\u5712\u3000\u8c4a\uff1a\u9020\u8840\u5e79\u7d30\u80de\u306b\u5bfe\u3059\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u52b9\u7387\u306e\u5411\u4e0a, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>\u5927\u5ead\u8ce2\u4e8c\uff1a\u30a6\u30a4\u30eb\u30b9\u306e\u529f\u7f6a\u301c\u611f\u67d3\u75c7\u30fb\u30d1\u30f3\u30c7\u30df\u30c3\u30af\u304b\u3089\u907a\u4f1d\u5b50\u6cbb\u7642\u307e\u3067\u301c, \u30b9\u30fc\u30d1\u30fc\u30b5\u30a4\u30a8\u30f3\u30b9\u30b9\u30af\u30fc\u30eb(SSH) \u6803\u6728\u9ad8\u6821\u7279\u5225\u6388\u696d, \u6803\u6728, 2024\/03\/15<\/li>\n\n\n\n<li>\u5927\u5dba\u3000\u8b19\uff1a\u8840\u6db2\u304c\u3093\u306e\u907a\u4f1d\u5b50\u6cbb\u7642, JMU-CGTR\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7 &#8211; \u907a\u4f1d\u5b50\u6cbb\u7642\u3063\u3066\u4f55\uff1f, \u6803\u6728, 2024\/10\/05.<\/li>\n\n\n\n<li>\u5927\u68ee\u3000\u53f8\uff1a\u907a\u4f1d\u5b50\u6cbb\u7642\u3063\u3066\u4f55\uff1f, JMU-CGTR\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7 &#8211; \u907a\u4f1d\u5b50\u6cbb\u7642\u3063\u3066\u4f55\uff1f, \u6803\u6728, 2024\/10\/05.<\/li>\n\n\n\n<li>\u5c0f\u5742\u3000\u4ec1, \u4e2d\u6751\u5e78\u6075\uff1aAAV\u30d9\u30af\u30bf\u30fc\u306edelivery\u3068distribution\u306e\u691c\u8a0e, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>\u5c0f\u6fa4\u656c\u4e5f\uff1a\u30a4\u30f3\u30c8\u30ed\u30c0\u30af\u30b7\u30e7\u30f3\uff1a\u81ea\u6cbb\u533b\u5927\u7814\u7a76\u958b\u767a\u8ab2\u984c\u306e\u7d39\u4ecb\u3068\u6700\u8fd1\u306e\u8a71\u984c, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>\u5c0f\u6fa4\u656c\u4e5f\uff1a\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u3068\u907a\u4f1d\u5b50\u6cbb\u7642, JMU-CGTR\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7 &#8211; \u907a\u4f1d\u5b50\u6cbb\u7642\u3063\u3066\u4f55\uff1f, \u6803\u6728, 2024\/10\/05.<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb, \u5927\u5dba\u3000\u8b19\uff1aCAR-T\u7642\u6cd5\u306e\u305f\u3081\u306e\u9078\u629e\u7684\u5236\u5fa1\u907a\u4f1d\u5b50\uff08SRG\uff09\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>\u535c\u90e8\u5321\u53f8\uff1aAAV\u3068\u30d0\u30ad\u30e5\u30ed\u30a6\u30a4\u30eb\u30b9\u300020\u5e74\u306e\u6b69\u307f, \u7b2c6\u56de\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e02024, \u6803\u6728, 2024\/02\/05.<\/li>\n\n\n\n<li>\u5c71\u5f62\u5d07\u502b\uff1a\u5c0f\u5150\u907a\u4f1d\u5b50\u75be\u60a3\u306e\u907a\u4f1d\u5b50\u6cbb\u7642, JMU-CGTR\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7 &#8211; \u907a\u4f1d\u5b50\u6cbb\u7642\u3063\u3066\u4f55\uff1f, \u6803\u6728, 2024\/10\/05.<\/li>\n<\/ol>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group accordion_ttl\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading\">2023\u5e74<\/h4>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion_wrap\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h5 class=\"wp-block-heading\">A. \u539f\u8457\u8ad6\u6587<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Hino T, Omura SN, Nakagawa R, Togashi T, Takeda SN, Hiramoto T, Tasaka S, Hirano H, Tokuyama T, Uosaki H, Ishiguro S, Kagieva M, Yamano H, Ozaki Y, Motooka D, Mori H, Kirita Y, Kise Y, Itoh Y, Matoba S, Aburatani H, Yachie N, Karvelis T, Siksnys V, Ohmori T, Hoshino A, and Nureki O: An AsCas12f-based compact genome editing tool derived by deep mutational scanning and structural analysis. Cell. 2023 Sep 22: S0092-8674(23)00963-7. doi: 10.1016\/j.cell.2023.08.031. Online ahead of print.<\/li>\n\n\n\n<li>Hiramoto T, Kashiwakura Y, Hayakawa M, Baatartsogt N, Kamoshita N, Abe T, Inaba H, Nishimasu H, Uosaki H, Hanazono Y, Nureki O, Ohmori T.: PAM-flexible Cas9-mediated base editing of a hemophilia B mutation in induced pluripotent stem cells. Commun Med (Lond). 2023 Apr 19;3(1):56. doi: 10.1038\/s43856-023-00286-w.<\/li>\n\n\n\n<li>Miyamoto M, Kannan S, Anderson MJ, Liu X, Suh D, Htet M, Li B, Katani T, Murphy S, Tampakakis E, Lewandoski M, Andersen P, Uosaki H, Kwon C.: Cardiac progenitors instruct second heart field fate through Wnts. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217687120. doi: 10.1073\/pnas.2217687120. Epub 2023 Jan 17.<\/li>\n\n\n\n<li>Watanabe C, Osaka H, Watanabe M, Miyauchi A, Jimbo EF, Tokuyama T, Uosaki H, Kishita Y, Okazaki Y, Onuki T, Ebihara T, Aizawa K, Murayama K, Ohtake A, Yamagata T.: Total and reduced\/oxidized forms of coenzyme Q10 in fibroblasts of patients with mitochondrial disease. Mol Genet Metab Rep. 2023 Jan 3:34:100951. doi: 10.1016\/j.ymgmr.2022.100951. eCollection 2023 Mar.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">B. \u5b66\u4f1a\u767a\u8868<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u5c0f\u677f\u6a4b\u7d00\u901a, \u5ddd\u4e0a\u4eae, \u5fb3\u5c71\u525b\u58eb, \u5b89\u6e08\u9054\u4e5f, Ahmed Ranzan, Torizal Fuad Gandhi, \u9577\u5c3e\u606d\u5149, \u9b5a\u5d0e\u82f1\u6bc5, \u77f3\u4e95\u79c0\u6a39: \u30d2\u30c8\u80a5\u5927\u578b\u5fc3\u7b4b\u75c7\u907a\u4f1d\u5b50\u5909\u7570\u30ce\u30c3\u30af\u30a4\u30f3\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306b\u3088\u308b\u75c5\u7684\u306a\u5fc3\u81d3\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u306e\u6539\u5584, \u7b2c71\u56de\u65e5\u672c\u5fc3\u81d3\u75c5\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u6771\u4eac, 2023\/9\/8.<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u6211\u304c\u56fd\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u95a2\u9023\u898f\u5236\uff0e\u7b2c65\u56de\u65e5\u672c\u5c0f\u5150\u795e\u7d4c\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff0c\u5ca1\u5c71\uff0c2023 \u5e74 5 \u6708 26 \u65e5\uff0e<\/li>\n\n\n\n<li>\u9b5a\u5d0e \u82f1\u6bc5: \u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u304b\u3089\u898b\u305f\u5fc3\u7b4b\u7d30\u80de\u3068\u76ae\u819a, \u7b2c11\u56de\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u30fb\u514d\u75ab\u3068\u76ae\u819a\u3092\u52c9\u5f37\u3059\u308b\u4f1a, \u6771\u4eac, 2023\/2\/11.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5, \u5b89\u6e08\u9054\u4e5f, \u5ddd\u4e0a\u4eae, \u5fb3\u5c71\u525b\u58eb, AHMED Razan, TORIZAL F Gandhi,\u9577\u5c3e\u606d\u5149, \u77f3\u4e95\u79c0\u6a39, \u5c0f\u677f\u6a4b\u7d00\u901a: \u80a5\u5927\u578b\u5fc3\u7b4b\u75c7\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u3068\u75c5\u7684\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u306e\u6291\u5236, \u7b2c29\u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u5927\u962a, 2023\/9\/11.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5: \u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u3092\u53f8\u308b\u8ee2\u5199\u30cd\u30c3\u30c8\u30ef\u30fc\u30af, \u7b2c46\u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a\uff08\u516c\u52df\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\u3001\u6307\u5b9a\u6f14\u984c\uff09, \u795e\u6238, 2023\/12\/7.<\/li>\n\n\n\n<li>Nawin Chanthra, \u9b5a\u5d0e\u82f1\u6bc5: ES\/iPS \u7d30\u80de\u7531\u6765\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u5316\u3068\u305d\u306e\u751f\u7406\u5b66\u7684\u7279\u6027, \u751f\u7406\u7814\u7814\u7a76\u4f1a, \u5ca1\u5d0e, 2023 \u5e7410 \u670812-13 \u65e5.<\/li>\n\n\n\n<li>Hideki Uosaki: Cardiomyopathy mouse models for the development of gene therapy. MIS-KOREA, Seoul, \u97d3\u56fd, 2023\/3\/2-3.<\/li>\n\n\n\n<li>Hideki Uosaki: Cardiomyopathy Disease Models with Matured iPSC- derived Cardiomyocytes. Cardiovascular Bioenginnering (CVBE) Symposium 2023, Kyoto, 2023\/5\/31.<\/li>\n\n\n\n<li>Munkh-Erdene Natsagdorj, Hiromasa Hara, Suvd Byambaa, Fumio Nakahara,Yasumitsu Nagao, Hideki Uosaki, Yutaka Hanazono.: Development of new strain of immunodeficient mice for pig-to-mouse xenotransplantation. \u7b2c25\u56de\u7570\u7a2e\u79fb\u690d\u7814\u7a76\u4f1a, \u611b\u77e5, 2023\/2\/18.<\/li>\n\n\n\n<li>Nawin Chanthra, Hideki Uosaki: Hormone and Nuclear Receptor Activations Enhance Cardiomyocyte Maturation and Improve Fidelity of Using PSC-CMs as a Mitochondrial Disease Model. \u7b2c87\u56de\u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u3001\u30d7\u30ec\u30ca\u30ea\u30fc, \u798f\u5ca1, 2023\/3\/12.<\/li>\n\n\n\n<li>Norimichi Koitabashi, Ryo Kawakami, Takeshi Tokuyama, Razan E Ahmed, Fuad Gandhi Torizal, Tatsuya Anzai, Yasumitsu Nagao, Hideki Ishii, Hideki Uosaki: Gene Therapy Improves Pathological Cardiac Remodeling in Human Hypertrophic Cardiomyopathy Gene Variant Knock-in Mice. AHA, Philadelphia, USA, 2023\/11\/1.