EZR version 1.61 now available! (November 11, 2022)

Propensity score variable and IPTW option added ! Network metaanalysis function added !
Enabled time-dependent covariates in Fine-Gray regression !

Enabled current survival function and swimmer plot in addition to waterfall plot!
Update history is shown here.

For Windows XP - 11, Mac OS X Snow Leopard - Ventura, Ubuntu 11.10 - 20.04

Please cite the following paper as a reference for scientific papers in which EZR is used as a statistical software. This paper has been cited by more than 8000 scientific articles at November 2022..
Bone Marrow Transplantation 2013: 48, 452–458

Included in the Softpedia software database with "100% CLEAN" software award.

Free statistical software: EZR on R commander   R is a free software environment for statistical computing and graphics. R supports many functions for statistical analyses, but it does not incorporate statistical graphical user interface (GUI). The R commander provides a easy-to-use basic-statistics GUI to R based on Tcl/Tk language. However, the statistical function of the R commander is limited, especially in the field of biostatistics. Therfore, we added statistical functions, including survival analyses, ROC analyses, metaanalyses, sample size calculation, and so on, to the R commander. We named it "EZR" (Easy R) and we are distributing it on this page. EZR can import Excel files, CSV files, Stata files, and so on. EZR is now available on CRAN (The Comprehensive R Archive Network) as "RcmdrPlugin.EZR" package. Contact address: Yoshinobu Kanda, M.D., saitama-hem@jichi.ac.jp.

Statistical functions of EZR

A complete manual of EZR is available only in Japanese (Chugai Igakusha, ISBN978-4-498-10901-8), but a report that introduced the investigation of EZR was published in Bone Marrow Transplantation (Nature Publishing Group) as an Open article. It can be freely downloaded from the journal website (Kanda Y. Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplantation 2013:48,452-458 advance online publication 3 December 2012; doi: 10.1038/bmt.2012.244). This paper has been cited in more than 8000 articles at November 2022.

Following instructions are written in Japanese, but you can download them, and translate into English using Google translator and so on.

Propensity score analysis instructions (including inversed probability weighting)
Current leukemia-free survival
Waterfall plot and swimmer plot

* From version 1.52, EZR allows multiple time-dependent covariates in Cox proportional hazard modeling, and the dialogue was changed. Now, it is unnecessary to select the 'TD covariate’ and just select the 'Time when TD covariate changes from 0 to 1'. The 'Time when TD covariate changes from 0 to 1' should be time to last follow-up for patients who did not develop the event for time-dependent covariate.

Please cite this report as a reference for scientific papers in which EZR is used as a statistical software.

 In addition, Professor Minato Nakazawa (Kobe Univ. Grad. School Heallth Sci.) is providing an excellent manual for the use of R and EZR in medical statics on his homepage. It can be downloaded from the link below. (He told me that there may be some typos and mistakes, which will be fixed in the future.)

Medical Statistics for Gunma Univ. Graduate School of Medicine

Sample data set that includes 93 fictional patients who received allogeneic stem cell transplantation for acute leukemia.

Click to view large images.

EZR menu

Summary of analysis

Survival analysis

Kaplan-Meier plot

ROC analysis