自治医科大学 炎症・免疫研究部
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自治医大HPに戻る

2018
1. Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, Takahashi M. Saturated fatty acids undergo intracellular crystallization and activate the NLRP3 inflammasome in macrophages. Arterioscler Thromb Vasc Biol 38: 744-756, 2018

2. Nakamura J, Watanabe S, Kimura H, Kobayashi M, Karasawa T, Kamata R, Usui-Kawanishi F, Sadatomo A, Mizukami H, Nagi-Miura N, Ohno N, Kasahara T, Minota S, Takahashi M. Adeno-associated vector-mediated interleukin-10 induction prevents vascular inflammation in a murine model of Kawasaki disease. Sci Rep 8: 7601, 2018

3. Takahashi M. Role of NLRP3 inflammasome in cardiac inflammation and remodeling after myocardial infarction. Biol Pharm Bull (in press)

4. Shirasuna K, Karasawa T, Takahashi M. Exogenous nanoparticles and endogenous crystalline molecules as danger signals for the NLRP3 inflammasomes. J Cell Physiol 234: 5436-5450, 2019

5. Zuurbier CJ, Abbate A, Cabrera-Fuentes HA, Cohen MV, Collino M, De Kleijn DPV, Downey JM, Pagliaro P, Preissner KT, Takahashi M, Davidson SM, on behalf of the EU-CARDIOPROTECTION COST Action (CA16225). Innate immunity as a target for acute cardioprotection. Cardiovasc Res (in press)

6. Yamada N, Katano T, Hirata Y, Okada N, Sanada Y, Ihara Y, Urahashi T, Ushijima K, Karasawa T, Takahashi M, Mizuta K. Serum Mac2 binding protein glycosylation isomer predicts the activation of hepatic stellate cells after liver transplantation. J Gastroenterol Hepatol 34: 418-424, 2019

7. Wakabayashi T, Takahashi M, Yamamoto D, Kasahara T, Takei A, Takei S, Yamazaki H, Nagashima S, Ebihara K, Takahashi M, Ishibashi S. Inflammasome activation aggravates cutaneous xanthomatosis and atherosclerosis in acyl-CoA cholesterol acyltransferase 1 deficiency in bone marrow. Arterioscler Thromb Vasc Biol 38: 2576-2589, 2018

8. Sakai K, Nagashima S, Wakabayashi T, Bayasgalan T, Hayakawa H, Hayakawa M, Kasahara T, Ohashi K, Yamazaki H, Takei A, Takei S, Yamamoto D, Takahashi M, Yagyu H, Osuga J, Takahashi M, Tominaga S, Ishibashi S. Myeloid HMG-CoA reductase determines atherosclerosis by modulating migration of macrophages. Arterioscler Thromb Vasc Biol 38: 2590-2600, 2018

9. Sogawa Y, Hagasu H, Uchida A, KidokoroK, Taniguchi S, Takahashi M, Kadoya H, Satoh M, Sasaki T, Kashihara N. The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice. PLoS One 13: e0203823, 2018

10. Murakami T, Ruengsinpinya L, Nakamura E, Takahata Y, Hata K, Okae H, Taniguchi S, Takahashi M, Nishimura R. G protein subunit beta 1 negatively regulates NLRP3 inflammasome activation. J Immunol (in press)