<\/li>\n\n\n\n<li>Razan E Ahmed, Nawin Chanthra, Kumiko A Iwabuchi, Takeshi Tokuyama, Hideki Uosaki: Maturation Culture Exaggerated Disease Phenotype in Mitochondrial Cardiomyopathy iPSC-derived Cardiomyocytes. Weinstein Conference, San Diego, USA, 2023\/5\/4.<\/li>\n\n\n\n<li>Razan E Ahmed, Nawin Chanthra, Kumiko A Iwabuchi, Takeshi Tokuyama, Hideki Uosaki: Combinations of Nuclear Receptor Activations Revealed Disease Phenotype in iPSC-CMs Derived from Patients with Mitochondrial Cardiomyopathy. Cardiovascular Bioenginnering (CVBE) Symposium 2023, Kyoto, 2023\/5\/30.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">C. \u8457\u66f8\u30fb\u7dcf\u8aac<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u907a\u4f1d\u5b50\u6cbb\u7642\u88fd\u54c1\u958b\u767a\u2014\u2014\u30a2\u30ab\u30c7\u30df\u30a2\u304b\u3089\u307f\u305f\u73fe\u72b6\u306e\u8ab2\u984c. \u533b\u5b66\u306e\u3042\u3086\u307f 285(5)495-499, 2023.<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u6211\u304c\u56fd\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u7528\u88fd\u54c1\u85ac\u4e8b\u627f\u8a8d. \u907a\u4f1d\u5b50\u6cbb\u7642\u958b\u767a\u7814\u7a76\u30cf\u30f3\u30c9\u30d6\u30c3\u30af\u7b2c 2 \u7248\uff08\u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u3000\u7de8\u3001\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001\u6771\u4eac\uff09\u3001p579-583\u30012023.<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u6cd5\u4ee4\u30fb\u6307\u91dd\u30ea\u30f3\u30af.\u907a\u4f1d\u5b50\u6cbb\u7642\u958b\u767a\u7814\u7a76\u30cf\u30f3\u30c9\u30d6\u30c3\u30af\u7b2c 2 \u7248\uff08\u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u3000\u7de8\u3001\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001\u6771\u4eac\uff09\u3001p717-721\u30012023.<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553:\u65b0\u85ac\u958b\u767a\u306e\u5404\u6bb5\u968e\u306b\u304a\u3051\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u306e\u6d3b\u7528.\u30b2\u30ce\u30e0\u7de8\u96c6\u306e\u6700\u65b0\u6280\u8853\u3068\u533b\u85ac\u54c1\u30fb\u907a\u4f1d\u5b50\u6cbb\u7642\u30fb\u8fb2\u696d\u30fb\u6c34\u755c\u7523\u7269\u30fb\u6709\u7528\u7269\u8cea\u751f\u7523\u3078\u306e\u6d3b\u7528\uff0c\u6280\u8853\u60c5\u5831\u5354\u4f1a\uff0c2023, 61-68.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">D. \u7279\u8a31<\/h5>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">E. \u305d\u306e\u4ed6<\/h5>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group accordion_ttl\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading\">2022\u5e74<\/h4>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion_wrap\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h5 class=\"wp-block-heading\">A. \u539f\u8457\u8ad6\u6587<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Chino K, Izuo N, Noike H, Uno K, Kuboyama T, Tohda C, Muramatsu S, Nitta A.: Shati\/Nat8l Overexpression Improves Cognitive Decline by Upregulating Neuronal Trophic Factor in Alzheimer&#8217;s Disease Model Mice. Neurochem Res 47(9):2805-2814, 2022.<\/li>\n\n\n\n<li>Ciancia M, Rataj-Baniowska M, Zinter N, Baldassarro VA, Fraulob V, Charles AL, Alvarez R, Muramatsu S, de Lera AR, Geny B, Doll\u00e9 P, Niewiadomska-Cimicka A, Kr\u0119\u017cel W.: Retinoic acid receptor beta protects striatopallidal medium spiny neurons from mitochondrial dysfunction and neurodegeneration. Prog Neurobiol 212:102246, 2022.<\/li>\n\n\n\n<li>Hikiami R, Morimura T, Ayaki T, Tsukiyama T, Morimura N, Kusui M, Wada H, Minamiyama S, Shodai A, Asada-Utsugi M, Muramatsu S, Ueki T, Takahashi R, Urushitani M.: Conformational change of RNA-helicase DHX30 by ALS\/FTD-linked FUS induces mitochondrial dysfunction and cytosolic aggregates. Sci Rep 12(1):16030, 2022.<\/li>\n\n\n\n<li>Hwu PW, Muramatsu S, Chien YH, Byrne BJ.: Advanced therapeutic strategy for hereditary neuromuscular diseases. Mol Ther 30(1):12-13, 2022.<\/li>\n\n\n\n<li>Hwu PW, Muramatsu S, Gidoni-Ben-Zeev B.: Reduced Immunogenicity of Intraparenchymal Delivery of Adeno-Associated Virus Serotype 2 Vectors: Brief Overview. Curr Gene Ther 22(3):185-190, 2022.<\/li>\n\n\n\n<li>Ishii A, Matsuba Y, Mihira N, Kamano N, Saito T, Muramatsu S, Yokosuka M, Saido TC, Hashimoto S.: Tau-binding protein PRMT8 facilitates vacuole degeneration in the brain. J Biochem 172(4):233-243, 2022.<\/li>\n\n\n\n<li>Ishikawa H, Hayakawa M, Baatartsogt N, Kakizawa N, Ohto-Ozaki H, Maruyama T, Miura K, Suzuki K, Rikiyama T, Ohmori T.: I\u03baB\u03b6 Regulates the Development of Nonalcoholic Fatty Liver Disease through the Attenuation of Hepatic Steatosis in Mice. Sci Rep 12(1): 11634, 2022.<\/li>\n\n\n\n<li>Kambhampati S, Murphy S, Uosaki H, Kwon C.: Cross-organ transcriptomic comparison reveals universal factors during maturation. J Comput Biol. Sep;29(9):1031-1044, 2022.<\/li>\n\n\n\n<li>Kashiwakura Y, Baatartsogt N, Yamazaki S, Nagao A, Amano K, Suzuki N, Matsushita T, Sawada A, Higasa S, Yamasaki N, Fujii T, Ogura T, Takedani H, Taki M, Matsumoto T, Yamanouchi J, Sakai M, Nishikawa M, Yatomi Y, Yada K, Nogami K, Watano R, Hiramoto T, Hayakawa M, Kamoshita N, Kume A, Mizukami H, Ishikawa S, Sakata Y, Ohmori T.: The seroprevalence of neutralizing antibodies against the adeno-associated virus capsids in Japanese hemophiliacs. Mol Ther Methods Clin Dev 27: 404-414, 2022.<\/li>\n\n\n\n<li>Kowalski WJ, Garcia-Pak IH, Li W, Uosaki H, Tampakakis E, Zou J, Ling Y, Patterson K, Kwon C, Mukoyama Y.: Sympathetic neurons regulate cardiomyocyte maturation in culture. Front Cell Dev Biol. Mar 11:10:850645, 2022.<\/li>\n\n\n\n<li>Kusui Y, Izuo N, Uno K, Ge B, Muramatsu S, Nitta A.: Knockdown of Piccolo in the Nucleus Accumbens Suppresses Methamphetamine-Induced Hyperlocomotion and Conditioned Place Preference in Mice. Neurochem Res 47(9):2856-2864, 2022.<\/li>\n\n\n\n<li>Kutsuwada Y, Yokota K, Yoshida K, Tsuda H, Watanabe K, Matsumoto A, Iwamoto S.: Association of HLA-DPB1, NLRP10, OVOL1, and ABCC11 with the axillary microbiome in a Japanese population. Journal of dermatological science. 105(2):98-104, 2022<\/li>\n\n\n\n<li>Matsumoto A, Tsuda H, Furui S, Kawada-Nagashima M, Anzai T, Seki M, Watanabe K, Muramatsu K, Osaka H, Iwamoto S, Nishino I, Yamagata T.: A case of congenital fiber-type disproportion syndrome presenting dilated cardiomyopathy with ACTA1 mutation. Molecular genetics &amp; genomic medicine. 2022:e2008.<\/li>\n\n\n\n<li>Miyanishi H, Kitazawa A, Izuo N, Muramatsu S, Nitta A.: N-Acetyl Transferase, Shati\/Nat8l, in the Dorsal Hippocampus Suppresses Aging- induced Impairment of Cognitive Function in Mice. Neurochem Res 47(9):2703-2714, 2022.<\/li>\n\n\n\n<li>Muramatsu K, Muramatsu S.: Adeno-associated virus vector-based gene therapies for pediatric diseases. Pediatr Neonatol 64(1):S3-S9, 2022.<\/li>\n\n\n\n<li>Nishiyama C, Saito Y, Sakaguchi A, Kaneko M, Kiyonari H, Xu Y, Arima Y, Uosaki H, Kimura W.: Prolonged Myocardial Regenerative Capacity in Neonatal Opossum. Circulation. Jul 12;146(2):125-139, 2022.<\/li>\n\n\n\n<li>Reiss UM, Mahlangu J, Ohmori T, Ozalo MC, Srivastava A, Zhang L.: Hemophilia gene therapy \u2013 Update on New country initiatives. Haemophilia 28 Suppl 4: 61-67, 2022.<\/li>\n\n\n\n<li>Tai CH, Lee NC, Chien YH, Byrne BJ, Muramatsu S, Tseng SH, Hwu PW.: Long-term efficacy and safety of eladocageneexuparvovec in patients with AADC deficiency. Mol Ther 30(2):509-518, 2022.<\/li>\n\n\n\n<li>Tokuyama T, Uosaki H, Sugiura A, Nishitai G, Takeda K, Nagashima S, Shiiba I, Ito N, Amo T, Mohri S, Nishimura A, Nishida M, Konno A, Hirai H, Ishido S, Yoshizawa T, Shindo T, Takada S, Kinugawa S, Inatome R, Yanagi S.: Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience. Jun 11;25(7):104582, 2022.<\/li>\n\n\n\n<li>Tsukida K, Muramatsu S, Osaka H, Yamagata T, Muramatsu K.: WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction. Brain Commun 4(6): fcac304, 2022.<\/li>\n\n\n\n<li>Watanabe K, Matsumoto A, Tsuda H, Iwamoto S.: KBTBD11, encoding a novel PPAR\u03b3 target gene, is involved in NFATc1 proteolysis by interacting with HSC70 and HSP60. Scientific reports. 2022;12(1):20273.<\/li>\n\n\n\n<li>Yamane H, Seki M, Ikeda T, Matsumoto A, Furui S, Sato T, Muramatsu K, Tajima T, Yamagata T.: An Adolescent Patient with Sick Sinus Syndrome Complicated by Hypothyroidism Carrying an SCN5A Variant. International heart journal. 2022;63(3):627-32.