自治医科大学 炎症・免疫研究部
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自治医大HPに戻る

2017
1. Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, Takahashi M. Saturated fatty acids undergo intracellular crystallization and activate the NLRP3 inflammasome in macrophages. Arterioscler Thromb Vasc Biol 38:744-756, 2018

2. Nakamura J, Watanabe S, Kimura H, Kobayashi M, Karasawa T, Kamata R, Usui-Kawanishi F, Sadatomo A, Mizukami H, Nagi-Miura N, Ohno N, Kasahara T, Minota S, Takahashi M. Adeno-associated vector-mediated interleukin-10 induction prevents vascular inflammation in a murine model of Kawasaki disease. Sci Rep (in press)

3. Karasawa T, Takahashi M. The crystal-induced activation of NLRP3 inflammasomes in atherosclerosis. Inflammation and Regeneration 37: 18, 2017

4. Kawashima A, Karasawa T, Tago K, Kimura H, Kamata R, Usui-Kawanishi F, Watanabe S, Ohta S, Funakoshi-Tago M, Yanagisawa K, Kasahara T, Suzuki K, Takahashi M. ARIH2 ubiquitinates NLRP3 and negatively regulates NLRP3 inflammasome activation in macrophages. J Immunol 199: 3614-3622, 2017

5. Sadatomo A, Inoue Y, Ito H, Karasawa T, Kimura H, Watanabe S, Mizushina Y, Nakamuara J, Kamata R, Kasahara T, Horie H, Sata N, Takahashi M. Interaction of neutrophils with macrophages promotes interleukin-1β maturation and contributes to hepatic ischemia-reperfusion injury. J Immunol 199: 3306-3315, 2017

6. Kobayashi M, Kawanishi-Usui F, Karasawa T, Kimura H, Watanabe S, Mise N, Kayama F, Kasahara T, Hasebe N, Takahashi M. The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. PLoS One 12: 176676, 2017

7. Karasawa T, Takahashi M. Role of NLRP3 inflammasomes in atherosclerosis.
J Atheroscler Thromb
24: 443-451, 2017

8. Sogawa Y, Nagasu H, Iwase S, Ihoriya C, Itano S, Uchida A, Kidokoro K, Taniguchi S, Takahashi M, Satoh M, Sasaki T, Suzuki T, Yamamoto M, Horng T, Kashihara N. Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice. Sci Rep 7: 8801, 2017

9. Terai S, Hashimoto Y, Orita K, Yamasaki S, Takigami J, Shinkuma T, Teraoka T, Nishida Y, Takahashi M, Nakamura H. The origin and distribution of CD68, CD163 and alpha SMA positive cells in the early phase after meniscal resection in a parabiotic rat model. Connect Tissue Res 6: 1-11, 2017