自治医科大学細菌学部門

Overview of Our Research

Our research interests encompass the pathogenicity and antimicrobial resistance of bacteria involved in infections, host defense mechanisms against these pathogens, and drug discovery for infectious diseases. In recent years, we have focused on drug discovery using bacteriophages as a novel therapeutic modality. Our work includes the development of phage-based therapeutics for bacterial infections and cancer therapy, as well as the design of phage-based vaccines.

1. Development of a novel bacterium-tracking antimicrobial therapy against antimicrobial-resistant bacteria

2a. Heterogeneity of bacterial populations and its impact on the chronic persistent infection in human

2b. Antibiotic resistance in staphyloccocal species, especitally in Staphylococcus aureus

3. Drug resistance in GN pathogenes

We also research on antibiotic resistance of opportunistic pathogens including K. pneumoniae, P. aeruginosa and A. baumannii, etc.

4. Severe invasive infection by group A streptococci

5. Infection control science

In collaboration with clinical laboratory, our group supports infection control management in university teaching hospital by carrying out basic study and laboratory surveillance.