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">B. \u5b66\u4f1a\u767a\u8868<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u5b89\u6e08\u9054\u4e5f,\u9b5a\u5d0e\u82f1\u6bc5,Chanthra Nawin,\u68ee\u7530\u88d5\u4ecb,\u798f\u4e95\u6c99\u7e54,\u53e4\u4e95\u8c9e\u6d69,\u9234\u6728\u5cfb, \u5ca1\u5065\u4ecb,\u6a2a\u6e9d\u4e9c\u5e0c\u5b50,\u677e\u539f\u5927\u8f14,\u677e\u672c\u6b69,\u4f50\u85e4\u667a\u5e78,\u95a2\u6e80,\u5c71\u5f62\u5d07\u502b:\u30de\u30a6\u30b9 ES \u7d30\u80de\u7531\u6765\u5fc3\u7b4b\u7d30\u80de\u3068\u30a2\u30c7\u30ce\u968f\u4f34\u30a6\u30a4\u30eb\u30b9\u3092\u7528\u3044\u305f\u62d8\u675f\u578b\u5fc3\u7b4b\u75c7\u306e\u75be\u60a3\u30e2\u30c7\u30ea\u30f3\u30b0. \u7b2c 58 \u56de\u65e5\u672c\u5c0f\u5150\u5faa\u74b0\u5668\u5b66\u4f1a, \u672d\u5e4c, 2022\/7\/23.<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u30ef\u30af\u30c1\u30f3\u958b\u767a\u30aa\u30fc\u30d0\u30fc\u30d3\u30e5\u30fc\uff0e\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u7b2c 7 \u56de\u81e8\u5e8a\u8a66\u9a13\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30b3\u30fc\u30b9\uff0c\u798f\u5ca1\uff0c2022 \u5e74 7 \u6708 16 \u65e5\uff0e<\/li>\n\n\n\n<li>\u677e\u672c\u6b69,\u6d25\u7530\u82f1\u5229,\u6c60\u7530\u5c1a\u5e83,\u5bae\u5185\u5f70\u5f66,\u6a4b\u53e3\u4e07\u91cc\u5948,\u9580\u7530\u884c\u53f2,\u8f61\u7530\u884c\u4fe1,\u6e21\u908a\u548c\u5bff,\u6751\u677e\u4e00\u6d0b,\u5c0f\u5742\u4ec1,\u5ca9\u672c\u798e\u5f66,\u5c71\u5f62\u5d07\u502b\uff1a\u96e3\u6cbb\u6027\u3066\u3093\u304b\u3093\u3001\u5149\u3001\u97f3\u904e\u654f\u3092\u5448\u3057\u305f DNM1L \u5909\u7570\u306e 1 \u6b73\u7537\u5150\u4f8b.\u4eba\u985e\u907a\u4f1d\u5b66\u4f1a\u7b2c 67 \u56de\u5927\u4f1a,\u30d1\u30b7\u30d5\u30a3\u30b3\u6a2a\u6d5c,2022 \u5e7410 \u6708 14 \u65e5-17.(\u4eba\u985e\u907a\u4f1d\u5b66\u4f1a\u6284\u9332\u96c6:p159, 2022\uff09<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV \u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6cbb\u7642 update.\u30e9\u30f3\u30c1\u30e7\u30f3\u30bb\u30df\u30ca\u30fc14 \u810a\u9ac4\u6027\u7b4b\u840e\u7e2e\u75c7(SMA)\u306e\u907a\u4f1d\u5b50\u6cbb\u7642,\u7b2c 64 \u56de\u65e5\u672c\u5c0f\u5150\u795e\u7d4c\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u7fa4\u99ac, 2022 \u5e74 6 \u6708 4 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p S47)<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV \u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\uff1a\u73fe\u72b6\u3068\u8ab2\u984c.\uff0d\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 12 \u30a2\u30c7\u30ce\u968f\u4f34\u30a6\u30a4\u30eb\u30b9(AAV)\u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305f\u795e\u7d4c\u75be\u60a3\u306e\u5275\u85ac\u7814\u7a76\u30fb\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u52d5\u5411\uff0d.\u7b2c 96 \u56de\u65e5\u672c\u85ac\u7406\u5b66\u4f1a\u5e74\u4f1a,\u6a2a\u6d5c,2022 \u5e74 11 \u6708 30 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p95)<\/li>\n\n\n\n<li>Munkh-Erdene Natsagdorj, Hiromasa Hara, Suvd Byambaa, Fumio Nakahara, Yasumitsu Nagao, Hideki Uosaki, Yutaka Hanazono: Development of a New Immunodeficient Mouse Strain Capable of Pig Cell Engraftment, \u7b2c 8 \u56de\u65e5\u672c\u5148\u9032\u533b\u5de5\u5b66\u30d6\u30bf\u7814\u7a76\u4f1a\u7814\u7a76\u96c6\u4f1a,\u795e\u5948\u5ddd,2022\/10\/21.<\/li>\n\n\n\n<li>Nawin Chanthra, Razan E. Ahmed, Tatsuya Anzai, Takeshi Tokuyama, Yutaka Hanazono, Hideki Uosaki: Nuclear Receptors Coordinately Regulate Cardiomyocyte Maturation, \u7b2c 86 \u56de\u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a, \u30aa\u30f3\u30e9\u30a4\u30f3\u958b\u50ac, 2022\/3\/11.<\/li>\n\n\n\n<li>Nawin Chanthra, Razan E. Ahmed, Tatsuya Anzai, Takeshi Tokuyama, Kumiko A. Iwabuchi, Yutaka Hanazono, Hideki Uosaki: Hormone and nuclear receptor activations are required for cardiomyocyte maturation. XXIV World Congress International Society for Heart Research, Berlin, Germany, 2022\/6\/15.<\/li>\n\n\n\n<li>\u5927\u8cab\u826f\u5e78,\u5c0f\u91ce\u3055\u3084\u304b,\u5c0f\u5cf6\u83ef\u6797,\u591a\u8cc0\u76f4\u884c,\u6c60\u7530\u5c1a\u5e83,\u9ed2\u5ddd\u611b\u6075,\u5bae\u5185\u5f70\u5f66,\u4f50\u85e4\u4fe1,\u5927\u8c37\u5553\u4ecb,\u5ddd\u5408\u5065\u4ecb,\u5c0f\u5742\u4ec1,\u4f50\u85e4\u4fca\u5f66,\u6751\u677e\u614e\u4e00,\u5c71\u5f62\u5d07\u502b,\u4e2d\u5d8b\u525b\uff1aAADC \u907a\u4f1d\u5b50\u6cbb\u7642\u306b\u3088\u308b\u5927\u8133\u57fa\u5e95\u6838\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u6a5f\u80fd\u56de\u5fa9.\u7b2c 61 \u56de\u65e5\u672c\u5b9a\u4f4d\u30fb\u6a5f\u80fd\u795e\u7d4c\u5916\u79d1\u5b66\u4f1a,\u5927\u962a,2022 \u5e74 1 \u6708 29 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p72)<\/li>\n\n\n\n<li>Razan E Ahmed, Nawin Chanthra, Kumiko A Iwabuchi, Takeshi Tokuyama, Hideki Uosaki: Disease Modeling of Mitochondrial Cardiomyopathy Using Patient-Derived Induced Pluripotent Stem Cells. ISHR\/CVMW, Tokyo, Japan, 2022\/12\/17.<\/li>\n\n\n\n<li>Suvd Byambaa, Hideki Uosaki, Hiromasa Hara, Munkh-Erdene Natsagdorj, Tsukasa Ohmori, Satoshi Yamazaki, Yutaka Hanazono: Targeted genome repair in selectively expanded mouse long-term hematopoietic stem cells, \u7b2c 28 \u56de\u65e5\u672c\u907a\u4f1d\u5b50\u7d30\u80de\u6cbb\u7642\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a,\u798f\u5ca1,2022\/7\/16.<\/li>\n\n\n\n<li>Suvd Byambaa, Hideki Uosaki, Hiromasa Hara, Munkh-Erdene Natsagdorj, Tsukasa Ohmori, Satoshi Yamazaki, Yutaka Hanazono: Targeted genome repair in selectively expanded mouse long-term hematopoietic stem cells, The 45th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2022),\u5343\u8449,2022\/12\/1.<\/li>\n\n\n\n<li>\u5fb3\u5c71\u525b\u58eb\uff1a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u5916\u819c\u4e0a\u306e\u6383\u9664\u6a5f\u69cb\u306e\u7834\u7dbb\u304c\u5fc3\u7b4b\u6897\u585e\u306e\u75c5\u614b\u3092\u60aa\u5316\u3055\u305b\u308b. \u7b2c 51 \u56de\u5fc3\u8108\u7ba1\u4f5c\u52d5\u7269\u8cea\u5b66\u4f1a, \u6771\u4eac, 2022\/7\/31.<\/li>\n\n\n\n<li>\u5fb3\u5c71\u525b\u58eb\u3001\u9b5a\u5d0e\u82f1\u6bc5\u3001\u67f3\u8302\uff1a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u9175\u7d20 MITOL \u306e\u4f4e\u4e0b\u306f\u5fc3\u81d3\u8001\u5316\u3084\u5fc3\u7b4b\u6897\u585e\u3092\u5897\u60aa\u3057\u3001MITOL \u306e\u6d3b\u6027\u5316\u306f\u5fc3\u7b4b\u6897\u585e\u306e\u91cd\u75c7\u5316\u3092\u6291\u5236\u3059\u308b. \u7b2c 45 \u56de\u65e5\u672c\u5206\u5b50\u751f\u7269\u5b66\u4f1a\u5e74\u4f1a, \u5343\u8449, 2022\/12\/2.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u5faa\u74b0\u5668\u57fa\u790e\u7814\u7a76\u306e\u547c\u3073\u58f0. \u7b2c 263 \u56de \u65e5\u672c\u5faa\u74b0\u5668\u5b66\u4f1a \u95a2\u6771\u7532\u4fe1\u8d8a\u5730\u65b9\u4f1a\uff08\u6559\u80b2\u8b1b\u6f14\uff09, \u30aa\u30f3\u30e9\u30a4\u30f3\u958b\u50ac, 2022\/2\/26.<\/li>\n\n\n\n<li>Hideki Uosaki: Recapturing Cardiomyopathy with Induced Pluripotent Stem Cells, MIS-Korea 2022, Seoul, \u97d3\u56fd\/\u30aa\u30f3\u30e9\u30a4\u30f3, 2022\/3\/3.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u7528\u3044\u305f\u5148\u5929\u6027\u75be\u60a3\u30e2\u30c7\u30eb\u52d5\u7269\u306e\u4f5c\u51fa\u3068\u89e3\u6790. \u7b2c 62 \u56de\u65e5\u672c\u5148\u5929\u7570\u5e38\u5b66\u4f1a, \u91d1\u6ca2, 2022\/7\/30.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u5fc3\u7b4b\u75c7\u7814\u7a76\u306e\u305f\u3081\u306e iPS \u7d30\u80de\u30e2\u30c7\u30eb. \u7b2c 70 \u56de \u65e5\u672c\u5fc3\u81d3\u75c5\u5b66\u4f1a, \u4eac\u90fd, 2022\/9\/24.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u30e1\u30ab\u30cb\u30ba\u30e0\u89e3\u660e\u306b\u5411\u3051\u305f\u6311\u6226. \u7b2c 21 \u56de\u65e5\u672c\u5fc3\u81d3\u8840\u7ba1\u767a\u751f\u7814\u7a76, \u6771\u4eac, 2022\/12\/18.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">C. \u8457\u66f8\u30fb\u7dcf\u8aac<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Ahmed RE, Tokuyama T, Anzai T, Chanthra N, Uosaki H: Sarcomere maturation: functional acquisition, molecular mechanism, and interplay with other organelles. Philos Trans R Soc Lond B Biol Sci. Nov 21;377(1864):20210325, 2022.<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u308f\u304c\u56fd\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642\u30fb\u907a\u4f1d\u5b50\u6cbb\u7642\u88fd\u54c1\u306e\u958b\u767a\uff0e\u816b\u760d\u5185\u79d1 29(4):518-522, 2022\uff0e<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u30d7\u30e9\u30b9\u30df\u30c9 DNA \u306e CMC \u306b\u95a2\u308f\u308b\u898f\u5236\u8981\u4ef6\u3068\u5bfe\u5fdc\uff0ePharmstage 22(3): 42-48, 2022\uff0e<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aParkinson \u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642.\u8133\u795e\u7d4c\u5185\u79d1 96(2):196-199, 2022.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u3066\u3093\u304b\u3093\u306e\u907a\u4f1d\u5b50\u6cbb\u7642. \u3066\u3093\u304b\u3093\u306e\u7dcf\u5408\u5b66\u8853\u8a8c Epilepsy 16(1):37-41, 2022.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u795e\u7d4c\u75be\u60a3\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\uff0dAAV \u30d9\u30af\u30bf\u30fc\u306e\u5b89\u5168\u6027.\u7279\u96c6&nbsp; \u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u6700\u524d\u7dda. Medical Science Digest 48(13):14-17(630-633), 2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:\u3010\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u6700\u524d\u7dda\u3011\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b AAV \u30d9\u30af\u30bf\u30fc\u907a\u4f1d\u5b50\u6cbb\u7642. Medical Science Digest(1347-4340): 48(13): 634-638\uff0c2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:\u30c8\u30d4\u30c3\u30af\u30b9\uff1a\u8840\u6db2\u75be\u60a3\u306b\u5bfe\u3059\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642. In: \u91d1\u5009\u8b72\uff0c\u6728\u5d0e\u660c\u5b8f\uff0c\u9234\u6728\u5f8b\u6717\uff0c\u795e\u7530\u5584\u4f38\uff0c\u5927\u68ee\u53f8\uff0c\u5c71\u5d0e\u5b8f\u4eba(\u7de8)\uff0cEBM \u8840\u6db2\u75be\u60a3\u306e\u6cbb\u7642 2023- 2024\uff0c\u4e2d\u5916\u533b\u5b66\u793e\uff0c69-71\uff0c2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:\u8840\u5c0f\u677f\u30fb\u51dd\u56fa\u306e\u5f79\u5272. <em>In<\/em>: \u795e\u7530\u5584\u4f38(\u7de8)\uff0c\u3053\u3053\u304c\u77e5\u308a\u305f\u3044\uff01\u8840\u6db2\u75be\u60a3\u8a3a\u7642\u30cf\u30f3\u30c9\u30d6\u30c3\u30af\uff0c\u4e2d\u5916\u533b\u5b66\u793e\uff0c17-24\uff0c2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:DIC. <em>In<\/em>: \u9580\u8107\u5b5d\uff0c\u5c0f\u5ba4\u4e00\u6210\uff0c\u5bae\u5730\u826f\u6a39(\u7de8)\uff0c\u65e5\u5e38\u8a3a\u7642\u306b\u6d3b\u304b\u3059\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3&nbsp;&nbsp; UP-TO-DATE2022-2023\uff0c\u30e1\u30c7\u30a3\u30ab\u30eb\u30d3\u30e5\u30fc\u793e\uff0c510-514\uff0c2022\uff0e<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:von Willebrand \u75c5. <em>In<\/em>: \u677e\u6751\u5230\uff0c\u5f35\u66ff\u79c0\u90ce\uff0c\u795e\u7530\u5584\u4f38(\u7de8)\uff0c\u8840\u6db2\u75be\u60a3\u6700\u65b0\u306e\u6cbb\u7642 2023-2025\uff0c\u5357\u6c5f\u5802\uff0c218-221\uff0c2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:\u30b2\u30ce\u30e0\u7de8\u96c6\u306b\u3088\u308b\u6cbb\u7642\u306e\u5b9f\u969b.&nbsp;&nbsp; <em>In<\/em>:\u5c71\u672c\u5353\uff0c\u30b2\u30ce\u30e0\u7de8\u96c6\u3068\u533b\u7642\uff0c\u88f3\u83ef\u623f\uff0c90-134\uff0c2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u30fb\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642.\u65e5\u672c\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u5b66\u4f1a\u8a8c: 43(4): 245-252\uff0c2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8:\u3010\u77e5\u3063\u3066\u304a\u304d\u305f\u3044\u8840\u6813\u4e88\u9632\u7642\u6cd5\u306e\u30a8\u30c3\u30bb\u30f3\u30b9\u3011\u8840\u6813\u5f62\u6210\u306e\u75c5\u614b\u751f\u7406\u3068\u6297\u8840\u6813\u85ac \u52d5\u8108\u8840\u6813\u3068\u9759\u8108\u8840\u6813(\u89e3\u8aac).\u8a3a\u65ad\u3068\u6cbb\u7642(0370-999X): 110(4): 409-413\uff0c2022.<\/li>\n\n\n\n<li>\u5fb3\u5c71\u525b\u58eb\u3001\u5b89\u6e08\u9054\u4e5f\u3001\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u75c5\u306e iPS \u7d30\u80de\u3092\u7528\u3044\u305f\u75c5\u614b\u89e3\u660e,&nbsp; \u5c0f\u5150\u5185\u79d1\u300c\u75c7\u4f8b\u304b\u3089\u5b66\u3076\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u75c5\u300d, Apr 20; 54(4):635-639, 2022.<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb,\u5927\u5dba\u8b19:AML \u306b\u5bfe\u3059\u308b CAR-T \u7642\u6cd5\u306e\u958b\u767a\u306e\u73fe\u72b6\u3068\u65b0\u898f CD70 \u7279\u7570\u7684CAR-T.\u8840\u6db2\u5185\u79d1.2022;84:730-6.<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb,\u5927\u5dba\u8b19:CAR-T \u7d30\u80de\u7642\u6cd5\u306e\u73fe\u72b6\u3068\u8ab2\u984c.Bio clinica.2022;37:525-9.<\/li>\n\n\n\n<li>\u5185\u5800\u4eae\u4ecb,\u5c0f\u6fa4\u656c\u4e5f:VISUAL&amp;LECTURE: CAR-T \u7d30\u80de\u7642\u6cd5\u3068\u304c\u3093\u514d\u75ab\u7642\u6cd5.\u304c\u3093\u514d\u75ab\u7642\u6cd5.2022;4:4-8.<\/li>\n\n\n\n<li>Ohmine, K., Uchibori, R.: Novel immunotherapies in multiple myeloma. Int J Hematol. 2022;115:799-810.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">D. \u7279\u8a31<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u540d\u79f0:\u30c6\u30a4\uff0d\u30b5\u30c3\u30af\u30b9\u75c5\u53ca\u3073\u30b6\u30f3\u30c9\u30db\u30c3\u30d5\u75c5\u6cbb\u7642\u7528\u306e\u65b0\u898f\u30a2\u30c7\u30ce\u968f\u4f34\u30a6\u30a4\u30eb\u30b9\u30d3\u30ea\u30aa\u30f3<br>\u767a\u660e\u8005\uff1a\u4f0a\u85e4\u5b5d\u53f8\u3001\u8fbb\u5927\u8f14\u3001\u6751\u677e\u614e\u4e00\u3001\u6d45\u4e95\u514b\u4ec1<br>\u51fa\u9858\u8005\uff1a\u5fb3\u5cf6\u5927\u5b66\u3001\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u3001(\u682a)\u907a\u4f1d\u5b50\u6cbb\u7642\u7814\u7a76\u6240\u756a\u53f7\u3000: \u7279\u8a31 2018\uff0d011705<br>\u51fa\u9858\u5e74\u6708\u65e5: 2022 \u5e74 9 \u6708 2 \u65e5\u767b\u9332<\/li>\n\n\n\n<li>\u540d\u79f0:\u907a\u4f1d\u5b50\u6539\u5909\u514d\u75ab\u7d30\u80de\u7642\u6cd5\u306e\u305f\u3081\u306e\u9078\u629e\u7684\u5236\u5fa1\u907a\u4f1d\u5b50(SRG)\u30b7\u30b9\u30c6\u30e0<br>\u767a\u660e\u8005\uff1a\u5185\u5800\u4eae\u4ecb\u3001\u5927\u5dba\u8b19\u3001\u5c0f\u6fa4\u656c\u4e5f<br>\u756a\u53f7\u3000:\u7279\u9858 2022-052759<br>\u51fa\u9858\u5e74\u6708\u65e5:2022 \u5e74 3 \u6708 29 \u65e5\u51fa\u9858<\/li>\n<\/ol>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">E. \u305d\u306e\u4ed6<\/h5>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u82b1\u5712\u8c4a,\u539f\u5f18\u771f,\u30b9\u30d6\u30c9\u30fb\u30d3\u30e3\u30f3\u30d0\u30fc,\u8c37\u539f\u53f2\u502b\uff1a\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642\u306b\u304a\u3051\u308b\u30d4 \u30c3\u30b0\u30e2\u30c7\u30eb\u306e\u6709\u7528\u6027\u3068\u81ea\u6cbb\u533b\u5927\u30d4\u30c3\u30b0\u30bb\u30f3\u30bf\u30fc\u306e\u5f79\u5272.\u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 2022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p32-33)<\/li>\n\n\n\n<li>\u4e45\u7c73\u6643\u5553\uff1a\u518d\u751f\u533b\u7642\u7b49\u88fd\u54c1\uff1a\u65b0\u30ab\u30c6\u30b4\u30ea\u30fc\u5be9\u67fb\u306e 7 \u5e74\u3092\u632f\u308a\u8fd4\u308b.\u7b2c 4 \u56de JMU- CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 2022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p34-35)<\/li>\n\n\n\n<li>\u6c34\u4e0a\u6d69\u660e,\u7dbf\u91ce\u4eae\u592a,\u5927\u5ead\u8ce2\u4e8c,\u702c\u539f\u5409\u82f1,\u5d6f\u5ce8\u6cf0,\u535c\u90e8\u5321\u53f8\uff1aAAV \u30d9\u30af\u30bf\u30fc\u3068\u514d\u75ab\u53cd\u5fdc.\u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 2022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p26-27)<\/li>\n\n\n\n<li>Munkh-Erdene Natsagdorj, Hiromasa Hara, Suvd Byambaa, Fumio Nakahara, Yasumitsu Nagao, Hideki Uosaki, Yutaka Hanazono: Increasing the AAV- mediated HDR efficiencies in hematopoietic cells. 20th JMU symposium, \u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0(20th JMU symposium), \u6803\u6728, 2022\/9\/8.<\/li>\n\n\n\n<li>Munkh-Erdene Natsagdorj, Hiromasa Hara, Suvd Byambaa, Fumio Nakahara, Yasumitsu Nagao, Hideki Uosaki, Yutaka Hanazono: Development of a New Immunodeficient Mouse Strain Capable of Pig Cell Engraftment, \u81ea\u6cbb\u533b\u79d1\u5927\u5b66&nbsp; \u7b2c 7 \u56de\u5927\u5b66\u9662\u751f\u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7, \u6803\u6728, 2022\/11\/9.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u3053\u308c\u304b\u3089\u306f\u3058\u307e\u308b\u6cbb\u9a13\uff1aPD \u3068 ALS.\u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e02022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p22-23)<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u60a3\u8005\u304c\u77e5\u308a\u305f\u3044\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u4eca\u3068\u3053\u308c\u304b\u3089.\u5168\u56fd\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u53cb\u306e\u4f1a \u795e\u5948\u5ddd\u770c\u652f\u90e8 \u7b2c 47 \u56de\u5b9a\u671f\u7dcf\u4f1a\u8a18\u5ff5\u533b\u7642\u8b1b\u6f14\u4f1a,\u6a2a\u6d5c\u5e02,2022 \u5e74 6 \u6708 4 \u65e5.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642.\u5168\u56fd\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u53cb\u306e\u4f1a \u6803\u6728\u770c\u652f\u90e8 \u7b2c 1 \u56de\u533b\u7642\u8b1b\u6f14\u4f1a,Web \u958b\u50ac,2022 \u5e74 6 \u6708 18 \u65e5.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u795e\u7d4c\u75be\u60a3\u306e\u6f22\u65b9\u6cbb\u7642.\u7b2c 52 \u56de KAMPO SEMINAR in \u6ecb\u8cc0\u533b\u5927,Web \u958b\u50ac, 2022 \u5e74 9 \u6708 1 \u65e5.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u79c1\u306e\u983b\u7528\u51e6\u65b9\uff0d\u795e\u7d4c\u75be\u60a3\u3092\u4e2d\u5fc3\u306b\uff0d.\u7b2c 28 \u56de\u65e5\u672c\u6771\u6d0b\u533b\u5b66\u4f1a\u95a2\u6771\u7532\u4fe1\u8d8a\u652f\u90e8 \u65b0\u6f5f\u770c\u90e8\u4f1a\u7dcf\u4f1a\u30fb\u8b1b\u6f14\u4f1a \u7279\u5225\u8b1b\u6f14,Web \u958b\u50ac,2022 \u5e74 9 \u6708 4 \u65e5.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1aAAV \u30d9\u30af\u30bf\u30fc\u306b\u3088\u308b\u907a\u4f1d\u5b50\u6cbb\u7642.\u7b2c\uff17\u56de\u4e09\u91cd\u770c\u5c0f\u5150\u795e\u7d4c\u61c7\u8a71\u4f1a,\u4e09\u91cd\u770c,2022 \u5e74 11 \u6708 10 \u65e5.<\/li>\n\n\n\n<li>\u6751\u677e\u614e\u4e00\uff1a\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u73fe\u72b6\u3068\u4eca\u5f8c\u306e\u5c55\u671b.\u6771\u96e3\u9023\u5275\u7acb 50 \u5468\u5e74\u30fb\u6cd5\u4eba\u5316 20 \u5468\u5e74\u8a18\u5ff5\u8b1b\u6f14\u4f1a,\u6771\u4eac,2022 \u5e74 12 \u6708 11 \u65e5.<\/li>\n\n\n\n<li>\u5927\u5dba\u8b19\uff1a\u5b9f\u81e8\u5e8a\u306b\u304a\u3051\u308b CAR-T \u7642\u6cd5\u306e\u8ab2\u984c.\u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e02022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p12-13)<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8,\u51a8\u6a2b\u670b\u8cb4,\u5e73\u672c\u8cb4\u53f2,Nemekhbayar Baatartsogt,\u65e9\u5ddd\u76db\u798e,\u67cf\u5009\u88d5\u5fd7, \u9d28\u4e0b\u4fe1\u5f66,\u7a32\u8449\u6d69,\u68ee\u4e0b\u82f1\u7406\u5b50,\u6fe1\u6728\u7406\uff1aAAV \u30d9\u30af\u30bf\u30fc\u3092\u7528\u3044\u305f in vivo \u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642.\u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 2022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0p30-31)<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u6210\u4eba\u60a3\u8005\u3055\u3093\u306e QOL \u7dad\u6301\u3068\u672a\u6765\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066.\u7fa4\u99ac\u770c\u8840\u53cb\u75c5\u30bb\u30df\u30ca\u30fc\uff0cWeb\uff0c2022 \u5e74 3 \u6708 6 \u65e5.<\/li>\n\n\n\n<li>Tsukasa Ohmori: Gene Therapy in Japan. WFH (World Federation of Haemophilia)2022 WORLD CONGRESS (Symposium), Toronto, Mar. 10, 2022.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642.\u7b2c 31\u30fb32 \u56de\u751f\u7269\u8a66\u6599\u5206\u6790\u79d1\u5b66\u4f1a&nbsp;&nbsp; \u5408\u540c\u5e74\u6b21\u5b66\u8853\u96c6\u4f1a\uff0cWeb\uff0c2022 \u5e74 3 \u6708 13 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u73fe\u72b6\u3068\u5c55\u671b.\u7b2c 117 \u56de\u57fc\u7389\u770c\u5c0f\u5150\u8840\u6db2\u540c\u597d\u4f1a\uff0cWeb\uff0c2022 \u5e74 4 \u6708 21 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u6cbb\u7642\u306e\u3053\u308c\u307e\u3067\u3068\u3053\u308c\u304b\u3089. Hemophilia Meeting in Tokyo\uff0c Web\uff0c2022 \u5e74 5 \u6708 19 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u7b2c VIII \u56e0\u5b50\u306e\u6a5f\u80fd\u89e3\u660e\u306b\u3088\u308b\u65b0\u305f\u306a\u8840\u53cb\u75c5\u6cbb\u7642\u3078\u306e\u5c55\u958b. \u4e2d\u5916 Thrombosis Hemostasis Research Seminar 2022\uff0c\u6771\u4eac\uff0c2022 \u5e74 5 \u6708 23 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u57fa\u790e\u7814\u7a76\u304b\u3089\u8003\u3048\u308b\u672a\u6765\u306e\u8840\u53cb\u75c5\u6cbb\u7642.\u5927\u962a\u8840\u53cb\u75c5\u5b66\u8853\u8b1b\u6f14\u4f1a\uff0c\u5927\u962a\uff0c2022 \u5e74 6 \u6708 4 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u30fb\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642.\u7b2c 46 \u56de\u65e5\u672c\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u5b66\u4f1a\uff0c\u6771\u4eac\uff0c2022 \u5e74 7 \u6708 3 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u304b\u3089\u307f\u305f\u30d5\u30a9\u30f3\u30f4\u30a3\u30ec\u30d6\u30e9\u30f3\u30c9\u75c5\u306e\u75c5\u614b\u3068\u8a3a\u65ad.\u5f8c\u5929\u6027\u8840\u53cb\u75c5 A\u30fb\u30d5\u30a9\u30f3\u30f4\u30a3\u30ec\u30d6\u30e9\u30f3\u30c9\u75c5 WEB \u8b1b\u6f14\u4f1a\uff0cWeb\uff0c2022 \u5e74 7 \u6708 11 \u65e5.<\/li>\n\n\n\n<li>Tsukasa Ohmori: The Potential of Genome Editing Treatment with an Engineered Cas. The 28th Annual Meeting of Japan Society of Gene and Cell Therapy, \u798f\u5ca1, 2022 \u5e74 7 \u6708 14 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u6cbb\u7642\u306e\u6b74\u53f2\u3068\u672a\u6765.\u306f\u3070\u305f\u304d\u798f\u7949\u4e8b\u696d\u56e3\u4e3b\u50ac\u30aa\u30f3\u30e9\u30a4\u30f3\u30bb\u30df\u30ca \u30fc\u907a\u4f1d\u5b50\u306e\u57fa\u672c\u77e5\u8b58\u3068\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u73fe\u72b6\u3092\u7406\u89e3\u3057\u3088\u3046\uff0cWeb\uff0c2022 \u5e74 7 \u6708 23 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u51dd\u56fa\u56e0\u5b50\u6a5f\u80fd\u306e\u89e3\u660e\u3092\u57fa\u76e4\u3068\u3057\u305f\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b\u6b21\u4e16\u4ee3\u6cbb\u7642\u6cd5\u306e\u958b\u767a.\u7b2c 16 \u56de\u962a\u795e\u30d8\u30e2\u30d5\u30a3\u30ea\u30a2\u7814\u7a76\u4f1a\uff0cWeb\uff0c2022 \u5e74 7 \u6708 30 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u3092\u7528\u3044\u305f\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u73fe\u72b6\u3068\u5c55\u671b.\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c 7 \u56de\u5e74\u4f1a\uff0c\u6771\u4eac\uff0c2022 \u5e74 8 \u6708 1 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642.\u7b2c 3 \u56de\u8840\u6db2\u57fa\u790e Web \u30bb\u30df\u30ca\u30fc in Kanagawa\uff0cWeb\uff0c2022 \u5e74 9 \u6708 6 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u57fa\u790e\u7814\u7a76\u304b\u3089\u8003\u3048\u308b\u672a\u6765\u306e\u8840\u53cb\u75c5\u6cbb\u7642.\u3064\u304f\u3070\u8840\u53cb\u75c5\u30d5\u30a9\u30fc\u30e9\u30e02022\uff0cWeb\uff0c2022 \u5e74 9 \u6708 15 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u57fa\u790e\u7814\u7a76\u304b\u3089\u8003\u3048\u308b\u672a\u6765\u306e\u8840\u53cb\u75c5\u6cbb\u7642.\u7b2c 17 \u56de\u9e7f\u5150\u5cf6\u30d8\u30e2\u30d5\u30a3\u30ea\u30a2\u30ab\u30f3\u30d5\u30a1\u30e9\u30f3\u30b9\uff0cWeb\uff0c2022 \u5e74 9 \u6708 15 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u6cbb\u7642\u306e\u3053\u308c\u307e\u3067\u3068\u3053\u308c\u304b\u3089.\u306f\u3058\u3081\u3066\u306e\u8840\u53cb\u75c5\u8a3a\u7642\uff0cWeb\uff0c2022\u5e74 9 \u6708 22 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642.\u7b2c 62 \u56de\u65e5\u672c\u81e8\u5e8a\u5316\u5b66\u4f1a\u5e74\u6b21\u5b66\u8853\u96c6\u4f1a\uff0c\u5bcc\u5c71\uff0c2022 \u5e74 9 \u6708 30 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5 B \u306e\u75c5\u614b\u3068\u8a3a\u65ad.Alprolix Webinar \u8840\u53cb\u75c5 B \u6700\u65b0\u306e\u77e5\u898b\uff0c Web\uff0c2022 \u5e74 11 \u6708 29 \u65e5.<\/li>\n\n\n\n<li>\u5927\u68ee\u53f8\uff1a\u8840\u53cb\u75c5\u306e\u75c5\u614b\u3068\u6cbb\u7642.\u7b2c 10 \u56de\u85ac\u5e2b\u5bfa\u9020\u8840\u5668\u816b\u760d\u30bb\u30df\u30ca\u30fc\uff0cWeb\uff0c2022 \u5e74 12 \u6708 14 \u65e5.<\/li>\n\n\n\n<li>\u5c0f\u5742\u4ec1,\u4e2d\u6751\u5e78\u6075,\u9ed2\u5ddd\u611b\u6075,\u5c0f\u5cf6\u83ef\u6797,\u6e21\u9089\u77e5\u4f73,\u5bae\u5185\u5f70\u5f66,\u795e\u4fdd\u6075\u7406\u5b50,\u4e2d\u5d8b\u525b,\u6751\u677e\u614e\u4e00,\u6751\u677e\u4e00\u6d0b,\u5c71\u5f62\u5d07\u502b\uff1a\u5c0f\u5150\u907a\u4f1d\u6027\u795e\u7d4c\u75be\u60a3\u306b\u5bfe\u3059\u308b AAV \u907a\u4f1d\u5b50\u6cbb\u7642 \uff5e\u81ea\u6cbb\u533b\u5927\u3067\u306e\u958b\u767a\u72b6\u6cc1\uff5e \u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 2022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p24-25)<\/li>\n\n\n\n<li>Suvd Byambaa, Hideki Uosaki, Hiromasa Hara, Munkh-Erdene Natsagdorj, Fumio Nakahara, Yutaka Hanazono: Targeted genome repair in expanded mouse long-term hematopoietic stem cells. \u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0(20th JMU symposium), \u6803\u6728, 2022\/9\/8.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1aiPS \u7d30\u80de\u3092\u5229\u7528\u3057\u305f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u5fc3\u7b4b\u75c7\u7814\u7a76. \u7b2c 6 \u56de\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u75c5\u7814\u7a76\u30d5\u30a9\u30fc\u30e9\u30e0, \u30aa\u30f3\u30e9\u30a4\u30f3, 2022\/2\/5.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u30e1\u30ab\u30cb\u30ba\u30e0\u7814\u7a76\u3068\u5fc3\u7b4b\u75c7\u7814\u7a76\u3078\u306e\u5fdc\u7528, \u5faa\u74b0\u5668Expert Web Seminar, \u30aa\u30f3\u30e9\u30a4\u30f3, 2022\/5\/24.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1aiPS \u7d30\u80de\u3092\u7528\u3044\u305f\u5fc3\u7b4b\u75c7\u306e\u75be\u60a3\u30e2\u30c7\u30eb, \u91d1\u6ca2\u533b\u79d1\u5927\u5b66 \u533b\u5b66\u7814\u7a76\u30bb\u30df\u30ca\u30fc, \u91d1\u6ca2, 2022\/6\/17.<\/li>\n\n\n\n<li>\u9b5a\u5d0e\u82f1\u6bc5\uff1a\u5fc3\u7b4b\u7d30\u80de\u306e\u6210\u719f\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd. \u30a2\u30b8\u30ec\u30f3\u30c8\u7d30\u80de\u89e3\u6790\u30bb\u30df\u30ca\u30fc, \u30aa\u30f3\u30e9\u30a4\u30f3, 2022\/12\/21.<\/li>\n\n\n\n<li>Hideki Uosaki\uff1aCardiomyocyte Maturation and Disease Modeling using iPS cells, Interstellar Initiative Alumni Symposium, \u30aa\u30f3\u30e9\u30a4\u30f3, 2023\/2\/7.<\/li>\n\n\n\n<li>\u535c\u90e8\u5321\u53f8\uff1aAAV \u30d9\u30af\u30bf\u30fc\u306e\u4f5c\u88fd\u6280\u8853.\u7b2c 4 \u56de JMU-CGTR \u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 2022,\u4e0b\u91ce,2022 \u5e74 2 \u6708 3 \u65e5.(\u30d7\u30ed\u30b0\u30e9\u30e0 p18-19)<\/li>\n<\/ol>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">2021\u5e74<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">Q&amp;A<\/h3>\n\n\n\n<div class=\"wp-block-group accordion\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group accordion_ttl\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading\">\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7\u3000\u5f53\u65e5\u8cea\u554f<\/h4>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion_wrap\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-table is-style-regular\"><table><thead><tr><th class=\"has-text-align-left\" data-align=\"left\">\u8cea\u554f<\/th><th class=\"has-text-align-left\" data-align=\"left\">\u56de\u7b54<\/th><\/tr><\/thead><tbody><tr><td class=\"has-text-align-left\" data-align=\"left\">AAV\u306f\u5168\u3066\u306e\u4eba\u306b\u4f7f\u3046\u3053\u3068\u304c\u3067\u304d\u305a\u3001<br>AAV\u306b\u5bfe\u3059\u308b\u4e2d\u548c\u6297\u4f53\u3092\u6301\u3063\u3066\u3044\u308b\u4eba\u304c<br>\u4eba\u53e3\u306e\u534a\u5206\u4ee5\u4e0a\u3082\u3044\u308b\u3068\u52b9\u304d\u307e\u3057\u305f\u3002<br>\u305d\u3046\u3057\u305f\u65b9\u3005\u306b\u5411\u3051\u3066\u306eAAV\u7642\u6cd5\u306f<br>\u3069\u306e\u3088\u3046\u306b\u958b\u767a\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u79c1\u9054\u306f\u3001\u904e\u53bb\u306b\u56fd\u5185\u306e\u8840\u53cb\u75c5\u60a3\u8005\u3055\u3093\u3084\u5065\u5e38\u4eba\u306e\u4e2d\u548c\u6297\u4f53\u306e\u4fdd\u6709\u7387\u3092<br>300\u540d\u3092\u8d85\u3048\u308b\u4eba\u3067\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002<br>\u69d8\u3005\u306aAAV\u8840\u6e05\u578b\uff08\u7a2e\u985e\uff09\u3067\u6982\u306d20~30%\u3067\u3059\u3002<br>60\u6b73\u4ee5\u4e0a\u3067\u4fdd\u6709\u7387\u304c\u9ad8\u304f\u3001\u82e5\u5e74\u5c64\u3067\u306f20%\u7a0b\u5ea6\u3067\u3059\u3002<br>AAV\u30d9\u30af\u30bf\u30fc\u3092\u6295\u4e0e\u5f8c\u306fAAV\u306b\u5bfe\u3059\u308b\u6297\u4f53\u304c\u3067\u304d\u3066\u3057\u307e\u3046\u306e\u3067\u3001\u9759\u8108\u6295\u4e0e\u306f<br>2\u56de\u76ee\u306e\u6295\u4e0e\u304c\u3067\u304d\u306a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\u4e2d\u548c\u6297\u4f53\u3092\u6301\u3064\u65b9\u3001\u304a\u3088\u3073\u518d\u6295\u4e0e\u306b\u3064\u3044\u3066\u306f\u73fe\u5728\u3001\u591a\u304f\u306e\u7814\u7a76\u8005\u304c\u7814\u7a76\u3092<br>\u63a8\u9032\u3057\u3066\u3044\u307e\u3059\uff08\u5927\u68ee\uff09\u3002<br>\u8133\u3078\u306e\u76f4\u63a5\u6295\u4e0e\u3067\u306f\u4e2d\u548c\u6297\u4f53\u3092\u6301\u3063\u3066\u3044\u308b\u4eba\u3067\u3082\u6cbb\u7642\u53ef\u80fd\u3067\u3059\u3002<br>\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">AAV\u30d9\u30af\u30bf\u30fc\u3001LNP\u306e\u81d3\u5668\u7279\u7570\u6027\u3001<br>\u7d30\u80de\u7279\u7570\u6027\u306f\u9ad8\u307e\u308a\u307e\u3059\u3067\u3057\u3087\u3046\u304b\uff1f&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">AAV\u306f\u8840\u6e05\u578b\u306b\u3088\u308a\u81d3\u5668\u7279\u7570\u6027\u304c\u7570\u306a\u308b\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u809d\u81d3\u306b\u306f<br>\u3069\u306e\u8840\u6e05\u578b\u3082\u6bd4\u8f03\u7684\u96c6\u7a4d\u3057\u6613\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<br>\u73fe\u5728\u306f\u7b4b\u8089\u306b\u884c\u304d\u3084\u3059\u3044\u3001\u8133\u3078\u306e\u4e2d\u67a2\u795e\u7d4c\u306b\u3044\u304d\u3084\u3059\u3044\u65b0\u3057\u3044\u8840\u6e05\u578b\u304c<br>\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>LNP\u3082\u809d\u81d3\u3078\u96c6\u7a4d\u3057\u3084\u3059\u3044\u306e\u3067\u3059\u304c\u3001LNP\u306e\u8868\u9762\u3092\u4fee\u98fe\u3057\u3066\u81d3\u5668\u7279\u7570\u6027\u3092<br>\u9ad8\u3081\u308b\u7814\u7a76\u3082\u9032\u3093\u3067\u3044\u307e\u3059\uff08\u5927\u68ee\uff09\u3002&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u907a\u4f1d\u5b50\u306e\u88dc\u5145\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u304c\u3001<br>\u6cbb\u7642\u306b\u306f\u7d99\u7d9a\u7684\u306b\u907a\u4f1d\u5b50\u3092\u88dc\u5145\u3059\u308b\u5fc5\u8981\u304c<br>\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">AAV\u30d9\u30af\u30bf\u30fc\u3067\u88dc\u5145\u3057\u305f\u907a\u4f1d\u5b50\u306f\u7d30\u80de\u306e\u6838\u306e\u4e2d\u3067\u74b0\u72b6\u306b\u306a\u3063\u3066\u5b89\u5b9a\u7684\u306b<br>\u5b58\u5728\u3057\u307e\u3059\u3002<br>\u7d30\u80de\u304c\u5206\u88c2\u3057\u306a\u3044\u72b6\u614b\uff08\u4e2d\u67a2\u795e\u7d4c\u3084\u5927\u4eba\u306e\u809d\u81d3\u306a\u3069\uff09\u3067\u306f\u5b89\u5b9a\u7684<br>\uff08\u304a\u305d\u3089\u304f\u6c38\u7d9a\u7684\u306b\uff09\u767a\u73fe\u304c\u6301\u7d9a\u3057\u307e\u3059\u3002<br>\u4e00\u65b9\u3001\u8840\u6db2\u306e\u7d30\u80de\uff08\u9020\u8840\u5e79\u7d30\u80de\uff09\u306a\u3069\u5206\u88c2\u3092\u7e70\u308a\u8fd4\u3059\u5834\u5408\u306b\u306fAAV\u304c<br>\u67d3\u8272\u4f53DNA\u306b\u306f\u7d44\u307f\u8fbc\u307e\u308c\u306b\u304f\u3044\u305f\u3081\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u306f\u5f90\u3005\u306b\u4f4e\u4e0b\u3057\u3066<br>\u3057\u307e\u3044\u307e\u3059\uff08\u5927\u68ee\uff09\u3002&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u9759\u8108\u6295\u4e0e\u306e\u5834\u5408\u3001\u809d\u81d3\u30fb\u80ba\u306b\u30c8\u30e9\u30c3\u30d7\u3055\u308c\u308b\u3068<br>\u805e\u3044\u305f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u5168\u8eab\u81d3\u5668\u306b\u907a\u4f1d\u5b50\u3092<br>\u30c7\u30ea\u30d0\u30ea\u30fc\u3067\u304d\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u8840\u7ba1\u5185\u306bAAV\u30d9\u30af\u30bf\u30fc\u3092\u6295\u4e0e\u3059\u308b\u3068\u4e3b\u306b\u809d\u81d3\u306b\u96c6\u7a4d\u3057\u3066\u3057\u307e\u3044\u307e\u3059<br>\u306e\u3067\u3001\u5fc3\u81d3\u3084\u7b4b\u8089\u3001\u81b5\u81d3\u3001\u306a\u3069\u809d\u81d3\u4ee5\u5916\u3078\u306e\u81d3\u5668\u306b\u907a\u4f1d\u5b50\u3092\u904b\u3076\u3053\u3068\u304c<br>\u3067\u304d\u308b\u3088\u3046\u306a\u30d9\u30af\u30bf\u30fc\u306e\u5de5\u592b\u304c\u7814\u7a76\u6bb5\u968e\u3067\u3059\uff08\u5927\u68ee\uff09\u3002&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u5b66\u8005\u306b\u306a\u308b\u306b\u306f\u3069\u306e\u3088\u3046\u306a\u77e5\u8b58\u304c<br>\u5fc5\u8981\u3067\u3057\u3087\u3046\u304b\uff1f<br>\u533b\u5b66\u90e8\u306b\u884c\u304b\u306a\u3044\u3068\u51fa\u6765\u306a\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u5206\u91ce\u306b\u9650\u3089\u305a\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u7814\u7a76\u306b\u306f\u533b\u5b66\u90e8\u4ee5\u5916\u306e\u51fa\u8eab\u8005\u306e<br>\u77e5\u8b58\u3082\u5fc5\u8981\u3067\u3059\u3002<br>\u7406\u5b66\u90e8\u3001\u5de5\u5b66\u90e8\u3001\u69d8\u3005\u306a\u30d0\u30c3\u30af\u30b0\u30e9\u30a6\u30f3\u30c9\u3092\u6301\u3064\u7814\u7a76\u8005\u304c\u77e5\u6075\u3092\u51fa\u3057\u5408\u3044\u3001<br>\u958b\u767a\u3057\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u3002<br>\u5b9f\u969b\u306b\u81ea\u6cbb\u533b\u5927\u3067\u3082\u533b\u5b66\u90e8\u51fa\u8eab\u4ee5\u5916\u306e\u7814\u7a76\u8005\u3082\u591a\u304f\u6d3b\u8e8d\u3057\u3066\u3044\u307e\u3059\uff08\u5927\u68ee\uff09\u3002&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u5e0c\u671b\u3057\u3066\u304b\u3089\u53d7\u3051\u3089\u308c\u308b\u3088\u3046\u306b<br>\u306a\u308b\u307e\u3067\u3001\u3069\u306e\u304f\u3089\u3044\u5f85\u3064\u3082\u306e\u3067\u3057\u3087\u3046\u304b\uff1f&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u73fe\u5728\u3001\u56fd\u5185\u3067\u5b9f\u65bd\u3055\u308c\u3066\u3044\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u307b\u3068\u3093\u3069\u306f\u6cbb\u9a13\u6bb5\u968e\u3067\u3059\u3002<br>\u305d\u306e\u5834\u5408\u3001\u7a2e\u3005\u306e\u9078\u629e\u6761\u4ef6\u306b\u5408\u81f4\u3059\u308b\u4eba\u306f\u3001\u6cbb\u9a13\u306e\u88ab\u9a13\u8005\u306b\u306a\u308b\u3053\u3068\u304c<br>\u3067\u304d\u307e\u3059\u3002\u6cbb\u9a13\u3067\u5b89\u5168\u6027\u3068\u52b9\u679c\u3092\u78ba\u8a8d\u3057\u3066\u4e00\u822c\u306b\u6cbb\u7642\u304c\u53d7\u3051\u3089\u308c\u308b\u3088\u3046\u306b<br>\u306a\u308b\u306b\u306f\u3001\u6cbb\u9a13\u958b\u59cb\u304b\u3089\u901a\u5e38\u306f\uff13\u301c\uff15\u5e74\u306f\u304b\u304b\u308a\u307e\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u3067\u81e8\u5e8a\u4e2d\u306e\u75be\u60a3\u4e00\u89a7\u3092<br>\u6559\u3048\u3066\u304f\u3060\u3055\u3044\u3002<br>\u307e\u305f\u306a\u305c\u305d\u308c\u3089\u306a\u306e\u304b\u3001\u3082\u3042\u308c\u3070<br>\u6559\u3048\u3066\u304f\u3060\u3055\u3044\u3002&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u3053\u308c\u307e\u3067\u306bAAV\u30d9\u30af\u30bf\u30fc\u3092\u4f7f\u7528\u3057\u305f\u6cbb\u9a13\u3092\u5b9f\u65bd\u3057\u305f\u75be\u60a3\u306f\u3001<br>\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3001\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\uff08ALS)\u3001\u82b3\u9999\u65cf\u30a2\u30df\u30ce\u9178\u8131\u70ad\u9178\u9175\u7d20<br>\uff08AADC)\u6b20\u640d\u75c7\u3067\u3059\u3002<br>\u6cbb\u9a13\u6e96\u5099\u4e2d\u306e\u75be\u60a3\u306f\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\uff11\u578b\u6b20\u640d\u75c7\u3001<br>Tay-Sachs\u75c5\u3001\u30aa\u30eb\u30cb\u30c1\u30f3\u30c8\u30e9\u30f3\u30b9\u30ab\u30eb\u30d0\u30df\u30e9\u30fc\u30bc\u6b20\u640d\u75c7\u3001<br>Niemann-Pick C\u578b\u3067\u3059\u3002<br>\u3053\u306e\u4ed6\u306b\u3082\u591a\u304f\u306e\u75be\u60a3\u306b\u3064\u3044\u3066\u7814\u7a76\u3057\u3066\u3044\u307e\u3059\u3002<br>\u3053\u308c\u3089\u306e\u75be\u60a3\u3092\u9078\u629e\u3057\u305f\u7406\u7531\u306f\u7a2e\u3005\u3067\u3059\u304c\u3001\u52d5\u7269\u5b9f\u9a13\u3067\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u308b\u3001<br>AMED\u306e\u7814\u7a76\u8cc7\u91d1\u304c\u5f97\u3089\u308c\u3066\u3044\u308b\u306a\u3069\u3067\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u30d3\u30aa\u30d7\u30c6\u30ea\u30f3\u4ee3\u8b1d\u7570\u5e38\u75c7\uff08PTPS\u6b20\u640d\uff09\u3092<br>\u60a3\u3063\u3066\u3044\u308b\u606f\u5b50\u304c\u3044\u307e\u3059\u3002&nbsp;<br>AADC\u6b20\u640d\u75c7\u3068\u5c11\u3057\u4f3c\u3066\u3044\u308b\u75c5\u306a\u306e\u304b\u306a\uff1f<br>\u3068\u8003\u3048\u307e\u3059\u304c\u3001PTPS\u6b20\u640d\u75c7\u3082\u8fd1\u3044\u5c06\u6765<br>\u907a\u4f1d\u5b50\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308b\u53ef\u80fd\u6027\u306f<br>\u3042\u308a\u307e\u3059\u304b\uff1f&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">PTPS\u6b20\u640d\u306b\u5bfe\u3057\u3066\u306f\u3001\u73fe\u6642\u70b9\u3067\u306f\u6cbb\u7642\u3067\u304d\u308b\u30ec\u30d9\u30eb\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u306f<br>\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u5bfe\u8c61\u306b\u306a\u308b\u75be\u60a3\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<br>\u3053\u308c\u304b\u3089\u306e\u7814\u7a76\u306e\u767a\u5c55\u3092\u671f\u5f85\u3057\u307e\u3059\u3002\u79c1\u3082\u3001\u30c1\u30a7\u30c3\u30af\u3057\u3066\u3044\u304d\u307e\u3059\u3002\uff08\u5c71\u5f62\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u59bb\u304cSCA3\u3067\u767a\u75c7\u306f55\u6b73\u3002<br>40\u6b73\u306e\u606f\u5b50\u304c\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u967d\u6027\u3002<br>\u907a\u4f1d\u3057\u305f\u5834\u5408\u3001\u5b50\u306e\u30ea\u30d4\u30fc\u30c8\u6570\u304c\u89aa\u3088\u308a\u5c11\u306a\u304f<br>\u306a\u308b\u3053\u3068\u306f\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<br>\u306a\u3044\u3068\u3057\u305f\u3089\u89aa\u306e\u767a\u75c7\u5e74\u9f62\u3092\u904e\u304e\u305f\u3089\u307b\u307c<br>\u907a\u4f1d\u3057\u3066\u3044\u306a\u3044\u3068\u8003\u3048\u3066\u3088\u3044\u306e\u3067\u3057\u3087\u3046\u304b\u3002&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">CAG\u30ea\u30d4\u30fc\u30c8\u75c5\u306e\u5834\u5408\u3001\u4e16\u4ee3\u3092\u7d4c\u308b\u3053\u3068\u306b\u30ea\u30d4\u30fc\u30c8\u306e\u5ef6\u9577\u304c\u751f\u3058\u3001<br>\u77ed\u304f\u306a\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u767a\u75c7\u5e74\u9f62\u306b\u3064\u3044\u3066\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001<br>\u78ba\u5b9a\u7684\u306a\u3053\u3068\u306f\u8a00\u3048\u307e\u305b\u3093\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">&nbsp;PD\u306e\u6cbb\u9a13\u3092\u6210\u529f\u3055\u305b\u6cbb\u7642\u304c\u53d7\u3051\u3089\u308c\u308b\u307e\u3067\u306b<br>\u69d8\u3005\u306a\u554f\u984c\u304c\u3042\u308b\u3068\u601d\u3044\u307e\u3059\u304c\u5148\u751f\u306e\u8996\u70b9\u3067<br>\uff13\u3064\u554f\u984c\u304c\u3042\u308b\u3068\u3059\u308b\u3068\u4f55\u3067\u3057\u3087\u3046\u304b\u3002&nbsp;<br>\u307e\u305f\u60a3\u8005\u3068\u3057\u3066\u3054\u5354\u529b\u304c\u3067\u304d\u308b\u3053\u3068\u304c\u3042\u308c\u3070<br>\u6559\u3048\u3066\u4e0b\u3055\u3044\u3002<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u7b2c\u4e00\u306b\u306f\u3001\u307e\u305a\u6cbb\u9a13\u3092\u5b9f\u65bd\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u3001\u305d\u308c\u306b\u306f\u9ad8\u984d\u306a\u8cbb\u7528\u3068<br>\u6642\u9593\u304c\u304b\u304b\u308a\u307e\u3059\u3002<br>\u60a3\u8005\u3055\u3093\u306b\u6295\u4e0e\u3059\u308b\u524d\u306b\u975e\u81e8\u5e8a\u8a66\u9a13\u3068\u3044\u3046\u52d5\u7269\u3092\u4f7f\u7528\u3057\u305f\u5b89\u5168\u6027\u8a66\u9a13\u3092<br>\u884c\u3044\u307e\u3059\u304c\u3001AAV\u30d9\u30af\u30bf\u30fc\u3092\u4f7f\u7528\u3057\u305f\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u5834\u5408\u3001\u76ee\u6a19\u3068\u3059\u308b\u75c5\u6c17\u306b<br>\u3088\u3063\u3066\u3001\u9055\u3046\u306e\u306f\u6cbb\u7642\u7528\u306e\u907a\u4f1d\u5b50\u3060\u3051\u3067\u3001\u305d\u308c\u3092\u642d\u8f09\u3059\u308bAAV\u30d9\u30af\u30bf\u30fc\u306f<br>\u540c\u3058\u3082\u306e\u3067\u3059\u3002<br>\u3053\u3046\u3057\u305f\u5834\u5408\u3001\u8a66\u9a13\u9805\u76ee\u306e\u591a\u304f\u306f\u7701\u7565\u3067\u304d\u308b\u306f\u305a\u306a\u306e\u3067\u3001\u305d\u306e\u3088\u3046\u306a<br>\u898f\u5236\u7de9\u548c\u304c\u671b\u307e\u308c\u307e\u3059\u3002<br>\u7b2c\u4e8c\u306b\u3001\u56fd\u5185\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u3078\u306e\u6295\u8cc7\u304c\u5727\u5012\u7684\u306b\u5c11\u306a\u3044\u3002<br>\u65e5\u672c\u306e\u88fd\u85ac\u4f01\u696d\u306f\u6d77\u5916\u306e\u4f01\u696d\u306b\u306f\u591a\u984d\u306e\u6295\u8cc7\u3092\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u56fd\u5185\u306b\u306f<br>\u9084\u5143\u3055\u308c\u306a\u3044\u306e\u306f\u6b8b\u5ff5\u306a\u3053\u3068\u3067\u3059\u3002<br>\u7b2c\u4e09\u306b\u306f\u3001\u60a3\u8005\u3055\u3093\u306e\u8981\u671b\u3092\u3082\u3063\u3068\u5c4a\u3051\u3066\u6b32\u3057\u3044\u3068\u8003\u3048\u307e\u3059\u3002<br>\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u60a3\u8005\u3055\u3093\u306f\u5fa1\u5bb6\u65cf\u306a\u3069\u95a2\u4fc2\u8005\u306f\uff11\uff10\uff10\u4e07\u4eba\u4ee5\u4e0a\u306b<br>\u306a\u308a\u307e\u3059\u3002<br>\u3053\u3046\u3044\u3063\u305f\u65b9\u306e\u58f0\u3092\u65e9\u671f\u627f\u8a8d\u3084\u8cc7\u91d1\u4e0d\u8db3\u306e\u89e3\u6d88\u306b\u7e4b\u3052\u3089\u308c\u308b\u3068\u3088\u3044\u3068<br>\u8003\u3048\u307e\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u6765\u5e74\u306e<br>\u6625\u9803\u304b\u3089\u6cbb\u9a13\u3092\u958b\u59cb\u3059\u308b\u3068\u805e\u3044\u3066\u3044\u307e\u3059\u304c\u3001<br>\u6cbb\u7642\u304c\u59cb\u307e\u3063\u305f\u5834\u5408\u3001\u5168\u56fd\u30671\u65e5\u4f55\u4eba\u7a0b\u5ea6\u306e<br>\u6cbb\u7642\u304c\u53ef\u80fd\u3068\u304a\u8003\u3048\u3067\u3057\u3087\u3046\u304b\u3002&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u3001\u6280\u8853\u7684\u306b\u306f\u8133\u795e\u7d4c\u5916\u79d1\u3067\u6df1\u90e8\u8133\u523a\u6fc0\u3092<br>\u5b9f\u65bd\u3057\u3066\u3044\u308b\u65bd\u8a2d\u3067\u306f\u3069\u3053\u3067\u3082\u53ef\u80fd\u3067\u3059\u3002<br>\u5e74\u9593\uff11,000\u4eba\u4ee5\u4e0a\u306f\u6cbb\u7642\u53ef\u80fd\u3068\u63a8\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u30e1\u30eb\u30af\u793e\u3068\u306e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u6839\u6cbb\u85ac\u306e<br>\u6cbb\u9a13\u306e\u65b0\u805e\u5831\u9053\u304c\u3042\u308a\u307e\u3057\u305f\u304c\u3001<br>\u305d\u306e\u5f8c\u306e\u9032\u6357\u304c\u3042\u308a\u307e\u3057\u305f\u3089<br>\u6559\u3048\u3066\u3044\u305f\u3060\u304d\u305f\u3044\u3067\u3059\u3002&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u5354\u696d\u3092\u6301\u7d9a\u3057\u3066\u3044\u307e\u3059\u3002\u6cbb\u9a13\u6e96\u5099\u4e2d\u3067\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">ADAR\u3069\u306e\u304f\u3089\u3044\u8cbb\u7528\u3067\u3057\u3087\u3046\u304b&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">ALS\u306b\u5bfe\u3059\u308bADAR2\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u8cbb\u7528\u306f\u672a\u5b9a\u3067\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">ADAR2\u306e\u6cbb\u9a13\u3067\u4eca\u52df\u96c6\u3057\u3066\u3044\u308b\u3082\u306e\u306f<br>\u3042\u308a\u307e\u3059\u304b\u3002&nbsp;<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u73fe\u5728\u306f\u52df\u96c6\u3057\u3066\u3044\u307e\u305b\u3093\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">ALS\u306f5\uff5e10\u5e74\u5f8c\u306b\u306f\u3042\u308b\u7a0b\u5ea6\u3001<br>\u6291\u5236\u3001\u6839\u672c\u7684\u306a\u6cbb\u7642\u304c\u3067\u304d\u308b\u3088\u3046\u306b<br>\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/td><td class=\"has-text-align-left\" data-align=\"left\">\u3042\u308b\u7a0b\u5ea6\u306e\u9032\u884c\u6291\u5236\u306f\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<br><\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group accordion_ttl\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading\">\u5e02\u6c11\u516c\u958b\u8b1b\u5ea7 \u30a2\u30f3\u30b1\u30fc\u30c8<\/h4>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group accordion_wrap\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u8cea\u554f<\/th><th>\u56de\u7b54<\/th><\/tr><\/thead><tbody><tr><td>PD\u306e\u6cbb\u7642\u5b9f\u7528\u5316\u306f\u3001\u3044\u3064\u9803\u306b\u306a\u308b\u304b&nbsp;<\/td><td>\uff13\u5e74\u4ee5\u5185\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td>\u764c\u306e\u8ee2\u79fb\u3001PD\u306e\u75c7\u72b6\u304c\u9032\u3093\u3060\u5834\u5408\u3001<br>80\u6b73\u3092\u8d85\u3048\u308b\u5e74\u9f62\u3067\u3042\u3063\u3066\u3082<br>\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u53ef\u80fd\u3067\u3057\u3087\u3046\u304b\u3002&nbsp;<\/td><td>\u5168\u8eab\u72b6\u614b\u6b21\u7b2c\u3067\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09&nbsp;<\/td><\/tr><tr><td>PD\u60a3\u8005\u3067\u3059\u3002<br>\u6cbb\u9a13\u3068\u6cbb\u7642\u958b\u59cb\u306e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u30fb<br>\u6cbb\u7642\u958b\u59cb\u6642\u306e\u6cbb\u7642\u8cbb\u30fb\u9069\u5408\u6027\u5224\u5b9a\u30fb<br>\u6cbb\u7642\u53ef\u80fd\u75c5\u9662\u540d\u304c\u77e5\u308a\u305f\u3044\u3002&nbsp;<\/td><td>\u6cbb\u9a13\u306f\u81ea\u6cbb\u533b\u5927\u75c5\u9662\u3068\u56fd\u7acb\u7cbe\u795e\u30fb\u795e\u7d4c\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u75c5\u9662\u3067\u3001<br>\u6765\u5e74\uff14\u6708\u4ee5\u964d\u5b9f\u65bd\u4e88\u5b9a\u3067\u3059\u3002<br>\u8a73\u7d30\u306f\u5f8c\u65e5\u3001\u516c\u8868\u3057\u307e\u3059\u3002&nbsp;<\/td><\/tr><tr><td>\u5a18\u304c3\u5e74\u524d\u306bsenda\/Bpan\u3068\u8a3a\u65ad\u3055\u308c\u3001<br>\u5f90\u3005\u306b\u4f53\u306e\u52d5\u304d\u304c\u60aa\u304f\u306a\u3063\u3066\u304a\u308a\u3001<br>\u3044\u305a\u308c\u5bdd\u305f\u304d\u308a\u306b\u306a\u308b\u3068\u601d\u308f\u308c\u308b\u3002<br>\u5a18\u304c\u52d5\u3051\u3066\u3044\u308b\u3046\u3061\u306b\u5e0c\u671b\u304c\u6301\u3066\u308b<br>\u6cbb\u7642\u6cd5\u304c\u78ba\u7acb\u3067\u304d\u305d\u3046\u304b\uff1f&nbsp;<\/td><td>\u78ba\u7acb\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u304c\u3001\u500b\u4eba\u306e\u52aa\u529b\u3060\u3051\u3067\u306f\u3069\u3046\u306b\u3082\u306a\u3089\u306a\u3044<br>\u969c\u58c1\u304c\u5927\u304d\u3044\u3053\u3068\u3082\u4e8b\u5b9f\u3067\u3059\u3002<br>\u60a3\u8005\u3055\u3093\u3001\u56fd\u3001\u4f01\u696d\u3001\u7814\u7a76\u8005\u304c\u4e00\u4f53\u3068\u306a\u3063\u3066\u9032\u3081\u3066\u3044\u304f\u3053\u3068\u304c\u3067\u304d\u308c\u3070\u3001<br>\u9032\u5c55\u3082\u65e9\u304f\u306a\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u671f\u5f85\u3057\u3066\u307e\u3059\u3002\uff08\u6751\u677e\u4e00\u6d0b\uff09&nbsp;<\/td><\/tr><tr><td>SENDA BPAN\u767a\u75c7\u5f8c\u3001\u5c11\u3057\u3067\u3082\u9577\u304f<br>\u4eca\u306e\u72b6\u614b\u3092\u4fdd\u3061\u305f\u3044\u3002<br>\u6cbb\u9a13\u304c\u59cb\u307e\u3063\u3066\u3044\u308b\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e<br>\u907a\u4f1d\u5b50\u6cbb\u7642\u6cd5\u306f\u6709\u52b9\u3067\u3057\u3088\u3046\u304b\uff1f&nbsp;<\/td><td>\u30c9\u30d1\u30df\u30f3\u4f5c\u52d5\u85ac\u304c\u3042\u308b\u7a0b\u5ea6\u3001\u52b9\u304f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u4eca\u306e\u3068\u3053\u308d\u3001<br>\u671f\u9593\u3082\u9650\u3089\u308c\u52b9\u679c\u3082\u6c7a\u3057\u3066\u5341\u5206\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<br>\u307e\u305f\u3001\u30c9\u30d1\u30df\u30f3\u3060\u3051\u88dc\u5145\u3057\u3066\u89e3\u6c7a\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3082\u306a\u3044\u306e\u3067\u3001<br>\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u5b9f\u65bd\u3057\u305f\u3068\u3057\u3066\u3082\u3001\u671f\u5f85\u901a\u308a\u306e\u52b9\u679c\u306f<br>\u96e3\u3057\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\uff08\u6751\u677e\u4e00\u6d0b\uff09<\/td><\/tr><tr><td>senda,bpan\u306e\u6cbb\u7642\u958b\u767a\u306e\u9032\u884c\u72b6\u6cc1&nbsp;<\/td><td>\u907a\u4f1d\u5b50\u6cbb\u7642\u3092\u958b\u767a\u4e2d\u3067\u3059\u3002<br>\u52d5\u7269\u5b9f\u9a13\u3067\u6210\u679c\u304c\u5f97\u3089\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002\uff08\u6751\u677e\u614e\u4e00\uff09<br>\u907a\u4f1d\u5b50\u6cbb\u7642\u3068\u306e\u76f8\u4e57\u52b9\u679c\u3092\u671f\u5f85\u3057\u3066\u3001\u5275\u85ac\u7814\u7a76\u3082\u958b\u59cb\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001<br>\u3053\u3061\u3089\u306f\u307e\u3060\u307e\u3060\u59cb\u307e\u3063\u305f\u3070\u304b\u308a\u3067\u3059\u3002\uff08\u6751\u677e\u4e00\u6d0b\uff09&nbsp;<\/td><\/tr><tr><td>SENDA BPAN\u767a\u75c7\u5f8c\u306e\u6cbb\u7642\u6cd5\u306b\u3064\u3044\u3066&nbsp;<\/td><td>\u75c7\u72b6\u304c\u9032\u884c\u3057\u305f\u969b\u306e\u6cbb\u7642\u6cd5\u306f\u5341\u5206\u306b\u6709\u52b9\u306a\u3082\u306e\u304c\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002<br>\u30c9\u30d1\u30df\u30f3\u4f5c\u52d5\u85ac\u306f\u3042\u308b\u7a0b\u5ea6\u3001\u52b9\u304f\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u4eca\u306e\u3068\u3053\u308d\u3001<br>\u671f\u9593\u3082\u9650\u3089\u308c\u52b9\u679c\u3082\u6c7a\u3057\u3066\u5341\u5206\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\uff08\u6751\u677e\u4e00\u6d0b\uff09&nbsp;<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div><\/div>\n<\/div><\/div>\n\n\n<p><!-- \/wp:post-content --><\/p>\n<p><!-- wp:paragraph --><\/p>\n<p><!-- \/wp:paragraph --><\/p>\n<p><!-- wp:paragraph --><\/p>\n<p><!-- \/wp:paragraph --><\/p>","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u7d39\u4ecb &#x25fc;\ufe0e\u8102\u8cea\u30ca\u30ce\u7c92\u5b50\u3092\u7528\u3044\u305f\u5869\u57fa\u7de8\u96c6\u306b\u3088\u308a\u8840\u53cb\u75c5B\u306e\u539f\u56e0\u907a\u4f1d\u5b50\u5909\u7570\u3092\u30de\u30a6\u30b9\u3067\u4fee\u5fa9\u2015 \u907a\u4f1d\u5b50\u88dc\u5145\u7642\u6cd5\u306b\u4ee3\u308f\u308b\u65b0\u305f\u306a\u6839\u6cbb\u7684\u30b2\u30ce\u30e0\u7de8\u96c6\u6cbb\u7642\u306e\u53ef\u80fd\u6027 \u2015 \u81ea\u6cbb\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u75c5\u614b\u751f\u5316\u5b66\u90e8\u9580\u3068\u5317\u6d77\u9053\u5927\u5b66\u306e\u7814\u7a76\u30b0\u30eb [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-19","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/pages\/19","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/comments?post=19"}],"version-history":[{"count":10,"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/pages\/19\/revisions"}],"predecessor-version":[{"id":1505,"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/pages\/19\/revisions\/1505"}],"wp:attachment":[{"href":"https:\/\/www.jichi.ac.jp\/jmu-cgtr\/wp-json\/wp\/v2\/media?parent=19"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}